JPH0558407B2 - - Google Patents

Description

[Detailed description of the invention]

[Industrial Application Field] The present invention provides a novel weakly acidic bath additive, more specifically,
By stably blending crude drug extracts into bath additives that contain carbonates and acids, and which have a slightly acidic bath water PH when used, a mild bath additive that synergistically enhances the blood circulation promoting effect and the moisturizing feeling of the skin. Regarding acidic bath additives. [Prior Art] It is known that bath additives that contain carbonate and acid and have a slightly acidic PH of the bath water exhibit excellent blood circulation promoting effects because the carbon dioxide gas generated remains in the solution. . In order to enhance the bathing effect, the present inventors have developed a weakly acidic bath additive containing herbal medicine (Japanese Patent Application No. 73507/1982). [Problems to be solved by the invention] However, when putting into practical use a weakly acidic bath additive containing this crude drug in the form of tablets, (1) If the crude drug is blended as is, insoluble substances derived from the crude drug may be mixed into the bath water. (2) When extracts of herbal medicines are used, the extracts are placed in the harsh conditions of a mixture of acid and alkali in the tablets, so the active ingredients of the herbal medicines are removed by the time of use. However, there were drawbacks such as decomposition, resulting in decreased effectiveness, and the generation of strange odors. [Means for Solving the Problems] Therefore, the present inventors conducted intensive research in order to eliminate such drawbacks, and as a result, they made oil-absorbing agents that absorbed or adsorbed crude drug extracts into granules or tablets. The present invention was completed based on the discovery that all of these drawbacks can be overcome by using the following as a core. That is, the present invention is characterized in that an oil-absorbing agent that has absorbed or adsorbed a herbal medicine extract is made into granules or tablets, and the granules or tablets are mixed into a foaming component containing a carbonate and an acid to form a tablet. It provides acidic bath salts. Examples of carbonates to be added to the weakly acidic bath additives of the present invention include sodium hydrogen carbonate, sodium carbonate, sodium sesquicarbonate, potassium hydrogen carbonate,
Potassium carbonate, potassium sesquicarbonate, ammonium bicarbonate salt, ammonium carbonate salt, ammonium sesquicarbonate salt, etc. are mentioned, and these can be used alone or in combination of two or more kinds. Further, as the acid, both organic acids and inorganic acids can be used, but water-soluble and solid acids are preferred.
Examples of organic acids include straight chain fatty acids such as formic acid, acetic acid, propionic acid, butyric acid, and valeric acid; oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, fumaric acid, maleic acid, phthalic acid, Dicarboxylic acids such as isophthalic acid and terephthalic acid; acidic amino acids such as glutamic acid and aspartic acid;
Glycolic acid, lactic acid, hydroxyacrylic acid, α
-oxybutyric acid, glyceric acid, tartronic acid, malic acid, tartaric acid, citric acid, salicylic acid (o,
m, p), oxyacids such as gallic acid, mandelic acid, tropic acid, ascorbic acid, gluconic acid; cinnamic acid, benzoic acid, phenylacetic acid, nicotinic acid, kainic acid, sorbic acid, pyrrolidonecarboxylic acid, trimellitic acid, benzene Examples include sulfonic acid, toluenesulfonic acid, and acid salts of these organic acids. Examples of inorganic acids include phosphoric acid, potassium dihydrogen phosphate, sodium dihydrogen phosphate, sodium sulfite, potassium sulfite, sodium pyrosulfite (sodium metabisulfite), potassium pyrosulfite (potassium metabisulfite), and acidic hexamethaline. Examples include sodium acid, potassium acid hexametaphosphate, sodium acid pyrophosphate, potassium acid pyrophosphate, and sulfamic acid. Among these, aliphatic dicarboxylic acids such as succinic acid and adipic acid, fumaric acid, phosphoric acid, and acid salts thereof are preferred. Herbal medicine extracts are not particularly limited, but include, for example, Soujiyutsu, Biyakujiyutsu, Valerian, Keigai, Kobokou, Senkiyu, Spruce, Equilibrium, Aspergillus japonica, Syakuyaku, Aspergillus japonica, Aspergillus scutellariae,
Sanshishi, Keihi, Carrot, Bukuriyo, Tokugaku, Shobu, Gaiyo, Matsubusa, Byakushi, Jiyuyaku, Uikiyo, Chimpi, Campi,
Examples include extracts from herbal medicines such as chamomile. These crude drugs can be used alone or as a mixture of two or more. These herbal medicine extracts include the above herbal medicines in water;
Lower alcohols such as ethanol and isopropanol; Vegetable oils such as soybean oil, sesame oil, and olive oil; Animal oils such as cod liver oil, mink oil, and whale oil; Minerals such as liquid paraffin and petrolatum; Ester oils such as isopropyl myristate and decyl oleate;
Examples include extracts obtained by a method of extraction with a solvent such as a polyhydric alcohol compound or a mixed solvent of two or more thereof, or a method of extraction with a gas such as carbon dioxide gas. Among these, those extracted with water or water/alcohol are particularly preferred. In addition, the oil-absorbing agent may be one that has the ability to absorb, adsorb, and stably retain the oil component of the herbal medicine extract, such as natural products such as starch, dextrin, and cyclodextrin; silica, and calcium silicate. silicates such as clay minerals, pearlite, carbon black, polyurethane polymers, polyolefin polymers, etc. These oil absorbers have an oil retention capacity of 1.5ml/g or more,
Particularly preferred is 3 ml/g or more. The amount of the oil-absorbing agent used varies depending on its type, but is preferably 50 to 500% by weight of the herbal medicine extract (hereinafter simply expressed as %). In order to keep the herbal medicine extracts in the weakly acidic bath additives of the present invention sufficiently stable, the oil-absorbing agent that has absorbed or adsorbed the herbal medicine extracts is made into granules or tablets (particularly tablets are preferred), and the oil absorbent is made into granules or tablets. Therefore, it is necessary to prepare a weakly acidic bath salt in the form of a dry-coated tablet, which is mixed into an effervescent component consisting of a carbonate and an acid and then compressed into a tablet. For the formation of this core, it is generally preferable to use commonly used excipients such as saccharides such as sorbitate and mannite; water-soluble polymers such as sodium polyacrylate and carboxymethyl cellulose. The amount of this excipient is preferably 20-500% of the crude drug extract. Further effects can be obtained by coating these granule or tablet cores with a water-soluble polymeric substance. As the water-soluble polymeric substance, water-soluble coating agents such as hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), and polyethylene glycol (PEG) are preferred. The amount of carbonate and acid in the weakly acidic bath additive of the present invention is as follows:
When bath additives are added to bath water, the ratio is such that the bath water becomes slightly acidic, that is, the PH of a 0.01% aqueous solution of bath additives is
It is necessary to adjust the pH to 4 to 7, particularly preferably 6.0 to 6.7. If the pH is lower than 4, there is a risk of strong skin irritation and damage to the bathtub, etc. If the pH is higher than 7, the effects of the present invention will not be achieved. The effect of the present invention is that when the pH is acidic, carbon dioxide gas exists as CO ₂ molecules and exhibits a blood flow promoting effect, but when the pH is alkaline, carbon dioxide gas exists as CO ^2-3 ions or HCO ^- ₃ ions _. This is based on the principle that the effect is not observed at all because the The blending amounts of carbonate and acid to meet these conditions vary depending on their type, but carbonate should be 5 to 80%, particularly 10 to 50%, and acid should be 10 to 50% of the total composition.
80%, especially 15-50% is preferred. In addition, crude drug extracts can be added in a wide range of amounts, but 0.01 to 20%, especially 0.1 to 10% of the total composition.
is preferred. Furthermore, the bath salts of the present invention may contain commonly-used fragrances, pigments, vitamins, hot spring active ingredients, enzymes, seaweed extracts, lanolin, silicone, etc. in the core or outer shell. can. Further, excipients, binders, disintegrants, lubricants, etc. may be added as necessary for formulation. [Operation and Effects of the Invention] As mentioned above, the weakly acidic bath additive of the present invention has a favorable effect on the skin since its pH is approximately the same as that of human skin. Moreover, the carbon dioxide gas generated when pouring into bath water exists as ions in alkaline conditions and has no effect of promoting blood flow, but in acidic conditions as in the present invention, it exists as CO ₂ molecules and has an excellent effect of promoting blood circulation in the skin. play. Furthermore, the synergistic effect with the stably blended herbal medicine extract without emitting any off-odor due to the decomposition of the herbal medicine ingredients provides excellent bathing effects such as promotion of blood circulation, heat retention, and a moisturizing feeling on the skin. [Example] Next, the present invention will be explained in detail with reference to Examples. Example 1 Powdered mixture of 20% Senkiyu extract and 75% dextrin, 3.5% Glauber's salt, 1.5% Avicel
Mix and tablet to obtain 5 g tablets (core portion). With this tablet as the core, the outer shell components are 30% sodium bicarbonate, 15% sodium carbonate, and 40% succinic acid.
%, 15% Glauber's Salt, and a trace amount of pigment were compressed into tablets each weighing 50 g. This was packaged in an aluminum film and made into a product. Example 2 A bath salt weighing 50 g per tablet was produced in the same manner as in Example 1, except that the extract was replaced with the Angelica extract. Example 3 A bath salt weighing 50 g per tablet was produced in the same manner as in Example 1, except that the extract was replaced with the extract of the chinpiper. Comparative Example 1 In Example 1, a bath salt of 50 g per tablet was produced by simply mixing and tableting the core part and the outer shell part without making small tablets. Comparative Example 2 In Example 2, a bath additive of 50 g per tablet was produced by simply mixing and tableting the core portion and the outer shell portion without making small tablets. Comparative Example 3 In Example 3, a bath salt of 50 g per tablet was produced by simply mixing and tableting the core part with the outer shell part without making small tablets. Example 4 The effect of the bath additive of the present invention on blood flow and skin surface temperature was investigated as follows. <Method> Eight subjects were allowed to take a bath for 10 minutes in a hot bath, a bath with added bath additives in Comparative Example 1, or a bath with added bath agents in Example 1 according to the present invention, and various measurements were taken before and after taking the bath. The water temperature was 40°C and the room temperature was 25°C, and the bath additives were diluted to a 0.02% solution. For measurement, a laser Doppler blood flow meter was used for the blood flow meter, and an infrared thermometer was used for the skin surface temperature. <Results> The measurement results are shown in Table 1 (blood flow) and Table 2 (skin surface temperature). In addition, the numerical value was shown as the average value of 8 people. As is clear from Tables 1 and 2, it can be seen that the products of the present invention exhibit excellent blood circulation promoting effects and heat retention effects.

[Table] Shows relative values when

[Table] Example 5 The bath additives of Examples 1 to 3 and Comparative Examples 1 to 3 were prepared, each bath additive was added to bath water to make a 0.03% solution, and 10 panelists were given a standard method for one month. The bath additives were used according to the instructions, and the overall evaluation (overall feeling of use) as a bath additive, the feeling of warmth, whether or not the water cooled, and the feeling of moisturizing the skin were evaluated. The results are shown in Table 3. It can be seen that the examples are excellent in all cases.

【table】

Claims (1)

[Claims] 1. A weakly acidic bath additive characterized by granulating or tableting an oil-absorbing agent that has absorbed or adsorbed crude drug extracts, and mixing the granules or tablets as a core into a foaming component containing carbonate and acid to form a tablet.