JPH06100532A - ３−置換−２−アゼチジノンの製造方法 - Google Patents

３−置換−２−アゼチジノンの製造方法

Info

Publication number
JPH06100532A
JPH06100532A JP5060054A JP6005493A JPH06100532A JP H06100532 A JPH06100532 A JP H06100532A JP 5060054 A JP5060054 A JP 5060054A JP 6005493 A JP6005493 A JP 6005493A JP H06100532 A JPH06100532 A JP H06100532A
Authority
JP
Japan
Prior art keywords
alkyl
formula
phenyl
substituted
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5060054A
Other languages
English (en)
Japanese (ja)
Inventor
Catherine M Gasparski
キャサリン・メアリー・ガスパルスキ
Marvin J Miller
マービン・ジョゼフ・ミラー
Min Teng
ミン・テン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Notre Dame
Original Assignee
University of Notre Dame
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Notre Dame filed Critical University of Notre Dame
Publication of JPH06100532A publication Critical patent/JPH06100532A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/12—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP5060054A 1992-03-23 1993-03-19 ３−置換−２−アゼチジノンの製造方法 Pending JPH06100532A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/855,402 US5250676A (en) 1992-03-23 1992-03-23 Process for the preparation of 3-substituted-2-azetidinones
US855402 1992-03-23

Publications (1)

Publication Number Publication Date
JPH06100532A true JPH06100532A (ja) 1994-04-12

Family

ID=25321177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5060054A Pending JPH06100532A (ja) 1992-03-23 1993-03-19 ３−置換−２−アゼチジノンの製造方法

Country Status (4)

Country Link
US (1) US5250676A (show.php)
EP (1) EP0564129A2 (show.php)
JP (1) JPH06100532A (show.php)
CA (1) CA2091977A1 (show.php)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020087500A (ko) * 2000-12-23 2002-11-23 주식회사대웅제약 3-치환 아제티디논의 제조방법
JP2017067779A (ja) * 2015-09-30 2017-04-06 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 検体の誘導体化及び向上したソフトイオン化の方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2590429B2 (ja) * 1994-03-08 1997-03-12 工業技術院長 β‐ラクタム誘導体及びその製造方法
US5750681A (en) * 1995-06-19 1998-05-12 University Of Notre Dame Du Lac Bicyclic beta-lactams and process therefor
WO2013007371A2 (en) * 2011-07-13 2013-01-17 Eth Zurich Kinetic resolution of chiral amines
US9862680B2 (en) * 2016-06-13 2018-01-09 University Of Notre Dame Du Lac Peripherally substituted monocyclic beta-lactams
WO2019070672A1 (en) * 2017-10-05 2019-04-11 University Of Notre Dame Du Lac ANTIBACTERIAL MONOBACTERAMES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ228600A (en) * 1988-04-11 1992-02-25 Merck & Co Inc 1-(benzylaminocarbonyl)-4-phenoxy-azetidin-2-one derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020087500A (ko) * 2000-12-23 2002-11-23 주식회사대웅제약 3-치환 아제티디논의 제조방법
JP2017067779A (ja) * 2015-09-30 2017-04-06 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 検体の誘導体化及び向上したソフトイオン化の方法

Also Published As

Publication number Publication date
EP0564129A2 (en) 1993-10-06
US5250676A (en) 1993-10-05
CA2091977A1 (en) 1993-09-24
EP0564129A3 (show.php) 1994-04-13

Similar Documents

Publication Publication Date Title
US5561227A (en) Process for the stereospecific synthesis of azetidinones
US4595532A (en) N-(substituted-methyl)-azetidin-2-ones
US5767316A (en) Process for producing 3-amino-2-oxo-1-halogenopropane derivatives
KR950013767B1 (ko) 키랄성 아제티디논 화합물 및 이의 제조방법
JPH06100532A (ja) ３−置換−２−アゼチジノンの製造方法
Maciejewski et al. An approach to carbapenems from α, β-unsaturated sugar lactones
WO2019131695A1 (ja) １－［５－（２－フルオロフェニル）－１－（ピリジン－３－イルスルホニル）－１ｈ－ピロ－ル－３－イル］－ｎ－メチルメタンアミンモノフマル酸塩の製造法
CN102131802A (zh) 用作凝血酶抑制剂的新型杂环甲酰胺
WO2017144015A1 (zh) 一种新毒素及其中间体的制备方法
US5650518A (en) Protected aminothiazolylacetic acid derivatives
JP3505241B2 (ja) １Ｈ−１，２，４−トリアゾール誘導体及び１Ｈ−ピロロ−〔１，２−ｂ〕〔１，２，４〕トリアゾール誘導体
JPS6023363A (ja) Ｎ−（置換メチル）−アゼチジン−２−オン類
US4992545A (en) Process for preparing 4-substituted azetidinones
PL114624B1 (en) Process for preparing novel cephem derivatives
EP0064797B1 (en) N-diarylmethyl-3-amino-4-alkenaryl-2-azetidinones and their preparation
JPH0641066A (ja) ピロール誘導体の製造方法
JP2620533B2 (ja) 新規なアミノ酸誘導体
JPH0479333B2 (show.php)
FR2758326A1 (fr) Derives de pyridone, leur prepaparation et leur utilisation comme intermediaires de synthese
JPH08325265A (ja) チアゾリルベンゾフラン誘導体の製造方法、および該製造方法に用いられる化合物
US5106475A (en) Process for preparing 4-substituted azetidinones
JP2652047B2 (ja) ４−ベンゾイルオキシ−３−ヒドロキシエチルアゼチジン−２−オン誘導体の製造方法
JP2733256B2 (ja) ４−メルカプトピラゾリジン誘導体
JPH083132A (ja) プロリルプロリン誘導体及びその新規な製造法
JP3386452B2 (ja) 場合により保護基をもつ３−ヒドロキシメチルカルバペネム及び合成