JPH064667B2 - ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法 - Google Patents

ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法

Info

Publication number
JPH064667B2
JPH064667B2 JP63257376A JP25737688A JPH064667B2 JP H064667 B2 JPH064667 B2 JP H064667B2 JP 63257376 A JP63257376 A JP 63257376A JP 25737688 A JP25737688 A JP 25737688A JP H064667 B2 JPH064667 B2 JP H064667B2
Authority
JP
Japan
Prior art keywords
group
formula
independently
vii
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63257376A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01143890A (ja
Inventor
アイケ・マイネツベルガー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RUITOHOORUDO UERUKU HEEMITSUSHU FUARUMATSUOICHITSUSHE FUABURIIKU
Original Assignee
RUITOHOORUDO UERUKU HEEMITSUSHU FUARUMATSUOICHITSUSHE FUABURIIKU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RUITOHOORUDO UERUKU HEEMITSUSHU FUARUMATSUOICHITSUSHE FUABURIIKU filed Critical RUITOHOORUDO UERUKU HEEMITSUSHU FUARUMATSUOICHITSUSHE FUABURIIKU
Publication of JPH01143890A publication Critical patent/JPH01143890A/ja
Publication of JPH064667B2 publication Critical patent/JPH064667B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Furan Compounds (AREA)
  • Medicinal Preparation (AREA)
JP63257376A 1987-10-14 1988-10-14 ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法 Expired - Lifetime JPH064667B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3734815.9 1987-10-14
DE19873734815 DE3734815A1 (de) 1987-10-14 1987-10-14 Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel

Publications (2)

Publication Number Publication Date
JPH01143890A JPH01143890A (ja) 1989-06-06
JPH064667B2 true JPH064667B2 (ja) 1994-01-19

Family

ID=6338337

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63257376A Expired - Lifetime JPH064667B2 (ja) 1987-10-14 1988-10-14 ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法

Country Status (13)

Country Link
US (1) US5008247A (tr)
EP (1) EP0312086B1 (tr)
JP (1) JPH064667B2 (tr)
AT (1) ATE101159T1 (tr)
AU (1) AU596755B2 (tr)
CS (1) CS395791A3 (tr)
DE (2) DE3734815A1 (tr)
DK (1) DK162393C (tr)
ES (1) ES2061592T3 (tr)
FI (1) FI89173C (tr)
IE (1) IE63947B1 (tr)
IL (1) IL87936A (tr)
ZA (1) ZA887641B (tr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung
IT1237518B (it) * 1989-11-24 1993-06-08 Renato Conti Eparine supersolfatate
DK0454220T3 (da) * 1990-04-23 1993-11-22 Sanofi Elf Carbohydratderivater omfattende en trisaccharidenhed
US5386018A (en) * 1991-12-31 1995-01-31 Lever Brothers Company, Division Of Conopco, Inc. Process of preparing N-substituted aldonamides
US5714598A (en) * 1993-03-30 1998-02-03 Reliable Biopharmaceutical Corporation Sulfated acid amides having anticoagulant properties
US5589588A (en) * 1993-03-30 1996-12-31 Reliable Biopharmaceutical Corporation Sulfated acid amides having anticoagulant properties
ES2147216T3 (es) * 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
ZA9586B (en) * 1994-01-14 1995-07-20 Hoffmann La Roche New sulfuric acid esters of sugar alochols
TW308598B (tr) * 1994-01-14 1997-06-21 Hoffmann La Roche
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
US5773420A (en) * 1994-11-07 1998-06-30 American Home Products Corporation Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
US5686603A (en) * 1995-05-04 1997-11-11 Lever Brothers Company, Division Of Conopco, Inc. Sulfated polyhydroxy compounds as anionic surfactants and a process for their manufacture
CA2174583A1 (en) * 1995-05-05 1996-11-06 Alexander Chucholowski Sulfuric acid esters of sugar alcohols
CA2174582A1 (en) * 1995-05-05 1996-11-06 Alexander Chucholowski Sulphuric acid esters of amino-sugars
US5849709A (en) * 1995-05-10 1998-12-15 Glycomed Incorporated Saccharopeptides and derivatives thereof
US7081448B2 (en) * 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) * 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US7902158B2 (en) * 2004-08-05 2011-03-08 Ivax Drug Research Ltd. Polysulfated glycosides and salts thereof
GB0622688D0 (en) * 2006-11-14 2006-12-27 Diosamine Dev Corp Novel compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2752334A (en) * 1952-03-01 1956-06-26 Nat Dairy Res Lab Inc Nu-substituted lactobionamides
DE1124938B (de) * 1959-02-05 1962-03-08 Akad Wissenschaften Ddr Verfahren zur Herstellung von nichtionogenen Polyoxycarbonsaeureamiden
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
US4229446A (en) * 1979-03-13 1980-10-21 Kyowa Hakko Kogyo Co., Ltd. Aluminum acetylsalicylate glutaminate
US4357326A (en) * 1981-08-28 1982-11-02 American Cyanamid Company Multi-glucopyranosyl-fructofuranosyl-galactopyranosyl-glucopyranoside sulfate salts and methods of use
DE3204373A1 (de) * 1982-02-09 1983-08-18 Luitpold-Werk, Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München Thiazaspiranderivate, verfahren zu ihrer herstellung und arzneimittel
JPS6261965A (ja) * 1985-09-11 1987-03-18 Kao Corp ビス（２−グルコンアミドアルキル）ジスルフイド
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK572788D0 (da) 1988-10-14
FI884697A0 (fi) 1988-10-12
IE883103L (en) 1989-04-14
AU2368688A (en) 1989-04-20
IE63947B1 (en) 1995-06-28
DE3887618D1 (de) 1994-03-17
FI884697A (fi) 1989-04-15
ZA887641B (en) 1989-07-26
EP0312086A2 (de) 1989-04-19
US5008247A (en) 1991-04-16
FI89173C (fi) 1993-08-25
JPH01143890A (ja) 1989-06-06
ES2061592T3 (es) 1994-12-16
EP0312086B1 (de) 1994-02-02
IL87936A (en) 1993-01-31
DK572788A (da) 1989-04-15
CS395791A3 (en) 1992-09-16
DE3734815C2 (tr) 1990-12-20
AU596755B2 (en) 1990-05-10
EP0312086A3 (de) 1991-07-03
DE3734815A1 (de) 1989-04-27
FI89173B (fi) 1993-05-14
DK162393B (da) 1991-10-21
DK162393C (da) 1992-03-09
IL87936A0 (en) 1989-03-31
ATE101159T1 (de) 1994-02-15

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