JPH057996B2 - - Google Patents
Info
- Publication number
- JPH057996B2 JPH057996B2 JP18730384A JP18730384A JPH057996B2 JP H057996 B2 JPH057996 B2 JP H057996B2 JP 18730384 A JP18730384 A JP 18730384A JP 18730384 A JP18730384 A JP 18730384A JP H057996 B2 JPH057996 B2 JP H057996B2
- Authority
- JP
- Japan
- Prior art keywords
- ifn
- dna
- protein
- cysteine
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43515482A | 1982-10-19 | 1982-10-19 | |
| US435154 | 1982-10-19 | ||
| US486162 | 1983-04-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6128384A JPS6128384A (ja) | 1986-02-08 |
| JPH057996B2 true JPH057996B2 (es) | 1993-01-29 |
Family
ID=23727220
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58195931A Granted JPS5993093A (ja) | 1982-10-19 | 1983-10-19 | 変形されたインターロイキン―２及びその製造方法 |
| JP18730284A Granted JPS6128393A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
| JP18730484A Pending JPS6128394A (ja) | 1982-10-19 | 1984-09-08 | 部位特定突然変異用オリゴヌクレオチド |
| JP18730384A Granted JPS6128384A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58195931A Granted JPS5993093A (ja) | 1982-10-19 | 1983-10-19 | 変形されたインターロイキン―２及びその製造方法 |
| JP18730284A Granted JPS6128393A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
| JP18730484A Pending JPS6128394A (ja) | 1982-10-19 | 1984-09-08 | 部位特定突然変異用オリゴヌクレオチド |
Country Status (4)
| Country | Link |
|---|---|
| JP (4) | JPS5993093A (es) |
| IL (1) | IL90047A (es) |
| IN (1) | IN161992B (es) |
| ZA (1) | ZA837789B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL76360A0 (en) | 1984-09-26 | 1986-01-31 | Takeda Chemical Industries Ltd | Mutual separation of proteins |
| JP2675294B2 (ja) * | 1984-10-15 | 1997-11-12 | カイロン コーポレイション | ヒト腫瘍壊死因子 |
| EP0200748B1 (en) * | 1984-10-15 | 1991-02-06 | Cetus Corporation | Human tumor necrosis factor |
| US4572798A (en) * | 1984-12-06 | 1986-02-25 | Cetus Corporation | Method for promoting disulfide bond formation in recombinant proteins |
| JP2721854B2 (ja) * | 1984-12-21 | 1998-03-04 | 大塚製薬株式会社 | 抗腫瘍活性物質 |
| JP2583753B2 (ja) * | 1984-12-21 | 1997-02-19 | 大塚製薬株式会社 | 抗腫瘍活性物質およびその製造法 |
| IL78571A (en) * | 1985-04-22 | 1991-06-30 | Genentech Inc | Human tissue plasminogen activator mutants resistant to enzymatic cleavage resulting in two-chain form |
| US4818698A (en) * | 1985-08-23 | 1989-04-04 | Toyo Jozo Co., Ltd. | Polypeptides and preparation process thereof |
| NZ226543A (en) * | 1987-10-22 | 1992-02-25 | Merck & Co Inc | Recombinant mutant acidic fibroblast growth factor |
| ATE133993T1 (de) * | 1989-02-17 | 1996-02-15 | Merck & Co Inc | Protein-antikrebsmittel |
| NZ232900A (en) * | 1989-03-22 | 1993-08-26 | Merck & Co Inc | Pseudomonas exotoxin a, pe 40 domain derivatives |
| US6207798B1 (en) | 1989-08-03 | 2001-03-27 | Merck & Co., Inc. | Modified PE40 toxin fusion proteins |
| JPH0751621A (ja) * | 1993-08-12 | 1995-02-28 | Kansei Kogyo Kk | 静電吸着による管内面更生工法 |
| AR034749A1 (es) * | 2001-07-09 | 2004-03-17 | Schering Ag | Formulaciones de interferon beta humano |
| BRPI0412477A (pt) * | 2003-07-11 | 2006-09-19 | Schering Ag | aperfeiçoados polipeptìdeos de interferon-beta-1b recombinantes humanos |
-
1983
- 1983-10-14 IL IL90047A patent/IL90047A/xx not_active IP Right Cessation
- 1983-10-19 IN IN1282/CAL/83A patent/IN161992B/en unknown
- 1983-10-19 ZA ZA837789A patent/ZA837789B/xx unknown
- 1983-10-19 JP JP58195931A patent/JPS5993093A/ja active Granted
-
1984
- 1984-09-08 JP JP18730284A patent/JPS6128393A/ja active Granted
- 1984-09-08 JP JP18730484A patent/JPS6128394A/ja active Pending
- 1984-09-08 JP JP18730384A patent/JPS6128384A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IN161992B (es) | 1988-03-12 |
| JPS6128384A (ja) | 1986-02-08 |
| JPS5993093A (ja) | 1984-05-29 |
| JPS6357440B2 (es) | 1988-11-11 |
| ZA837789B (en) | 1984-11-28 |
| JPS6128393A (ja) | 1986-02-08 |
| IL90047A (en) | 1992-12-01 |
| JPS6128394A (ja) | 1986-02-08 |
| JPH0380475B2 (es) | 1991-12-25 |
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