JPH06507886A - ロイコトリエン・アンタゴニスト - Google Patents

ロイコトリエン・アンタゴニスト

Info

Publication number
JPH06507886A
JPH06507886A JP4508344A JP50834492A JPH06507886A JP H06507886 A JPH06507886 A JP H06507886A JP 4508344 A JP4508344 A JP 4508344A JP 50834492 A JP50834492 A JP 50834492A JP H06507886 A JPH06507886 A JP H06507886A
Authority
JP
Japan
Prior art keywords
compound according
quinolinyl
formula
pharmaceutically acceptable
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4508344A
Other languages
English (en)
Japanese (ja)
Inventor
デイニーズ，ロバート・エイ
キングスベリー，ウイリアム・ディー
ペンドラク，イスライル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH06507886A publication Critical patent/JPH06507886A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP4508344A 1991-03-13 1992-03-13 ロイコトリエン・アンタゴニスト Pending JPH06507886A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66866391A 1991-03-13 1991-03-13
US668,663 1991-03-13
PCT/US1992/002114 WO1992016104A1 (en) 1991-03-13 1992-03-13 Leukotriene antagonists

Publications (1)

Publication Number Publication Date
JPH06507886A true JPH06507886A (ja) 1994-09-08

Family

ID=24683267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4508344A Pending JPH06507886A (ja) 1991-03-13 1992-03-13 ロイコトリエン・アンタゴニスト

Country Status (4)

Country Link
EP (1) EP0575494A1 (enrdf_load_stackoverflow)
JP (1) JPH06507886A (enrdf_load_stackoverflow)
AU (1) AU1583392A (enrdf_load_stackoverflow)
WO (1) WO1992016104A1 (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9400809D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of quinoline-3-carboxamide compounds
SE9400810D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of Quinoline-3-carboxamide compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8301377D0 (en) * 1983-01-19 1983-02-23 Wyeth John & Brother Ltd Quinoline derivatives
GB8814458D0 (en) * 1988-06-17 1988-07-20 Wyeth John & Brother Ltd Heterocyclic compounds
NZ233752A (en) * 1989-05-24 1993-05-26 Merck Frosst Canada Inc Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof
US4996214A (en) * 1990-06-28 1991-02-26 Smithkline Beecham Corporation Quinolinyl substituted phenyl/thioalkanoic acid substituted propionic acids and leucotriene antagonist use thereof

Also Published As

Publication number Publication date
WO1992016104A1 (en) 1992-10-01
AU1583392A (en) 1992-10-21
EP0575494A1 (en) 1993-12-29
EP0575494A4 (enrdf_load_stackoverflow) 1994-04-20

Similar Documents

Publication Publication Date Title
US5130318A (en) Angiotensin ii antagonizers which are condensed pyridine derivatives
TWI406856B (zh) 人類免疫缺乏病毒複製之抑制劑
EP0425650B1 (en) Anti-inflammatory 4-aminophenol derivatives
JP3900720B2 (ja) キノリノン誘導体の製造方法
EP1453512A1 (en) Acetylene derivatives having mglur 5 antagonistic activity
EP0271287A2 (en) Quinoline dioic acids and amides
US4851409A (en) 2-substituted quinoline dioic acids and pharmaceutical compositions
DE69204252T2 (de) Chinoline Derivate, nützlich als Angiotensin-II-Antagonisten.
JPH02290869A (ja) 喘息、関節炎及び関連疾患の治療における置換クロマン
KR870001915B1 (ko) 피리딜 화합물의 제조방법
TW200418840A (en) Process for preparing ARIPIPRAZOLE
EP0219308B1 (en) 2-substituted quinolines
EP0160578B1 (en) 1,8-naphthyridine derivatives
JPS62187459A (ja) ５−アミノおよび５−ヒドロキシ−６，８−ジフルオロキノロン化合物
PT88781B (pt) Processo para a preparacao de tetralinas, cromanos e compostos relacionados substituiidos, uteis no tratamento da asma
JPH06507886A (ja) ロイコトリエン・アンタゴニスト
US5508309A (en) LTB4 synthesis inhibitors
JPH0678340B2 (ja) 喘息、関節炎および関連疾患の治療におけるアザベンジミダゾール
EP0532550A1 (en) Benzoic acid derivatives for treating leukotriene-related diseases
JPH07507795A (ja) カンプトテシンおよびカンプトテシン類似体の不斉合成の方法および中間体
CN1057834A (zh) 用于治疗与白三烯有关的疾病的酰胺连接的吡啶-苯甲酸衍生物
US4707473A (en) 4-monosubstituted and 4,6-disubstituted phenoxazines
WO1993022285A1 (en) Leukotriene antagonists
US5198439A (en) Angiotension II antagonizing pyridine derivatives
AU686820B2 (en) Quinoline derivatives as leukotriene antagonists