JPH0564635B2 - - Google Patents

Info

Publication number
JPH0564635B2
JPH0564635B2 JP60078215A JP7821585A JPH0564635B2 JP H0564635 B2 JPH0564635 B2 JP H0564635B2 JP 60078215 A JP60078215 A JP 60078215A JP 7821585 A JP7821585 A JP 7821585A JP H0564635 B2 JPH0564635 B2 JP H0564635B2
Authority
JP
Japan
Prior art keywords
hydrogen
formula
alkyl
cyano
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60078215A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60231674A (ja
Inventor
Anne Ashutsudo Barerii
Morisu Ebansu Jon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of JPS60231674A publication Critical patent/JPS60231674A/ja
Publication of JPH0564635B2 publication Critical patent/JPH0564635B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP60078215A 1984-04-14 1985-04-12 クロマン誘導体、その製法およびそれを含む医薬組成物 Granted JPS60231674A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8409745 1984-04-14
GB848409745A GB8409745D0 (en) 1984-04-14 1984-04-14 Active compounds

Publications (2)

Publication Number Publication Date
JPS60231674A JPS60231674A (ja) 1985-11-18
JPH0564635B2 true JPH0564635B2 (enExample) 1993-09-16

Family

ID=10559662

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60078215A Granted JPS60231674A (ja) 1984-04-14 1985-04-12 クロマン誘導体、その製法およびそれを含む医薬組成物

Country Status (5)

Country Link
US (1) US4616021A (enExample)
EP (1) EP0158923B1 (enExample)
JP (1) JPS60231674A (enExample)
DE (1) DE3584639D1 (enExample)
GB (1) GB8409745D0 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0205292B1 (en) * 1985-06-08 1991-11-06 Beecham Group Plc Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them
IL88035A0 (en) * 1987-10-27 1989-06-30 American Home Prod Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
CA1308108C (en) * 1987-10-27 1992-09-29 Dominick A. Quagliato Antihypertensive benzopyran derivatives
PT93725A (pt) * 1989-04-12 1990-11-20 American Home Prod Processo para a preparacao de derivados de benzopirano anti-hipertensivos
US4908378A (en) * 1989-04-12 1990-03-13 American Home Products Corporation Benzopyran derivatives and antihypertensive use thereof
US4983612A (en) * 1989-10-05 1991-01-08 American Home Products Corporation Antihypertensive benzopyran derivatives
GB9002458D0 (en) * 1990-02-03 1990-04-04 Beecham Group Plc Pharmaceuticals
US5252597A (en) * 1990-03-29 1993-10-12 American Home Products Corporation Antihypertensive benzopyran derivatives
US5171857A (en) * 1990-03-29 1992-12-15 American Home Products Corporation Antihypertensive benzopyran derivatives
FR2660657B1 (fr) * 1990-04-09 1993-05-07 Adir Nouveaux derives du 3-aminochromane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5273994A (en) * 1990-04-09 1993-12-28 Adir Et Compagnie 3-aminochroman compounds
US5254578A (en) * 1990-10-24 1993-10-19 Sankyo Company, Limited Benzopyran derivatives having anti-hypertensive and vasodilatory activity and their therapeutic use
DE4115521A1 (de) * 1991-05-11 1992-11-12 Beiersdorf Ag Isoindolyl- und isochinolylsubstituierte benzopyran-derivate, zwischenprodukte, sowie verfahren zu ihrer herstellung
US5225566A (en) * 1992-05-08 1993-07-06 American Home Products Corporation Indazolanonyl derivative of benzopyran
US5179118A (en) * 1992-05-08 1993-01-12 American Home Products Corporation Indazolanonyl derivatives of benzopyrans
US5500442A (en) * 1994-06-10 1996-03-19 American Home Products Corporation Cyclobut-3-ene-1,2-dione derivatives as smooth muscle relaxants
US6339093B1 (en) * 1999-10-08 2002-01-15 Hoffmann-La Roche Inc. Isoquinoline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
EP0093535B1 (en) * 1982-04-28 1986-12-30 Beecham Group Plc Novel chromenes and chromans

Also Published As

Publication number Publication date
EP0158923A3 (en) 1989-01-18
DE3584639D1 (de) 1991-12-19
JPS60231674A (ja) 1985-11-18
EP0158923B1 (en) 1991-11-13
GB8409745D0 (en) 1984-05-23
EP0158923A2 (en) 1985-10-23
US4616021A (en) 1986-10-07

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