JPH0574576B2 - - Google Patents

Info

Publication number
JPH0574576B2
JPH0574576B2 JP59198899A JP19889984A JPH0574576B2 JP H0574576 B2 JPH0574576 B2 JP H0574576B2 JP 59198899 A JP59198899 A JP 59198899A JP 19889984 A JP19889984 A JP 19889984A JP H0574576 B2 JPH0574576 B2 JP H0574576B2
Authority
JP
Japan
Prior art keywords
gel
sulfate
lpf
crosslinked
cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59198899A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6176422A (ja
Inventor
Akihiro Ginnaga
Mitsuo Sako
Hisashi Kitagawa
Susumu Sakuma
Hiroshi Kiba
Tsukasa Nishihara
Sadahiro Hirashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Priority to JP59198899A priority Critical patent/JPS6176422A/ja
Priority to AU42459/85A priority patent/AU568743B2/en
Priority to AT85106303T priority patent/ATE61230T1/de
Priority to DE8585106303T priority patent/DE3581993D1/de
Priority to EP85106303A priority patent/EP0175841B1/en
Priority to CA000482469A priority patent/CA1239345A/en
Priority to KR1019850003773A priority patent/KR920009730B1/ko
Publication of JPS6176422A publication Critical patent/JPS6176422A/ja
Publication of JPH0574576B2 publication Critical patent/JPH0574576B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP59198899A 1984-05-30 1984-09-22 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法 Granted JPS6176422A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP59198899A JPS6176422A (ja) 1984-09-22 1984-09-22 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法
AU42459/85A AU568743B2 (en) 1984-09-22 1985-05-14 Pertussis vaccine
AT85106303T ATE61230T1 (de) 1984-09-22 1985-05-22 Verfahren zur herstellung einer keuchhustenimpfstoffkomponente und kombinierter impfstoff,bestehend aus keuchhustenantigen diphterietoxoid und tetanustoxoid.
DE8585106303T DE3581993D1 (de) 1984-09-22 1985-05-22 Verfahren zur herstellung einer keuchhusten-impfstoffkomponente und kombinierter impfstoff,bestehend aus keuchhustenantigen diphterietoxoid und tetanustoxoid.
EP85106303A EP0175841B1 (en) 1984-09-22 1985-05-22 Method for the production of pertussis component vaccine and combined vaccine of pertussis antigen; diphtheria toxoid and tetanus toxoid
CA000482469A CA1239345A (en) 1984-09-22 1985-05-27 Method for the production of pertussis component vaccine and combined vaccine of pertussis antigen, diphtheria toxoid and tetanus toxoid
KR1019850003773A KR920009730B1 (ko) 1984-05-30 1985-05-30 백일해 성분 백신 및 백일해 항원, 디프테리아 톡소이드 및 파상풍 톡소이드의 혼합백신의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59198899A JPS6176422A (ja) 1984-09-22 1984-09-22 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法

Publications (2)

Publication Number Publication Date
JPS6176422A JPS6176422A (ja) 1986-04-18
JPH0574576B2 true JPH0574576B2 (esLanguage) 1993-10-18

Family

ID=16398788

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59198899A Granted JPS6176422A (ja) 1984-05-30 1984-09-22 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法

Country Status (7)

Country Link
EP (1) EP0175841B1 (esLanguage)
JP (1) JPS6176422A (esLanguage)
KR (1) KR920009730B1 (esLanguage)
AT (1) ATE61230T1 (esLanguage)
AU (1) AU568743B2 (esLanguage)
CA (1) CA1239345A (esLanguage)
DE (1) DE3581993D1 (esLanguage)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1237998A (en) * 1984-04-14 1988-06-14 Akihiro Ginnaga Method for purification of filamentous hemagglutinin
FR2597605B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Nouveau materiau pour chromatographie d'affinite et son application a la separation et a la purification des antigenes proteiques des bacteries du genre bordetella
EP0267998A1 (en) * 1986-11-17 1988-05-25 Institut Pasteur Means for protecting against bordetella infections and toxic processes
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
US5139776A (en) * 1987-04-24 1992-08-18 The Research Foundation For Microbial Diseases Of Osaka University Method for culturing Bordetella pertussis, a pertussis toxoid and a pertussis vaccine
GB8807860D0 (en) * 1988-04-05 1988-05-05 Connaught Lab Pertussis vaccine
JP2849632B2 (ja) * 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
CA1341123C (en) * 1988-10-27 2000-10-17 David A. Relman Filamentous hemagglutinin of b. pertussis
GB8910570D0 (en) * 1989-05-08 1989-06-21 Wellcome Found Acellular vaccine
IT1248735B (it) * 1990-06-21 1995-01-26 Sclavo Spa Vaccini acellulari contro la pertosse
IL98715A0 (en) * 1990-08-13 1992-07-15 American Cyanamid Co Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines
DE69531690T2 (de) * 1994-06-10 2004-07-08 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Reinigungsverfahren für von bordetella bronchiseptica produziertes dermonekrotisches toxin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247452A (en) * 1978-03-01 1981-01-27 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Purification of pertussis haemagglutinins
US4500639A (en) * 1981-10-15 1985-02-19 Teijin Limited Culturing Bordetella in media containing etherified cyclodextrin
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
CA1237998A (en) * 1984-04-14 1988-06-14 Akihiro Ginnaga Method for purification of filamentous hemagglutinin
KR890001003B1 (ko) * 1984-07-19 1989-04-18 자이단 호오진 까가꾸 오요비 겟세이 료오호 겐뀨쇼 Lpf-ha의 정제방법

Also Published As

Publication number Publication date
DE3581993D1 (de) 1991-04-11
AU4245985A (en) 1986-03-27
EP0175841A3 (en) 1987-08-19
KR920009730B1 (ko) 1992-10-22
EP0175841A2 (en) 1986-04-02
EP0175841B1 (en) 1991-03-06
KR860002570A (ko) 1986-04-26
ATE61230T1 (de) 1991-03-15
JPS6176422A (ja) 1986-04-18
CA1239345A (en) 1988-07-19
AU568743B2 (en) 1988-01-07

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term