JPH06504935A - 錠剤における陰刻を目だたせる方法 - Google Patents
錠剤における陰刻を目だたせる方法Info
- Publication number
- JPH06504935A JPH06504935A JP4504904A JP50490492A JPH06504935A JP H06504935 A JPH06504935 A JP H06504935A JP 4504904 A JP4504904 A JP 4504904A JP 50490492 A JP50490492 A JP 50490492A JP H06504935 A JPH06504935 A JP H06504935A
- Authority
- JP
- Japan
- Prior art keywords
- tablets
- tablet
- solvent
- waxy
- coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Cosmetics (AREA)
- Color Printing (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Paper (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Description
Claims (10)
- 1.白色のまたは着色したコーティング錠剤上に異なる色を有する充填物質、ワ ックス状物質および溶媒を含んでなる懸濁液を噴霧し、そして溶媒並びに過剰の 充填物質およびワックス状物質を除去することを特徴とする、白色のまたは着色 したコーティング錠剤における陰刻を目だたせる方法。
- 2.充填物質がトウモロコシ澱粉または徴結晶性セルロースである請求の範囲第 1項に記載の方法。
- 3.充填物質があらかじめ可食性レーキ顔料で染色されている請求の範囲第2項 に記載の方法。
- 4.ワックス状物質がポリエチレングリコールである請求の範囲第1、2または 3項に記載の方法。
- 5.ワックス状物質対充填物質の重量対重量比が1:3〜1:12の範囲内にあ る請求の範囲第4項に記載の方法。
- 6.溶媒が充填物質も存在する場合の染料も溶解しないものである請求の範囲第 1〜5項のいずれかに記載の方法。
- 7.最終的懸濁液中の溶媒の量が70%〜85%の範囲内にある請求の範囲第6 項に記載の方法。
- 8.溶媒並びに過剰の充填物質およびワックス状物質を空気を用いる吹き出しお よび錠剤の回転維持により除去する請求の範囲第7項に記載の方法。
- 9.充填された錠剤に別のコーティングフィルムを提供する請求の範囲第1〜8 項のいずれかに記載の方法。
- 10.請求の範囲第1〜9項のいずれかに記載の方法により得られる錠剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91200417 | 1991-02-27 | ||
EP91,200,417,3 | 1991-02-27 | ||
PCT/EP1992/000358 WO1992015288A1 (en) | 1991-02-27 | 1992-02-14 | A method of highlighting intagliations in tablets |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH06504935A true JPH06504935A (ja) | 1994-06-09 |
JP3237758B2 JP3237758B2 (ja) | 2001-12-10 |
Family
ID=8207528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50490492A Expired - Lifetime JP3237758B2 (ja) | 1991-02-27 | 1992-02-14 | 錠剤における陰刻を目だたせる方法 |
Country Status (16)
Country | Link |
---|---|
US (1) | US5405642A (ja) |
EP (2) | EP0501553A1 (ja) |
JP (1) | JP3237758B2 (ja) |
AT (1) | ATE143259T1 (ja) |
AU (1) | AU1260392A (ja) |
CA (1) | CA2104096C (ja) |
DE (1) | DE69214130T2 (ja) |
DK (1) | DK0573462T3 (ja) |
ES (1) | ES2094902T3 (ja) |
GR (1) | GR3021929T3 (ja) |
IE (1) | IE75729B1 (ja) |
MX (1) | MX9200831A (ja) |
NZ (1) | NZ241613A (ja) |
TW (1) | TW201697B (ja) |
WO (1) | WO1992015288A1 (ja) |
ZA (1) | ZA921428B (ja) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6113945A (en) * | 1996-02-26 | 2000-09-05 | L. Perrigo Company | Multi-colored medicament |
US5827535A (en) * | 1996-06-21 | 1998-10-27 | Banner Pharmacaps, Inc. | Graphically impressed softgel and method for making same |
ATE195871T1 (de) * | 1997-09-23 | 2000-09-15 | Akzo Nobel Nv | Steroid enthaltende dosierungsformen mit einer steroiddichten umhüllung |
US6685961B1 (en) | 2000-10-24 | 2004-02-03 | Banner Pharmacaps, Inc. | Colored gelatin-based formulations and method |
GB0110846D0 (en) * | 2001-05-02 | 2001-06-27 | Phoqus Ltd | Tablets with coloured patterns |
US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
US6837696B2 (en) * | 2001-09-28 | 2005-01-04 | Mcneil-Ppc, Inc. | Apparatus for manufacturing dosage forms |
US7122143B2 (en) * | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
US7323192B2 (en) * | 2001-09-28 | 2008-01-29 | Mcneil-Ppc, Inc. | Immediate release tablet |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
ATE376826T1 (de) * | 2001-09-28 | 2007-11-15 | Mcneil Ppc Inc | Darreichungsformen zur modifizierten freisetzung |
UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
JP4520305B2 (ja) * | 2002-06-26 | 2010-08-04 | マース インコーポレーテッド | 食用被印刷物にインクジェット印刷するための食用インク |
US7029112B2 (en) * | 2002-08-05 | 2006-04-18 | Mars, Incorporated | Ink-jet printing on surface modified edibles and products made |
US7807197B2 (en) * | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
US7906167B2 (en) | 2003-03-07 | 2011-03-15 | Mars Incorporated | Water based inks for printing on confectionery |
US20050074514A1 (en) * | 2003-10-02 | 2005-04-07 | Anderson Oliver B. | Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms |
US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
NZ551340A (en) * | 2004-04-22 | 2010-10-29 | Boehringer Ingelheim Int | Pharmaceutical composition comprising flibanserin and a melanocortin agonist for the treatment of premenstrual disorder or sexual aversion disorder |
US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
JP2008511569A (ja) * | 2004-09-03 | 2008-04-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 注意欠如活動過多障害の治療方法 |
US20070281022A1 (en) * | 2004-10-27 | 2007-12-06 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US20060088587A1 (en) * | 2004-10-27 | 2006-04-27 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US20060087051A1 (en) * | 2004-10-27 | 2006-04-27 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US20060088586A1 (en) * | 2004-10-27 | 2006-04-27 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US20070190133A1 (en) * | 2004-10-27 | 2007-08-16 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US8383159B2 (en) * | 2004-10-27 | 2013-02-26 | Mcneil-Ppc, Inc. | Dosage forms having a microreliefed surface and methods and apparatus for their production |
US20060088593A1 (en) * | 2004-10-27 | 2006-04-27 | Bunick Frank J | Dosage forms having a microreliefed surface and methods and apparatus for their production |
JP2008538741A (ja) * | 2005-03-04 | 2008-11-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 鬱病の治療用及び/又は予防用の医薬組成物 |
WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
JP2008531714A (ja) * | 2005-03-04 | 2008-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 不安障害の治療用及び/又は予防用の医薬組成物 |
US8673352B2 (en) * | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
JP2008540356A (ja) * | 2005-05-06 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 薬物乱用の治療方法 |
WO2006125042A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug-induced sexual dysfunction |
CA2608713A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of sexual dysfunctions due to medical conditions |
PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
WO2007035926A2 (en) * | 2005-09-22 | 2007-03-29 | Bpsi Holdings, Inc. | Method for printing on tablets and etched printing plate used therein |
US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
CA2626134C (en) * | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
ES2551093T3 (es) * | 2006-05-09 | 2015-11-16 | Sprout Pharmaceuticals, Inc. | Uso de flibanserina para el tratamiento de trastornos del deseo sexual después de la menopausia |
JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
WO2008006838A1 (en) * | 2006-07-14 | 2008-01-17 | Boehringer Ingelheim International Gmbh | Use of flibanserin for the treatment of sexual disorders in females |
JP5793828B2 (ja) * | 2006-08-14 | 2015-10-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | フリバンセリンの製剤及びその製造方法 |
CL2007002214A1 (es) * | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
EP2056797A2 (en) * | 2006-08-25 | 2009-05-13 | Boehringer Ingelheim International GmbH | Controlled release system and method for manufacturing the same |
CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3125490A (en) * | 1964-03-17 | Tablet with contrasting indicia and method | ||
US3436453A (en) * | 1963-06-14 | 1969-04-01 | American Cyanamid Co | Surface dyed edible gelatin capsule with pigment marking |
FR1426194A (fr) * | 1964-10-20 | 1966-01-28 | Ile De France | Nouvelle technique d'enrobage des comprimés |
US3539380A (en) * | 1968-01-08 | 1970-11-10 | Upjohn Co | Methylcellulose and polyalkylene glycol coating of solid medicinal dosage forms |
IE53157B1 (en) * | 1981-03-09 | 1988-08-03 | Ici Plc | Coated coloured intagliated articles |
JPS58152813A (ja) * | 1982-03-08 | 1983-09-10 | Sumitomo Chem Co Ltd | 鮮明な刻印を有する錠剤およびその製法 |
JPS58192819A (ja) * | 1982-05-04 | 1983-11-10 | Sumitomo Chem Co Ltd | 鮮明な刻印を有する錠剤の製法 |
KR840000624A (ko) * | 1982-06-02 | 1984-02-25 | 원본미기재 | 부식억제 페인트 조성물 |
EP0096982B1 (en) * | 1982-06-10 | 1987-09-16 | Imperial Chemical Industries Plc | Manufacture of highlighted intagliated articles |
FR2548675B1 (fr) * | 1983-07-06 | 1987-01-09 | Seppic Sa | Compositions filmogenes pour enrobage des formes solides de produits pharmaceutiques ou alimentaires et produits obtenus revetus desdites compositions |
US4576646A (en) * | 1983-07-06 | 1986-03-18 | Seppic | Film-forming compositions for enveloping solid forms, particularly pharmaceutical or food products or seeds, and products obtained, coated with said compositions |
US5006362A (en) * | 1988-05-09 | 1991-04-09 | Berwind Pharmaceutical Services, Inc. | Branding pharmaceutical dosage forms, food and confectionery products with aqueous ingestible inks |
US5098715A (en) * | 1990-12-20 | 1992-03-24 | Burroughs Wellcome Co. | Flavored film-coated tablet |
-
1992
- 1992-02-13 NZ NZ241613A patent/NZ241613A/xx not_active IP Right Cessation
- 1992-02-14 DE DE69214130T patent/DE69214130T2/de not_active Expired - Lifetime
- 1992-02-14 US US08/094,137 patent/US5405642A/en not_active Expired - Lifetime
- 1992-02-14 JP JP50490492A patent/JP3237758B2/ja not_active Expired - Lifetime
- 1992-02-14 DK DK92904760.3T patent/DK0573462T3/da active
- 1992-02-14 ES ES92904760T patent/ES2094902T3/es not_active Expired - Lifetime
- 1992-02-14 WO PCT/EP1992/000358 patent/WO1992015288A1/en active IP Right Grant
- 1992-02-14 AU AU12603/92A patent/AU1260392A/en not_active Abandoned
- 1992-02-14 CA CA002104096A patent/CA2104096C/en not_active Expired - Lifetime
- 1992-02-14 EP EP92200418A patent/EP0501553A1/en active Pending
- 1992-02-14 AT AT92904760T patent/ATE143259T1/de active
- 1992-02-14 EP EP92904760A patent/EP0573462B1/en not_active Expired - Lifetime
- 1992-02-25 TW TW081101368A patent/TW201697B/zh active
- 1992-02-26 MX MX9200831A patent/MX9200831A/es unknown
- 1992-02-26 ZA ZA921428A patent/ZA921428B/xx unknown
- 1992-02-26 IE IE920611A patent/IE75729B1/en not_active IP Right Cessation
-
1996
- 1996-12-06 GR GR960403339T patent/GR3021929T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3021929T3 (en) | 1997-03-31 |
US5405642A (en) | 1995-04-11 |
DE69214130D1 (de) | 1996-10-31 |
AU1260392A (en) | 1992-10-06 |
ATE143259T1 (de) | 1996-10-15 |
EP0501553A1 (en) | 1992-09-02 |
IE920611A1 (en) | 1992-09-09 |
MX9200831A (es) | 1992-08-01 |
JP3237758B2 (ja) | 2001-12-10 |
ZA921428B (en) | 1993-08-26 |
CA2104096C (en) | 2003-06-10 |
DE69214130T2 (de) | 1997-02-06 |
DK0573462T3 (da) | 1996-11-11 |
IE75729B1 (en) | 1997-09-24 |
NZ241613A (en) | 1993-06-25 |
CA2104096A1 (en) | 1992-08-28 |
WO1992015288A1 (en) | 1992-09-17 |
EP0573462A1 (en) | 1993-12-15 |
ES2094902T3 (es) | 1997-02-01 |
EP0573462B1 (en) | 1996-09-25 |
TW201697B (ja) | 1993-03-11 |
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