JPH064667B2 - ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法 - Google Patents
ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法Info
- Publication number
- JPH064667B2 JPH064667B2 JP63257376A JP25737688A JPH064667B2 JP H064667 B2 JPH064667 B2 JP H064667B2 JP 63257376 A JP63257376 A JP 63257376A JP 25737688 A JP25737688 A JP 25737688A JP H064667 B2 JPH064667 B2 JP H064667B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- independently
- vii
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Furan Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3734815.9 | 1987-10-14 | ||
DE19873734815 DE3734815A1 (de) | 1987-10-14 | 1987-10-14 | Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH01143890A JPH01143890A (ja) | 1989-06-06 |
JPH064667B2 true JPH064667B2 (ja) | 1994-01-19 |
Family
ID=6338337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63257376A Expired - Lifetime JPH064667B2 (ja) | 1987-10-14 | 1988-10-14 | ビス−アルドアミド類のポリ硫酸エステル類およびそれらの誘導体類、それらを製造する方法 |
Country Status (13)
Country | Link |
---|---|
US (1) | US5008247A (tr) |
EP (1) | EP0312086B1 (tr) |
JP (1) | JPH064667B2 (tr) |
AT (1) | ATE101159T1 (tr) |
AU (1) | AU596755B2 (tr) |
CS (1) | CS395791A3 (tr) |
DE (2) | DE3734815A1 (tr) |
DK (1) | DK162393C (tr) |
ES (1) | ES2061592T3 (tr) |
FI (1) | FI89173C (tr) |
IE (1) | IE63947B1 (tr) |
IL (1) | IL87936A (tr) |
ZA (1) | ZA887641B (tr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3734853A1 (de) * | 1987-10-14 | 1989-04-27 | Luitpold Werk Chem Pharm | Bis-aldonsaeureamide und verfahren zu ihrer herstellung |
IT1237518B (it) * | 1989-11-24 | 1993-06-08 | Renato Conti | Eparine supersolfatate |
DK0454220T3 (da) * | 1990-04-23 | 1993-11-22 | Sanofi Elf | Carbohydratderivater omfattende en trisaccharidenhed |
US5386018A (en) * | 1991-12-31 | 1995-01-31 | Lever Brothers Company, Division Of Conopco, Inc. | Process of preparing N-substituted aldonamides |
US5714598A (en) * | 1993-03-30 | 1998-02-03 | Reliable Biopharmaceutical Corporation | Sulfated acid amides having anticoagulant properties |
US5589588A (en) * | 1993-03-30 | 1996-12-31 | Reliable Biopharmaceutical Corporation | Sulfated acid amides having anticoagulant properties |
ES2147216T3 (es) * | 1993-09-01 | 2000-09-01 | Akzo Nobel Nv | Bisconjugados que comprenden dos sacaridos y un grupo de union. |
ZA9586B (en) * | 1994-01-14 | 1995-07-20 | Hoffmann La Roche | New sulfuric acid esters of sugar alochols |
TW308598B (tr) * | 1994-01-14 | 1997-06-21 | Hoffmann La Roche | |
US5565432A (en) * | 1994-11-07 | 1996-10-15 | American Home Products Corporation | Smooth muscle cell proliferation inhibitors |
US5773420A (en) * | 1994-11-07 | 1998-06-30 | American Home Products Corporation | Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation |
US5498775A (en) * | 1994-11-07 | 1996-03-12 | American Home Products Corporation | Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation |
US5686603A (en) * | 1995-05-04 | 1997-11-11 | Lever Brothers Company, Division Of Conopco, Inc. | Sulfated polyhydroxy compounds as anionic surfactants and a process for their manufacture |
CA2174583A1 (en) * | 1995-05-05 | 1996-11-06 | Alexander Chucholowski | Sulfuric acid esters of sugar alcohols |
CA2174582A1 (en) * | 1995-05-05 | 1996-11-06 | Alexander Chucholowski | Sulphuric acid esters of amino-sugars |
US5849709A (en) * | 1995-05-10 | 1998-12-15 | Glycomed Incorporated | Saccharopeptides and derivatives thereof |
US7081448B2 (en) * | 1998-11-24 | 2006-07-25 | Wyeth | Benzyllactobionamides as inhibitors of smooth muscle cell proliferation |
US6664243B1 (en) * | 1998-11-24 | 2003-12-16 | Wyeth | Benzyllactobionamides as inhibitors of smooth muscle cell proliferation |
US6291434B1 (en) | 1998-11-24 | 2001-09-18 | American Home Products Corp. | Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation |
US7132402B2 (en) | 1998-11-24 | 2006-11-07 | Wyeth | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation |
US6258784B1 (en) | 1998-11-24 | 2001-07-10 | American Home Products Corp. | Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation |
US6340670B1 (en) | 1998-11-24 | 2002-01-22 | American Home Products Corporation | Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation |
US6451767B1 (en) | 1998-11-24 | 2002-09-17 | Wyeth | Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation |
US6187755B1 (en) | 1998-11-24 | 2001-02-13 | American Home Products Corporation | Benzylmaltosides as inhibitors of smooth muscle cell proliferation |
AU5706699A (en) * | 1998-11-24 | 2000-06-13 | American Home Products Corporation | Benzyllactobionamides as inhibitors of smooth muscle cell proliferation |
US6362170B1 (en) | 1998-11-24 | 2002-03-26 | American Home Products Corporation | Benzylglycosylamides as inhibitors of smooth muscle cell proliferation |
US6339064B1 (en) | 1998-11-24 | 2002-01-15 | American Home Products Corporation | Benzylglycosylamides as inhibitors of smooth muscle cell proliferation |
US7902158B2 (en) * | 2004-08-05 | 2011-03-08 | Ivax Drug Research Ltd. | Polysulfated glycosides and salts thereof |
GB0622688D0 (en) * | 2006-11-14 | 2006-12-27 | Diosamine Dev Corp | Novel compounds |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2752334A (en) * | 1952-03-01 | 1956-06-26 | Nat Dairy Res Lab Inc | Nu-substituted lactobionamides |
DE1124938B (de) * | 1959-02-05 | 1962-03-08 | Akad Wissenschaften Ddr | Verfahren zur Herstellung von nichtionogenen Polyoxycarbonsaeureamiden |
US4098995A (en) * | 1976-07-12 | 1978-07-04 | American Cyanamid Company | Polygalactosido-sucrose poly(h-)sulfate salts |
US4229446A (en) * | 1979-03-13 | 1980-10-21 | Kyowa Hakko Kogyo Co., Ltd. | Aluminum acetylsalicylate glutaminate |
US4357326A (en) * | 1981-08-28 | 1982-11-02 | American Cyanamid Company | Multi-glucopyranosyl-fructofuranosyl-galactopyranosyl-glucopyranoside sulfate salts and methods of use |
DE3204373A1 (de) * | 1982-02-09 | 1983-08-18 | Luitpold-Werk, Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München | Thiazaspiranderivate, verfahren zu ihrer herstellung und arzneimittel |
JPS6261965A (ja) * | 1985-09-11 | 1987-03-18 | Kao Corp | ビス(2−グルコンアミドアルキル)ジスルフイド |
DE3734853A1 (de) * | 1987-10-14 | 1989-04-27 | Luitpold Werk Chem Pharm | Bis-aldonsaeureamide und verfahren zu ihrer herstellung |
-
1987
- 1987-10-14 DE DE19873734815 patent/DE3734815A1/de active Granted
-
1988
- 1988-10-05 IL IL87936A patent/IL87936A/xx not_active IP Right Cessation
- 1988-10-12 AU AU23686/88A patent/AU596755B2/en not_active Ceased
- 1988-10-12 FI FI884697A patent/FI89173C/fi not_active IP Right Cessation
- 1988-10-12 US US07/256,624 patent/US5008247A/en not_active Expired - Fee Related
- 1988-10-13 IE IE310388A patent/IE63947B1/en not_active IP Right Cessation
- 1988-10-13 ZA ZA887641A patent/ZA887641B/xx unknown
- 1988-10-14 JP JP63257376A patent/JPH064667B2/ja not_active Expired - Lifetime
- 1988-10-14 DK DK572788A patent/DK162393C/da not_active IP Right Cessation
- 1988-10-14 ES ES88117115T patent/ES2061592T3/es not_active Expired - Lifetime
- 1988-10-14 EP EP88117115A patent/EP0312086B1/de not_active Expired - Lifetime
- 1988-10-14 DE DE88117115T patent/DE3887618D1/de not_active Expired - Fee Related
- 1988-10-14 AT AT88117115T patent/ATE101159T1/de not_active IP Right Cessation
-
1991
- 1991-12-20 CS CS913957A patent/CS395791A3/cs unknown
Also Published As
Publication number | Publication date |
---|---|
DK572788D0 (da) | 1988-10-14 |
FI884697A0 (fi) | 1988-10-12 |
IE883103L (en) | 1989-04-14 |
AU2368688A (en) | 1989-04-20 |
IE63947B1 (en) | 1995-06-28 |
DE3887618D1 (de) | 1994-03-17 |
FI884697A (fi) | 1989-04-15 |
ZA887641B (en) | 1989-07-26 |
EP0312086A2 (de) | 1989-04-19 |
US5008247A (en) | 1991-04-16 |
FI89173C (fi) | 1993-08-25 |
JPH01143890A (ja) | 1989-06-06 |
ES2061592T3 (es) | 1994-12-16 |
EP0312086B1 (de) | 1994-02-02 |
IL87936A (en) | 1993-01-31 |
DK572788A (da) | 1989-04-15 |
CS395791A3 (en) | 1992-09-16 |
DE3734815C2 (tr) | 1990-12-20 |
AU596755B2 (en) | 1990-05-10 |
EP0312086A3 (de) | 1991-07-03 |
DE3734815A1 (de) | 1989-04-27 |
FI89173B (fi) | 1993-05-14 |
DK162393B (da) | 1991-10-21 |
DK162393C (da) | 1992-03-09 |
IL87936A0 (en) | 1989-03-31 |
ATE101159T1 (de) | 1994-02-15 |
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