JPH0334919A - Bathing agent - Google Patents
Bathing agentInfo
- Publication number
- JPH0334919A JPH0334919A JP17028789A JP17028789A JPH0334919A JP H0334919 A JPH0334919 A JP H0334919A JP 17028789 A JP17028789 A JP 17028789A JP 17028789 A JP17028789 A JP 17028789A JP H0334919 A JPH0334919 A JP H0334919A
- Authority
- JP
- Japan
- Prior art keywords
- bath
- salt
- hyaluronic acid
- bathing agent
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000003287 bathing Methods 0.000 title abstract description 11
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 14
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 14
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000013040 bath agent Substances 0.000 claims description 9
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims description 8
- 229940014041 hyaluronate Drugs 0.000 claims description 8
- 150000003839 salts Chemical class 0.000 abstract description 17
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract description 9
- 239000004094 surface-active agent Substances 0.000 abstract description 8
- 102000004190 Enzymes Human genes 0.000 abstract description 6
- 108090000790 Enzymes Proteins 0.000 abstract description 6
- -1 antiseptic Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 239000000203 mixture Substances 0.000 abstract description 6
- 239000003795 chemical substances by application Substances 0.000 abstract description 5
- 239000000843 powder Substances 0.000 abstract description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract description 4
- 229930003231 vitamin Natural products 0.000 abstract description 4
- 239000011782 vitamin Substances 0.000 abstract description 4
- 235000013343 vitamin Nutrition 0.000 abstract description 4
- 229940088594 vitamin Drugs 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract description 3
- 150000001720 carbohydrates Chemical class 0.000 abstract description 3
- 239000003086 colorant Substances 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 abstract description 3
- 239000013078 crystal Substances 0.000 abstract description 2
- 239000000499 gel Substances 0.000 abstract description 2
- 239000008187 granular material Substances 0.000 abstract description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract description 2
- 239000003826 tablet Substances 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 239000003788 bath preparation Substances 0.000 description 16
- 239000000654 additive Substances 0.000 description 15
- 230000003020 moisturizing effect Effects 0.000 description 15
- 230000000996 additive effect Effects 0.000 description 7
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 6
- 150000002334 glycols Chemical class 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 4
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 3
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000001569 carbon dioxide Substances 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000012459 cleaning agent Substances 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- OWGIPADQEWDBDL-UHFFFAOYSA-N hyalic acid Natural products C1CC2(OC(=O)C3=C)CC3CCC2C2(C)C1C(C)(C(O)=O)CCC2 OWGIPADQEWDBDL-UHFFFAOYSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229940041616 menthol Drugs 0.000 description 3
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 description 3
- 235000011152 sodium sulphate Nutrition 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- 150000008163 sugars Chemical class 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 239000001630 malic acid Substances 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 2
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 2
- 229960003415 propylparaben Drugs 0.000 description 2
- BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- BKMMTJMQCTUHRP-UHFFFAOYSA-N 2-aminopropan-1-ol Chemical class CC(N)CO BKMMTJMQCTUHRP-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000092897 Angelica japonica Species 0.000 description 1
- 241000218691 Cupressaceae Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010073150 Multiple endocrine neoplasia Type 1 Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- PXJJSXABGXMUSU-UHFFFAOYSA-N disulfur dichloride Chemical compound ClSSCl PXJJSXABGXMUSU-UHFFFAOYSA-N 0.000 description 1
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 159000000011 group IA salts Chemical class 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002366 lipolytic effect Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035485 pulse pressure Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Abstract
Description
【発明の詳細な説明】
[産業上の利用分野]
本発明は、浴用剤に関し、潔上り後の肌に対して充分な
保湿効果が得られる浴用剤に関するものである。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a bath additive, and more particularly, to a bath additive that provides a sufficient moisturizing effect on the skin after cleansing.
「従来の技術]
従来から、入浴の効果をに<りるため凪呂、浴場等に浴
用剤が用いられてきた。浴用剤は、一般に無機塩類混合
物に、香料、色素、ビタミン類、酵素、植物エキス、有
機酸塩等を配合したもので、浴場に香りや色調を与えた
り、皮膚表面に適度の刺激を与えることにより、血液の
循環を活発にし、疲労回復、新陳代謝を増進させるもの
である。``Prior Art'' Traditionally, bath additives have been used in calm baths, bathhouses, etc. to enhance the effects of bathing.Bath additives generally contain a mixture of inorganic salts, fragrances, pigments, vitamins, enzymes, Contains plant extracts, organic acid salts, etc., and adds scent and color to the bath, and by providing moderate stimulation to the skin surface, activates blood circulation, recovers from fatigue, and improves metabolism. .
これら浴用剤の中で、アルカリ塩類と酸類との配合によ
り、炭酸ガスを発生せしめるものは、血行を促進し、湯
上りの後の保熱(保温)効果を有している(特開昭62
−45515号公報。)。Among these bath additives, those that generate carbon dioxide gas by blending alkaline salts and acids promote blood circulation and have a heat retention effect after bathing (Japanese Patent Laid-Open No. 62
-45515 publication. ).
[発明が解決しようとづ−る課題]
しかしながら、従来の浴用剤は保湿効果がf分とはいえ
ず、そのため、潟上り後の肌にうるおいを与えることに
対して十分に満足できるものではなかった。[Problem to be solved by the invention] However, the moisturizing effect of conventional bath additives cannot be said to be as high as F, and therefore, they are not fully satisfactory in providing moisture to the skin after bathing. Ta.
本発明は、上記の問題点を解決するためになされたもの
であり、本発明の目的は、湯上り後の肌に充分うるおい
を与えることのできる浴用剤即ち顕著な保湿効果を有す
る浴用剤を提供することである。The present invention has been made to solve the above problems, and an object of the present invention is to provide a bath agent that can sufficiently moisturize the skin after taking a bath, that is, a bath agent that has a remarkable moisturizing effect. It is to be.
[課題を解決するための手段]
本発明は、上記目的を達成するためになされたものであ
り、浴槽中の温水に溶かし込んで用いる、主成分がヒア
ルロン酸及び/又警よヒアルロン酸塩であることを特徴
とする浴用剤である。[Means for Solving the Problems] The present invention has been made to achieve the above object, and the present invention is made by dissolving in hot water in a bathtub and using it as a main component consisting of hyaluronic acid and/or hyaluronate. It is a bath additive characterized by the following.
本発明の浴用剤に使用されるヒアルロン酸及び/又はヒ
アルロン酸塩は、分子量が1万〜1000万、好ましく
は、10万〜800万のもので・ある11分子量が1万
未満のものでは、保湿効果が不足し、1000万より大
きいもの−Cは、べたつさ感等の皮膚異和感を発生させ
、好ましくない。The hyaluronic acid and/or hyaluronate used in the bath preparation of the present invention has a molecular weight of 10,000 to 10 million, preferably 100,000 to 8 million.11 If the molecular weight is less than 10,000, -C, which lacks moisturizing effect and has a molecular weight of more than 10 million, is undesirable because it causes discomfort on the skin such as stickiness.
般にヒアル1]ン酸に(よ、例えば、鶏の1〜ザカ、脈
圧、動物すしくは魚類の眼球硝子体等の天然物より抽出
されたもの、微生物を利用して生産されたもの、合成的
手法により得られたもの等があるが、本発明の浴用剤に
は、いかなる製造法によって得られたもの(必要に応じ
て精製したもの)も使用可能である。In general, hyalic acid (for example, those extracted from natural products such as chicken, pulse pressure, animal or fish ocular vitreous, and those produced using microorganisms) , those obtained by synthetic methods, etc., but those obtained by any manufacturing method (purified if necessary) can be used in the bath agent of the present invention.
本発明にお(づるヒアルロン酸の塩としでは、例えば、
ブ1〜リウム塩、カリウム塩智のアルノJり金属塩、マ
グネシウム塩、カルシウム塩等のアルカリ土類金屈j2
.+:、アン−[ニウム塩、l−り王りノールアミン地
、β−プロパノールアミン塩等のアルカノールアミン1
2□1、リジン塩、アル−1゛ニン塩、ヒスデシン塩等
の塩基性アミンR塩等が用いられるが、これらに限定さ
れるものではなく、いかなるちのも使用可能である。ヒ
アルロン酸塩の方が一般にヒアル[]ン酸白休よりら保
温中」が人きく実用に適しており、特に、ヒアル[1ン
酸のす1〜リウム塩であるヒアル1]ン酸す1〜リウム
が奸ましい。In the present invention, for example, as a salt of hyaluronic acid,
Alkaline earth metal salts such as metal salts, magnesium salts, calcium salts, etc.
.. +: Alkanolamine 1 such as an-[nium salt, l-trianolamine salt, β-propanolamine salt, etc.
Basic amine R salts such as 2□1, lysine salt, al-1'ine salt, and hisdecine salt are used, but the present invention is not limited to these, and any salt can be used. Hyaluronate is generally more suitable for practical use than hyaluronic acid because it retains heat, and is especially suitable for practical use. ~Rium is disgusting.
本発明の浴用剤に使用されるヒアルロン酸及び/又はヒ
アルロン酸塩のlYt i;L、その浴用剤を浴槽中の
温水に溶かし込んだ時、ヒアルロン酸及び/又はヒアル
ロン酸塩のi11度(入浴+1& 濃度)が、0゜00
01〜b、 OW/V%、好まL<は0.001〜0.
1 W/V%となるJ:うな串がよい。090001
W/V%未満の濃度では、充分な保湿効果が1ミノられ
ず、濃度が5.0W/V%を超えても保湿効果の顕著な
上昇は認められない。lYt i;L of the hyaluronic acid and/or hyaluronate used in the bath preparation of the present invention, when the bath preparation is dissolved in warm water in a bathtub, the i11 degree of hyaluronic acid and/or hyaluronate +1 & concentration) is 0°00
01-b, OW/V%, preferably L< is 0.001-0.
1 W/V% J: Eel skewers are good. 090001
If the concentration is less than W/V%, no sufficient moisturizing effect will be achieved, and even if the concentration exceeds 5.0 W/V%, no significant increase in the moisturizing effect will be observed.
本発明は、その保湿効果を一層高めるために、グリコー
ル類、糖類等を添力nすることができる。In the present invention, glycols, saccharides, etc. can be added in order to further enhance the moisturizing effect.
グリコール類として(よ、例えば、プ「]ピレングリコ
ール、1.3−ブヂレングリ]−ル、ポリエチレングリ
コール碧が用いられる。糖類としては、例えば、ソルビ
1〜−ル、マンニ(〜−ル、キノリ1〜ル等が用いられ
る。グリコール類及び糖類は、それら自体保湿作用を石
するしのであるが、ヒアルロン酸及びヒアル1]ン酸j
詠(以下、ヒアル[1ン酸(塩)という)の有1−る保
湿力と相乗的に作用して、本発明の浴用剤の保湿効果を
一段ど向りさぜることができる。また、グリコール類又
は糖類を本発明の浴用剤に添加づ゛ることにJ:す、本
発明の浴用剤の保湿効果を紺持しながら、ヒアルロン酸
(塩)の配合行1を減らずことができるため、製造原価
(原料111j価)を低減りることかrIJ能となり、
製造上の利点【ま大きい。グリコール類及び糖類の前述
した効果を奏するには、入浴時S度0.02−・207
9%が適当でおる1、
更に、本発明の浴用剤には、必要に応じ−(、界面活性
剤、温泉の有効成分、ビタミン紅1、生薬、酵素、μj
腐剤、着色剤等を適宜添加づることがでさる。Examples of glycols used include pyrene glycol, 1,3-butylene glycol, and polyethylene glycol. Examples of sugars include sorbyl, manni, and quinol. Glycols and sugars themselves have a moisturizing effect, but hyaluronic acid and hyaluronic acid
By acting synergistically with the moisturizing power of hyalic acid (hereinafter referred to as hyalic acid (salt)), the moisturizing effect of the bath preparation of the present invention can be further improved. Furthermore, by adding glycols or sugars to the bath preparation of the present invention, it is possible to maintain the moisturizing effect of the bath preparation of the present invention without reducing the content of hyaluronic acid (salt). This reduces manufacturing costs (raw material 111j value) and improves IJ performance.
Manufacturing advantages [major. In order to achieve the above-mentioned effects of glycols and saccharides, the degree of S during bathing must be 0.02-207.
9% is appropriate1.Furthermore, the bath preparation of the present invention may contain - (surfactants, active ingredients of hot springs, vitamin red 1, herbal medicines, enzymes, μj
Preservatives, coloring agents, etc. can be added as appropriate.
界面活+1剤は、他の配合成分の溶解補助剤として作用
力る。さらに、本発明に浴用剤とtま別の用途である洗
浄剤としての作用を付与し、本発明を浴槽中の温水を泡
)1−だせて使用づ−る「バス・フ第ム1と呼ばれる浴
用洗浄剤どづる場合、界面活性剤を積極的に配合づるこ
とができる。本発明の浴用剤に用いられる界面活性剤と
しては特に限定はされないが、非イオン系界面活性剤が
適当であり、分子量1,000〜20,000の高分子
界面活性剤、例えばポリオキシエチレンボリオギシプロ
ピレンブロックコボリマー等が挙げられる。The surfactant +1 agent acts as a solubilizing agent for other ingredients. Furthermore, the present invention has been imparted with the function of a cleaning agent, which is different from a bath agent, and the present invention has been applied to a bath bath product 1, which is used to generate bubbles from hot water in a bathtub. In the case of a so-called bath cleaning agent, a surfactant can be actively added.The surfactant used in the bath cleaning agent of the present invention is not particularly limited, but nonionic surfactants are suitable. , polymeric surfactants having a molecular weight of 1,000 to 20,000, such as polyoxyethylene boriopropylene block copolymer.
本発明の浴用剤に用いられる温泉の有効成分としては、
例えば、硫酸ナトリウム(芒硝泉)、炭酸水素す1〜リ
ウム(重曹泉)、炭酸ナトリウム(炭酸泉)、塩化す1
〜リウム(食塩泉)等が用いられ、各々特有の温泉効果
を奏する。The active ingredients of hot springs used in the bath preparation of the present invention include:
For example, sodium sulfate (sodium salt spring), sodium hydrogen carbonate (sodium bicarbonate spring), sodium carbonate (carbonated spring), sulfur chloride
-Rium (salt spring) etc. are used, and each has its own unique hot spring effect.
ビタミン類としては、ビタミンC類、ビタミンB類等が
用いられる。As the vitamins, vitamin C, vitamin B, etc. are used.
生薬としては、トウキ、センキュウ、チンピ、コウボク
等が用いられる。As herbal medicines, Angelica japonica, Senkyu, Chinpi, Koboku, etc. are used.
酵素としては、蛍白分解酵素、脂質分解酵素等が用いら
れる。As the enzyme, a fluorolytic enzyme, a lipolytic enzyme, etc. are used.
防腐剤どしては、メブルパラベン、プロピルパラベン等
のパラベン類、ソルビン酸カリウム等が用いられる1、
着色剤どしては、緑e 204号、黄色4÷う、フルオ
レ上インナ1ヘリウム等が用い1うれる。As preservatives, parabens such as mebluparaben and propylparaben, potassium sorbate, etc. are used.As for coloring agents, Green E No. 204, Yellow No. 4 ÷ U, Fluorine Inner 1 Helium, etc. are used. 1 I'm happy.
本発明の浴用剤には、1i7i述したもの以外に、無機
塩類、有機塩類、右#M酸等を添加してもよい。In addition to those mentioned above, inorganic salts, organic salts, #M acids, etc. may be added to the bath agent of the present invention.
また、本発明には、油臭成分どしで、メン1ヘル、ゲル
コール酸、リンゴ酸貴を添加づることができる。なお、
メン1〜−ルを本発明の浴用剤に添加した場合、清涼感
を右号る浴用剤を19ることかできる。1
また、浴用剤の形態は、粉末、顆粒、結晶、錠剤、液体
、ゲル等いかなる形状にもでき、これらの製品化のた必
に必要に応じて賦形剤、結合剤、崩壊剤、滑沢剤、安定
化剤等を添加づることができる。In addition, in the present invention, among the oily odor components, menlic acid, gelcholic acid, and malic acid can be added. In addition,
When men 1 to 1 are added to the bath preparation of the present invention, a bath preparation with a refreshing feeling can be obtained. 1 Bath additives can be in any form such as powder, granules, crystals, tablets, liquids, and gels, and excipients, binders, disintegrants, and lubricants may be added as necessary to produce these products. A thickening agent, a stabilizer, etc. can be added.
「実施例]
以下、本発明を実施例により訂細に説明するが、本発明
はこれらによって伺ら限定されるものではない、。"Examples" The present invention will be explained in detail below using Examples, but the present invention is not limited by these Examples.
「実施例1〜実施例5]
分子星がそれぞれ、2万、15万、80万、200万、
及び700万のピノフル1]ン酸ナトリウム5師類、訪
腐剤であるメブルパラベン、プロピルパラベン及び香料
を一定徂の温水に溶解2ぎせて、表1の濃度と4たるよ
うに実施例1〜実施例5の各実施例の浴用剤を調製した
5゜
上記の各実施例についで、ト記方法により評価し Iこ
。"Example 1 to Example 5" The number of molecular stars is 20,000, 150,000, 800,000, 2,000,000, respectively.
and 7 million sodium pinoflu 1] phosphate, preservatives mebluparaben, propylparaben, and fragrance were dissolved in warm water of a certain range, and the concentrations were as shown in Table 1. The bath additives of each example in Example 5 were prepared and evaluated using the method described in (G) for each of the above examples.
評価方法:
実施例1〜実施例5において、ヒアルロン酸すI−リウ
ムを添加せず、他の成分はそのまま実施例の配合量で調
製し、比較例1〜比較例5とした。Evaluation method: In Examples 1 to 5, I-lium hyaluronate was not added, and the other components were prepared in the same amounts as in the examples to give Comparative Examples 1 to 5.
実施例1〜5及び比較例1へ・5の各浴用剤を浴檜に注
入し、無作意に抽出したパネラ−20名(男女各10名
)に、常法に従い入浴してもらい、潟上り後の肌のうる
おい(Jlllのしっとり感〉に関する感想を調べた。Examples 1 to 5 and Comparative Example 1 Each of the bath additives in Example 1 and 5 was injected into a bathing cypress tree, and 20 randomly selected panelists (10 men and women each) were asked to take a bath in the usual manner. We looked into impressions regarding the moisture of the skin after climbing (Jllll's moist feeling).
表
その結果、実施例1〜5の各実施例は比較例1〜5ど比
較して充分な保湿効果を右づ゛るとの感想を得た。As a result, it was felt that each of Examples 1 to 5 had a more sufficient moisturizing effect than Comparative Examples 1 to 5.
[実施例6] 本例の浴用剤は液剤である。[Example 6] The bath preparation of this example is a liquid preparation.
ヒアルロン酸す1−リウム
E分子fR200万] (0,7%) 57’
Rh’i%塩化す1〜リウム 19重
徂%プロピレングリコール 18@邑%立−
メントール 5重量%ポリオキシエ
ヂレンポリオキシプロピレンブロックコボリマ−(界面
活性剤) 1@吊%上記の組成を有する浴用剤は、下記
の方法により調製した。Hyaluronate monolithium E molecule fR2 million] (0.7%) 57'
Rh'i% Sourium chloride 19% Propylene glycol 18% Sourium chloride
Menthol 5% by weight Polyoxyethylene polyoxypropylene block cobolimer (surfactant) 1% by weight A bath agent having the above composition was prepared by the following method.
とアルロン酸ナトリウムは、撹拌しながら水に溶解し、
0.7%溶液どする。これに塩化ブトリウム、界面活性
剤を加え、ざらにプロピレングリコールにて溶解したl
−メント−ルを加え、沈澱物が残らぬように撹拌づ−る
。and sodium aluronate are dissolved in water with stirring,
Dispense the 0.7% solution. Add butrium chloride and a surfactant to this, and dissolve it in propylene glycol.
- Add menthol and stir until no precipitate remains.
本浴用剤の標準使用量は、湧1見に対し1gで 0 ある。The standard usage amount of this bath agent is 1 g for 1 spring. be.
[実施例7] 本例の浴用剤は錠剤である。[Example 7] The bath preparation in this example is a tablet.
ヒアルロン酸ナトリウム
[分子量200万] (粉末) 0.4重に1%炭酸
水素カリウム /1Ofi吊%クエン酸
20重損気炭酸ナトリウム
8重量%四ホウ酸す1〜リウム
8型組%ポリオキシエチレンポリオキシ
プロピレンブロックコボリマ−1重量%
硫酸ナトリウム 22.6重暢%上記の組
成で得られた浴用剤は1錠当り50yの錠剤に成形し、
防湿シーhにで包装した。Sodium hyaluronate [molecular weight 2,000,000] (powder) 0.4 parts by weight 1% potassium bicarbonate / 1% by weight citric acid 20 parts by weight sodium carbonate 8 parts by weight 1-lithium tetraborate
8% polyoxyethylene polyoxypropylene block cobolimer - 1% by weight Sodium sulfate 22.6% by weight The bath preparation obtained with the above composition was molded into tablets of 50y each.
It was wrapped in a moisture-proof sheet.
本例の浴用剤は、1001にターし1錠の使用が標準で
ある。The standard use of the bath preparation in this example is one tablet per 1001.
[実施例8] 本例の浴用剤は粉末である。[Example 8] The bath additive in this example is a powder.
ヒアルロン酸ノー1〜リウム
[分子量200万1 (粉末) 0.4重邑%1
塩化す]・リウム 40重量%リンゴ
酸 20重型組炭酸ナトリウム
10重量%ポリオキシエヂレンボリ
オギシプロピレンブロックコボリマ−1重量%
硫酸ナトリウム 28.6重量%上記の組
成で得られた浴用剤は、1丈に対し0゜59の使用が標
準である。本例の浴用剤は、503ずつ防漏シートにて
包装した。Hyaluronic acid No. 1 - Lium [molecular weight 2,000,000 1 (powder) 0.4% chloride] Lium 40% by weight Malic acid 20% by weight Sodium carbonate 10% by weight Polyoxyethylene polyoxypropylene block cobolimer 1% by weight Sodium sulfate 28.6% by weight For bath additives obtained with the above composition, the standard use is 0°59 per length. The bath preparation of this example was packaged in 503 pieces with a leak-proof sheet.
〈実施例6〜8の評価〉
実施例6〜8についても各々の標準使用量に従って溶解
させ、(好ましい使用方法は、各個とも予め浴槽に各浴
用剤を投入しておき、後から渇または水を注入し、その
水流を利用して溶解・混合させる方法である。)前述し
た評価方法により評価した。<Evaluation of Examples 6 to 8> Examples 6 to 8 were also dissolved according to each standard usage amount (the preferred usage method is to put each bath agent in the bathtub in advance, and then add it to the bathtub after thirst or water. (This method involves dissolving and mixing by injecting water and using the water flow.) Evaluation was performed using the evaluation method described above.
各実施例は、いずれも顕著な保湿効果を有していた。ま
た、実施例6では見−メントールが含有されており、入
浴中および入浴後において、冷やかな清涼感が感じられ
た。Each Example had a remarkable moisturizing effect. Furthermore, in Example 6, menthol was contained, and a cool refreshing feeling was felt during and after bathing.
2
ざらに、実施例7の浴用剤では、炭酸ガスを発生ずる発
砲錠どなっており、炭酸ガスが皮膚表面に適度の刺激を
与え、血行を促進することにJ:す、湯上り後の保湿効
果も得られた。2 In general, the bath additive of Example 7 is a foam tablet that generates carbon dioxide gas, and the carbon dioxide gas moderately stimulates the skin surface and promotes blood circulation. It was also effective.
[発明の効果1
以上詳述したように、本発明の浴用剤によれば、湯上り
後の肌にしっとりしたうるおいを与えることができ、充
分な保湿効果が得られる。従って、本発明の浴用剤は極
めて有用な浴用剤である。[Effect of the Invention 1] As detailed above, the bath preparation of the present invention can provide moisturizing to the skin after taking a bath, and can provide a sufficient moisturizing effect. Therefore, the bath additive of the present invention is an extremely useful bath additive.
Claims (1)
ン酸及び/又はヒアルロン酸塩であることを特徴とする
浴用剤。A bath agent characterized in that its main component is hyaluronic acid and/or hyaluronate, which is used by dissolving it in hot water in a bathtub.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17028789A JPH0334919A (en) | 1989-06-30 | 1989-06-30 | Bathing agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17028789A JPH0334919A (en) | 1989-06-30 | 1989-06-30 | Bathing agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH0334919A true JPH0334919A (en) | 1991-02-14 |
Family
ID=15902155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17028789A Pending JPH0334919A (en) | 1989-06-30 | 1989-06-30 | Bathing agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0334919A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR1001424B (en) * | 1993-02-04 | 1993-11-30 | Spyros Tsakas | Cosmetic products in the form of effervescent or non-effervescent tablets |
JPH06321714A (en) * | 1993-05-10 | 1994-11-22 | Taki Chem Co Ltd | Preservative or medicated bath |
JP2016199516A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Gel-like cosmetic |
JP2016199518A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Skin improving agent |
JP2016199515A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Emulsion cosmetic |
-
1989
- 1989-06-30 JP JP17028789A patent/JPH0334919A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR1001424B (en) * | 1993-02-04 | 1993-11-30 | Spyros Tsakas | Cosmetic products in the form of effervescent or non-effervescent tablets |
JPH06321714A (en) * | 1993-05-10 | 1994-11-22 | Taki Chem Co Ltd | Preservative or medicated bath |
JP2016199516A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Gel-like cosmetic |
JP2016199518A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Skin improving agent |
JP2016199515A (en) * | 2015-04-13 | 2016-12-01 | キユーピー株式会社 | Emulsion cosmetic |
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