JPH06192061A - Cosmetic - Google Patents

Abstract

PURPOSE:To provide a cosmetic safe to human bodies, free from greasiness on the skin, having both of humectant effect and skin-smoothing effect, also excellent in skin-beautifying, ultraviolet light absorbing and skin aging-preventive effects. CONSTITUTION:This cosmetic consists of intact water extract or organic solvent extract of rice or a material containing such extracts. The cosmetic can be obtained by the following process: rice is crushed or ground into powder; water is added thereto followed by heating to boil; or at first, hot water is added thereto and carried out to extract to obtain a water extract, which is, if desired, put to squeezing and filtration to obtain a clear extract. An organic solvent (pref. to be safe even if administered to human bodies, e.g. ethyl alcohol) may be used in place of hot water and the extract exhibits a comparable effect.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention is a cosmetic comprising a water extract or an organic solvent extract from rice as it is or containing it, which has an excellent moisturizing effect on human skin and is slippery. The present invention relates to cosmetics that not only have the same effects, but also have excellent whitening effects, ultraviolet absorbing effects, and anti-aging effects.

[0002]

2. Description of the Related Art Conventionally, cosmetics have been mixed mainly with oils, amino acids and polysaccharides to provide moisturizing properties. More recently, safety of cosmetics has become a problem, and natural oils, hyaluronic acid, and natural moisturizers such as placenta extract have been developed, but they have drawbacks such as stickiness. However, it is the current situation that the effect of smoothing the skin is not clearly known. In addition, recently, cosmetics with added value such as whitening cosmetics containing koji acid and UV cosmetics containing an ultraviolet absorber or an ultraviolet blocking agent have been released, but they are natural and have a moisturizing effect (moisturizing effect). )
It has a remarkable effect on the skin, and has a remarkable effect of smoothing the skin.
Moreover, a cosmetic having a whitening effect, an ultraviolet absorbing effect and an anti-aging effect has not yet been known.

On the other hand, rice has been developed as a staple food, as well as sake, shochu, amazake, mirin, vinegar, koji, etc., and has been indispensable for life since ancient times. In addition to this, bran bags are known for cosmetic purposes. These are believed to be due to the fact that rice was viewed as merely a staple food, or at best, as a source of starch. Moreover, even if the rice bran is used, it is said that it is good for the skin, and it has been customarily used as it is, and there was no concept of an active ingredient and no idea of extraction.

[0004]

At present, the safety of the human body in cosmetics is also a problem, and in addition, the pursuit of added value such as whitening, stain removal, anti-aging (wrinkle removal), and wrinkle removal has been pursued. There is. Therefore, it is safe for the human body, has no stickiness to the skin, and also has a moisturizing effect (moisturizing effect) and a smoothing effect on the skin, and also has a whitening effect, an ultraviolet absorbing effect, and an anti-aging effect. There is a demand for cosmetics that are also excellent.

[0005]

[Means for Solving the Problems] From the viewpoint of animal and plant harmony, the present inventors have conducted research on various plant components centering on rice, which is a staple food. In the process, it has become clear that rice has many unpredictable possibilities and effects. Therefore, we have conducted a comprehensive utilization study of rice, focusing on rice, which is used as a staple food and has been demonstrated to have the highest safety.

[0006] As one of the themes, intensive research has been conducted on cosmetics from rice. In the process, when the rice extract was applied to the skin as it was or when it contained it, it not only has a moisturizing effect and a smooth effect, but also has excellent whitening effect, ultraviolet absorbing effect, and anti-aging effect. Therefore, the present invention has been completed.

That is, the present invention is a cosmetic comprising a water extract or an organic solvent extract from rice as it is or containing it, wherein the rice is extracted with water (acid, alkali extraction). It is also possible to obtain a very excellent cosmetic product which exhibits the above effects simply, inexpensively and completely safely by extraction with an organic solvent such as alcohol).

When the extraction operation of the present invention is performed, first, if rice is pulverized or pulverized, the surface area is increased, so that the extraction efficiency is improved. This method may be a general method using a crusher or a rice mill. Although it is not necessary to grind, in this case, it takes a long time to decompose and extract the rice tissue.

In the water extraction, rice is hydrated as it is, preferably crushed or powdered. The rice may be brown rice or white rice. About the amount of water, 2 to rice
It is efficiently extracted in a 5-fold amount, but may be appropriately selected depending on the yield, workability, purpose of final use and the like. Then, the mixture is heated and the extraction is completed at the time of boiling. After completing the extraction, if you squeeze and filter according to the purpose of use,
A clear extract is obtained. Note that hot water may be added from the beginning to perform extraction.

Regarding the extraction temperature in water extraction, although the active ingredient in the extract has not been clarified, it has been confirmed that this unknown active ingredient is stable to heat, so high temperature is efficient. If it is left at a low temperature for a long time, it can be sufficiently extracted. However, at a low temperature of 40 ° C. or lower, it is necessary to make the pH acidic or alkaline or to add a preservative. The extraction time may be a few minutes in the case of boiling extraction, but if the temperature is lower than that, several hours to one day is required. When the temperature is low, it takes several days to one month depending on the crushed state of rice. However, even in this case, it is more effective to heat at the end as much as possible.

In the case of water extraction, the most problematic is the gelatinization phenomenon. If it becomes pasty, not only the extraction efficiency will deteriorate, but it will be extremely difficult in actual work. In order to prevent this, the reaction may be carried out by adding amylase or by acidifying with hydrochloric acid or the like to decompose the starch. By using this method, it can be sufficiently solved and there is no problem in practice.

Since the active ingredient in the extract is stable to acid and alkali, acid extraction or alkali extraction is also effective. Further, in the case of water extraction, a method of pre-treating with an acid or alkali or reacting with an enzyme (for example, amylase) that acts on the tissue of rice to perform pre-treatment and extracting is effective. This is probably because the pretreatment makes it easier for the active ingredient to be extracted.

Furthermore, it has been found that an extract having this effect can be extracted even by extraction with an organic solvent. This is extremely effective in advancing the elucidation of the active ingredient, and also in the usage such as extracting the active ingredient into a concrete or blending with an insoluble substance. In this case, it is preferable to pulverize or pulverize as much as possible. The organic solvent used here is preferably alcohol, such as alcohol, which is safe to administer to the human body.

It is more effective to extract the product of the present invention from rice by organic solvent extraction or water extraction as described above and further solvent extraction of the active ingredient in the extract. However, this is probably because the concentrated state is obtained, and the same effect can be obtained by concentrating. In addition, depending on the application, the presence of sugar may cause stickiness or hinder the effect. In that case, the sugar may be removed by feeding the sugar to yeast, fractionating the active ingredient with an adsorbent, or extracting with an organic solvent. In any case, the effect can be obtained by performing extraction, so that unnecessary components may be removed by various methods depending on the application. Furthermore, the same effect was obtained by combining the extract with fermentation such as alcoholic fermentation and lactic acid fermentation.

Since rice is eaten every day as a staple food, it was so close to us that there was no concept of using it as a cosmetic, and it was unexpected. Also, it has been used for sake, shochu, vinegar, etc. other than eating, but the idea and method of extracting rice have not been taken. This may be due to the fact that when rice is extracted by heating, it becomes pasty as a characteristic of rice, which is very difficult in the conventional way of thinking. Therefore, in the present invention, organic solvent, extraction,
Acid or alkali extraction is used, and in the case of water extraction, by making amylase etc. act to facilitate extraction,
It made it possible to achieve the purpose.

It is possible to extract an extremely effective active ingredient as a cosmetic only after performing sufficient extraction operation in this manner, and the specific effect thereof will be described based on experimental results. First, in order to demonstrate the strength of the moisturizing effect of the product of the present invention as data, a single coating test was conducted using a moisture meter (SKICON 200). Room temperature 20 as measurement condition
The environment was set to 65 ° C. and 65% relative humidity, and the panelists were allowed to rest in the above environment for about 10 minutes before the measurement. The test site (both sides) was selected on the flexion side of the forearm where no rash was observed. The panelists were 5 people.

Main test (using the product of the present invention obtained in Example 1) read from a moisture meter and control test (using water)
The average values of changes in the water content of the stratum corneum are shown in FIG. 1
The measurement method of the repeated application test is as follows.

Measurement method 1) A test site of 5 × 5 cm and a control site are set on the forearm flexion side of the panel. 2) Measure the water content of the stratum corneum at each site. 3) Measure the water content of the stratum corneum immediately after coating the sample and after 30, 60, 90 and 120 minutes.

From FIG. 1, in the test site to which the product of the present invention was applied, the horny layer water content immediately after application was about 13% of that of the control.
A doubling increase was observed. Also, 30 minutes after application 1
When viewed up to 20 minutes, it can be seen that the application site of the present invention maintains the water content 2 to 3 times that of the control. From this, it was revealed that the product of the present invention has an extremely excellent moisturizing effect.

Next, the effects of smooth skin and fine texture were illustrated. As a test method, the product of the present invention was applied to the right arm site of a panelist twice a day for one month, and the site of application of the product of the present invention was measured by a dynamic friction meter. The same part of the left arm was used as a control. The panelists were 6 people. The measurement conditions are as follows.

Temperature 25 ° C Humidity 60% Sensor used KES-SE Friction tester SE-2 type (0.5mm piano wire used) Friction / static load 50gf Measuring speed 1mm / sec Measuring distance 30mm (effective integration range 20mm)

The results are shown in FIGS. 2 and 3. As shown in FIG. 2, in the part of the left arm not coated with the product of the present invention,
The MMD (coefficient of variation) of 0.0172 decreased to MMD (coefficient of variation) of 0.0042 in the part of the right arm to which the product of the present invention was applied for one month, as shown in FIG. The average values of 6 persons were almost the same. It is considered that this is because the fluctuation due to the unevenness of the surface became smaller, and from this,
It turned out that the texture of the skin became finer. At the same time, when MIU (friction coefficient) was examined, it was 0.12 before coating.
It was 3 but the skin after applying for 1 month dropped to 0.073, and it was also found to have the effect of making the skin smooth.

Further, the absorption spectrum of the product of the present invention was measured in order to exemplify the ultraviolet absorption effect of the product of the present invention by data. The results are shown in Fig. 4. From FIG. 4, it can be seen that the product of the present invention has a UVB region of 280 to 320 nm and a wavelength of 320 to 320 nm.
Low wavelength region of UVA of 380 nm (about 320 to 3
It was found that the absorption effect was excellent at 40 nm).

Since the product of the present invention has sufficient absorption only in the UVB region, it may be considered that the effect is not sufficient, but the shortest wavelength of ultraviolet rays reaching the surface of the earth is 295.
In terms of nm, the longest wavelength is said to be 320 to 330 nm, and therefore, it can be said that the ultraviolet absorption capacity is substantially sufficient. In addition, this is approximately three times as high as the absorbency of the natural herb extracts and natural herb ingredients (oil-soluble licorice extract P-U, lycochalcone A, baicalein, γ-oryzanol, etc.) that have natural ultraviolet absorption capacity. . Also from this, it was proved that the product of the present invention has an excellent ultraviolet absorbing ability. Furthermore, in order to illustrate the whitening effect of the present invention,
The tyrosinase activity inhibitory effect was tested.

As the operation method, a substrate solution (0.04% tyrosine solution) and a buffer solution (Mcllvaine Buffer pH6.
8) Accurately take 1 ml of each in an absorption cell, and mix with water and Example 1
Accurately put 1 ml of the product of the present invention obtained in
After stirring and mixing at 35 ° C. for 5 minutes, the absorbance scale was adjusted to zero at 475 nm, and then the tyrosinase solution (5.3 mg of tyrosinase was added to 0.9% NaCl).
0.02 ml (dissolved in the solution) was accurately added, and the mixture was immediately stirred and incubated. The absorbance at this time was measured over time (every 3 minutes) and is shown in Table 1.

[0026]

[Table 1]

As can be seen from Table 1, the product of the present invention was found to have a tyrosinase activity inhibitory action. From this, it can be said that the product of the present invention has a whitening effect. next,
In order to examine the effect of rejuvenating the skin, six female monitors aged 70 to 80 were applied with the product of the present invention on the back of the hand for one week, and the place was sampled by the sump method. A comparison was made with skin not using the invention product.

As shown in FIG. 5, in the skin of a 21-year-old female monitor, not only the sulcus 1 is clearly recognized in multiple directions, but also the skin crest (turtle shell pattern) 2 is clearly shown. However, as shown in FIG. 6, in the 71-year-old monitor, only the unidirectional cutaneous groove 1 ′ was observed, and no cuticle was observed at all. It is said that the skin loses elasticity as it grows older, and the skin groove becomes shallower due to its tightness, and the cuticles gradually disappear.

However, when the product of the present invention was applied for 1 week, as shown in FIG. 7, the skin groove 1'which was observed only in one direction before use was clearly recognized in multiple directions. It was Not only that, but even the skin mounds (turtle shell pattern) 2'which were not seen at all before application became clearly visible, almost no substitute for the skin of a 21-year-old woman. In addition, in terms of feel, elasticity was improved, and a rejuvenating effect was recognized. This phenomenon was similarly observed in the remaining 5 monitors. It can be said that, by using the product of the present invention, the original function of the skin is directed to the recovery direction, and a clear and regular skin pattern appears.
From this, it was demonstrated that the product of the present invention has a clear rejuvenating effect.

Next, in order to demonstrate the anti-aging effect, 4
The present invention product was continuously used on the back of the hand by three female monitors in their 0's for one week, and microscopic observation by the Sump method was performed.
As the product of the present invention, the product obtained according to Example 1 was used.

As shown in FIG. 8, in the skin not coated with the product of the present invention, only the skin groove 3 in one direction is conspicuous, and the skin groove 3'orthogonal to the skin groove is indistinct. As shown in FIG. 9, the skin in which the product of the present invention was continuously used for one week exhibited not only the unclear skin groove 3'clearly but also a fine skin groove. This phenomenon similarly appeared on the other two monitors. From this, it was demonstrated that the product of the present invention also has an effect of helping to prevent skin aging. Furthermore, when the skin to which the product of the present invention was continuously applied for one month was observed, the effect was further recognized.

Next, the effectiveness of the product of the present invention in actual use was examined. First, 15 panelists were continuously coated with the product of the present invention obtained in Example 1 twice a day for one month, and the effectiveness in actual use was examined.

As a result, 12 out of 15 persons were said to have an effect of clearing the skin. Also, for the remaining three people, the background was originally white,
He said that the effect was not clear. However, everyone said that the skin seemed to be moist and smooth, and that the texture of the skin had become smooth. As a result, it was found that even in actual use, a clear effect was obtained, and it was found that it has a very excellent effect as a cosmetic.

[0034]

As can be seen from the above results, by extracting rice with water or an organic solvent, it is possible to easily and completely safely moisturize and smooth the skin, and to keep the texture of the skin. A very excellent cosmetic having a whitening effect, an ultraviolet absorbing effect, and an anti-aging effect was obtained.

Since rice has been the staple food until now, new production methods and uses have hardly been developed. Furthermore, rice has been the staple food until now, and its safety has been proven. That is, the present invention not only has a very excellent effect as a cosmetic,
We have found that the safety has been well verified, and can be said to be a very meaningful invention that can be used in various cosmetics.

In addition, as it is said that rice is overproduced,
Finding new uses for rice and expanding consumption by improving the image of rice are extremely significant.

[0037]

EXAMPLES Next, examples of the present invention will be described. Example 1 15 kg of white rice was crushed well, 45 liters of warm water at 60 ° C and 50 g of liquefied enzyme were added thereto, and the mixture was stirred well. afterwards,
Gradually raise the temperature, boil and extract for 5 minutes, then 30
Cooled to ° C. Then, it squeezed with a squeezing machine to obtain 41 liters of the product of the present invention and 16 kg of residue.

Example 2 1 kg of white rice was well pulverized, 5 liters of 0.1% hydrochloric acid water was well added, well stirred, and left for 6 hours. Then, it was squeezed with a squeezing machine to separate 4.6 liters of compressed liquid and 1.2 kg of residue. This compressed liquid was neutralized with 1N NaOH to obtain 4.7 liters of the product of the present invention.

Example 3 1 kg of white rice was well pulverized, 3 liters of 95% alcohol was added, and the mixture was well stirred and allowed to stand. Four days later, the product was squeezed with a squeezing machine to obtain 2.5 liters of the pressing liquid and 1.2 kg of the residue. One part of this squeezed liquid was added with 500 ml of water, and alcohol was completely removed by a rotary evaporator to obtain 480 ml of the product of the present invention.

[Procedure amendment]

[Submission date] November 26, 1992

[Procedure Amendment 1]

[Document name to be amended] Statement

[Name of item to be corrected] Brief description of the drawing

[Correction method] Added

[Correction content]

[Brief description of drawings]

FIG. 1 shows a moisture meter (S
It is a graph which shows the result of having performed the coating test once using KICON200).

FIG. 2 is a graph showing the results of measuring the skin not coated with the product of the present invention with a dynamic friction meter.

FIG. 3 is a graph showing the results of measurement of the skin to which the product of the present invention was applied twice a day for one month, using a dynamic friction meter.

FIG. 4 is a graph showing a result of measuring an absorption spectrum regarding an ultraviolet absorption effect of the product of the present invention.

FIG. 5 is a micrograph of a sump image obtained by collecting the skin of a 21-year-old female monitor by the sump method.

FIG. 6 is a micrograph of a sump image obtained by collecting the skin of a 71-year-old female monitor by the sump method.

FIG. 7 is a photomicrograph of a sump image obtained by the sump method on the skin of a 71-year-old female monitor who was applied with the product of the present invention for one week.

FIG. 8 is a micrograph of a sump image obtained by collecting the skin of a 40-year-old female monitor by the sump method.

FIG. 9 is a photomicrograph of a sump image obtained by the sump method on the skin of a 40-year-old female monitor who was applied with the product of the present invention for one week.

Claims (1)

[Claims] 1. A cosmetic comprising a water extract or an organic solvent extract from rice as it is or containing the same.