JPH04364119A - Bathing agent composition - Google Patents

Abstract

PURPOSE:To provide a bathing agent composition containing an alkaline inorganic salt and a proteinase, exhibiting slightly alkaline nature and excellent cleaning effect in dissolution, giving smoothing and refreshing feeling to the skin after bath and effective for the treatment of heat rashes, pimples, etc. CONSTITUTION:The objective bathing agent composition contains (A) an alkaline inorganic salt such as sodium carbonate, borax, sodium metasilicate and sodium sulfate (especially preferably sodium carbonate) and (B) a proteinase such as pancreatin obtained from the pancreas of pig or cattle (especially preferably a proteinase originated from microorganism of the genus Bacillus) and exhibits pH 8.0-10.0 when dissolved in bath water. The concentration of the alkaline inorganic salt such as sodium carbonate is adjusted to 20-200ppm, preferably 30-150ppm and the content of the proteinase is preferably selected to >=0.1wt.%.

Description

[Detailed description of the invention]

0001

[Industrial Application Field] The present invention has an excellent skin cleansing effect, makes the skin smooth and refreshed after bathing, and has a remarkable improvement effect on skin diseases such as heat rash and acne. The present invention relates to bath agent compositions.

0002

[Prior Art] Various bath agent compositions have been known to be added to bath water, and their composition consists of inorganic salts such as sodium sulfate, sodium chloride, and sodium hydrogen carbonate, fragrances, and pigments. The main thing is the addition of . These bath agent compositions are intended to promote blood circulation, relieve fatigue, cleanse the skin, and relax the mind and body.

[0003] Skin stains include sebum, grime, sweat, and dust, and skin cleansing with bath additives primarily aims to remove sebum using the alkalinity of sodium bicarbonate.

[0004] However, because the alkalinity of sodium hydrogen carbonate is weak, the pH of the bath water hardly changes at the concentration used in a typical bath agent composition and remains around neutral, making it impossible to obtain a sufficient sebum removal effect. Ta. Furthermore, although there was a slight sebum removal effect, no removal effect on dead skin cells, that is, scale, was observed.

[0005] Therefore, in order to enhance the scale removal effect, a bath agent composition containing a proteolytic enzyme was developed.

[0006] However, proteolytic enzymes generally used in bath agent compositions originally exhibit the highest activity under pH conditions of 8.0 to 10.0; Since bath agent compositions are used with almost neutral bath water, they cannot exhibit the desired effect, and as a result, the current situation is that a sufficient scale removal effect cannot be obtained.

[0007]Furthermore, a bath composition that has a remarkable symptom-improving effect on skin diseases such as heat rash and acne has not yet been developed.

[0008]

[Problems to be Solved] Therefore, the present invention has an excellent skin cleansing effect, provides a smooth and refreshing feeling to the skin after bathing, and also provides noticeable symptoms for skin diseases such as heat rash and acne. The present invention provides a bath agent composition having improved effects.

[0009]

[Means for Solving the Problems] As a result of intensive research in order to solve the above-mentioned problems, the present inventors have developed a method that contains alkaline inorganic salts and proteolytic enzymes, and which has an 8.
A bath additive composition with a pH value of 10.0 to 10.0 has an excellent skin cleansing effect, leaving the skin smooth and refreshed after bathing, and is also effective against skin diseases such as heat rash and acne. The present invention was completed based on the discovery that it has a symptom-improving effect.

[0010] That is, the present invention is a bath composition characterized by containing alkaline inorganic salts and proteolytic enzymes and exhibiting a pH value of 8.0 to 10.0 upon dissolution (hereinafter referred to as the present invention). bath agent composition).

The details of the bath agent composition of the present invention will be explained below.

Specific examples of alkaline inorganic salts in the bath agent composition of the present invention include sodium carbonate, borax, sodium metasilicate, and sodium sulfide. Among these, sodium carbonate is preferred in terms of stability, safety, and alkalinity.

[0013] The amount of inorganic salts that are alkaline when dissolved in water is such that the bath water has a pH of 8.0 to 10.0.
A quantity that is a value is required.

[0014] This is because, if the pH value is less than 8.0 when dissolved in bath water, the sebum removal effect due to alkalinity will not be exerted, and the enzyme activity will not be sufficiently exerted, resulting in the inventive problem. This is because the intended purpose is not fully achieved. Further, if the pH value exceeds 10.0 when dissolved in bath water, the alkalinity is too strong and it has an adverse effect on the skin, which is not preferable. Taking sodium carbonate as an example, although there is some variation depending on the bath water, it is necessary to adjust the concentration of sodium carbonate in the bath water to 20 ppm or more and 200 ppm or less, preferably 30 ppm or more and 150 ppm or less.

[0015] As the protease in the bath agent composition of the present invention, a protease derived from an animal or a microorganism can be used.

[0016] Specific examples of animal-derived proteases include pancreatin obtained from the pancreas of pigs and cows, and specific examples of microbial-derived proteases include pancreatin produced by microorganisms of the genus Bacillus. Bioplase Conc (Nagase Seikagaku Kogyo Co., Ltd.) and the like are mentioned, but from the viewpoint of odor, stability, solubility, etc., proteolytic enzymes derived from microorganisms of the genus Bacillus are preferred.

The content of the proteolytic enzyme is desirably 0.1% by weight or more based on the entire bath agent composition, since if it is less than 0.1% by weight, the scale removal effect will not be sufficient.

Furthermore, the bath agent composition of the present invention has a p
The following components can be added as long as they do not affect the stability of H and protease.

Inorganic salts sodium chloride, potassium nitrate, sodium nitrate, calcium nitrate, aluminum sulfate, sodium sulfate, sodium polyphosphate, ammonium chloride, iron sulfate, sodium phosphate, magnesium sulfate, sodium thiosulfate,
Sodium bicarbonate, sodium sesquicarbonate, sodium sulfide, borax, calcium oxide, magnesium carbonate,
Potassium chloride, potassium bromide, sodium hyposulfite, etc.

[0020] Inorganic acids Boric acid, metasilicic acid, silicic anhydride, etc.

Organic acids such as benzoic acid, citric acid, fumaric acid, tartaric acid, pyrrolidonecarboxylic acid, salicylic acid, succinic acid, malic acid, etc.

[0022] Herbal medicines Sojutsu, Sandalwood, Valerian, Cucumber, Kobokou, Senkyu, Angelica, Ginger powder, Carrot, Keihi, Peony, Mentha leaf, Scutellariae, Sanshishi, Bukuriyo, Helicopter cutlet, Calamus, Samifolia, Alpinia, Juniperina, Juyaku, Saffron, oak extract, chimpi, fennel, can husk, chamomile, melissa, rosemary, horse chestnut, arnica, etc.

Fats and oils Bran oil, rice bran extract, turpentine oil, isopropyl palmitate, isopropyl myristate, squalane, tri(caprylic-capric) glycerin, olive oil,
Soybean oil, liquid paraffin, jojoba oil, white petrolatum, etc.

Pigments Red No. 2, Yellow No. 4, Green No. 3, Blue No. 1, Red 213
No. 1, orange No. 205, green No. 201, blue No. 201, red No. 106, yellow No. 202, green No. 204, etc. Pigments listed in the Ministry of Health and Welfare Ordinance Tar Pigment Appended Table 1 and 2, Chlorophyll,
Natural pigments recognized as food additives such as riboflavin, annatto, canthaxanthin, crocin, cochineal, safflower, and anthraquinone.

Alcohols ethanol, stearyl alcohol, isopropyl alcohol, cetyl alcohol, hexadecyl alcohol, etc.

[0026] Polyhydric alcohols Glycerin, propylene glycol, sorbitol, etc.

Surfactants: sodium laurate, sodium polyoxyethylene lauryl ether sulfate, polyoxyethylene alkyl ether sulfate, lauric acid diethanolamide, polyethylene glycol monostearate, etc.

Fragrances Natural fragrances such as lavender oil, jasmine oil, lemon oil, rose oil, orange oil, pine oil, etc. and synthetic fragrances such as geraniol, citronellol, phenylethyl alcohol, benzyl acetate.

Other ingredients include sulfur, mineral sand, hot water, casein, neutral clay, sodium salicylate, sodium carboxymethyl cellulose, egg yolk powder, sucrose, mica powder, skim milk powder, polyvinylpyrrolidone, and the like.

Furthermore, in addition to the above, the bath agent composition of the present invention may optionally contain sterilizing preservatives (eg, benzoic acid, benzoic acid esters, sorbic acid, etc.), sequestering agents (eg, EDTA, NTA, A wide range of other raw materials such as citric acid, amino acids, and vitamins can be added.

As the mixer, any device can be used as long as it is used for stirring and mixing powders. Specifically, examples thereof include a Bartoh mixer, a Nauta mixer, a universal stirring mixer, a V-shaped mixer, and the like. In addition, the mixing time for the bath agent composition may be as long as it is necessary for the constituent components to be mixed uniformly, and when using the mixer mentioned in the example above, the mixing time is usually 5 to 50 minutes at room temperature. do it.

Next, an experimental example comparing the bath agent composition of the present invention and a conventional bath agent composition will be given. It will be explained that it not only makes the skin smooth and feels refreshed, but also has a remarkable symptom-improving effect on skin diseases such as heat rash and acne.

[0033]

[Experiment example]

■Bath water Examples 1 to 5 having the composition shown in Table 1,
Comparative Examples 1 to 5 bath agent compositions were prepared, and each bath agent composition was dissolved in 42° C. bath water to a concentration of 30 g/200 liters (150 ppm).

Comparative examples were classified into those containing proteolytic enzymes (Comparative Example 1) and those containing no proteolytic enzymes (Comparative Examples 2 to 5) with reference to commercially available bath additives.

Table 1

■Sebum removal effect, scale removal effect, and bathing sensation Ten healthy men and women were asked to take a bath for 5 minutes, and after bathing, the sebum removal effect, scale removal effect, and bathing sensation were evaluated. The results are shown in Table 2. Note that these test methods and evaluation criteria were as follows.

(Sebum removal effect) 5cm of the bather's forearm
Apply 0.1 g of beef tallow evenly on a 5 cm area, extract the remaining beef tallow after bathing with acetone, distill it off, measure the weight, determine the extraction rate (%), and calculate the average value of 10 people. , evaluated based on the following criteria.

(Standard) ◎: Oil removal rate 80% or more ○: Oil removal rate 50% or more but less than 80% △: Oil removal rate 20% or more but less than 50% ×: Oil removal rate less than 20%

(Scale removal effect) Bath water after bathing was sampled, dissolved protein was quantified by the Lowry method, the average value of 10 people was calculated, and evaluation was made according to the following criteria.

(Standard) When the amount of dissolved protein in Comparative Example 1 is 100 ◎: Amount of dissolved protein 200 or more ○: Amount of dissolved protein 150 or more and less than 200 △: Amount of dissolved protein 50 or more and less than 150 ×: Amount of dissolved protein 5
Less than 0

(Bath Feeling) After taking a bath, the participants were asked to score the feeling of bathing as shown below, and the average value of the 10 participants was calculated and evaluated based on the following criteria.

(Score) 2 points: Skin feels very smooth and refreshed. 1 point: Skin feels slightly smoother and refreshed. 0 points: Skin is not smooth or refreshed at all.

(Standard) ◎: 1.5 points or more ○: 1.0 points or more but less than 1.5 points △: 0.5 points or more but less than 1.5 points ×: Less than 0.5 points

[0044] Effect on heat rash Four men and women each with symptoms of heat rash were asked to take a bath repeatedly for 5 minutes once a day for 10 days, and were asked to rate the effect on heat rash as shown below. The total score was calculated and evaluated using the following criteria. The results are shown in Table 3.

(Score) 2 points: Significant symptom improvement effect is observed. 1 point: Some symptom improvement effect is observed. 0 points: No effect observed at all.

(Standard) 4 points or more:○ 2-3 points: △ 0-1 points: ×

■ Effect on acne Soak gauze in bath water and have 4 men and women with acne symptoms soak their affected areas in this gauze for 10 minutes once a day, then wash their faces with water for 10 days. Ta. The participants were asked to score the effect on acne as shown below, and the total score of the four participants was calculated and evaluated based on the following criteria. The results are shown in Table 4.

(Score) 2 points: Significant symptom improvement effect is observed. 1 point: Some symptom improvement effect is observed. 0 points: No effect observed at all.

(Standard) 4 points or more:○ 2-3 points: △ 0-1 points: ×

Table 2

Table 3

Table 4

[Effects of the Invention] As shown in Tables 2, 3, and 4, the bath agent composition of the present invention has an excellent skin cleansing effect, leaving the skin smooth and refreshed after bathing. In addition to providing a refreshing feeling, it has been shown to have a significant symptom-improving effect on skin diseases such as heat rash and acne.

The reason why the bath agent composition of the present invention has the above-mentioned effects is that by making the bath water alkaline with a pH of 8.0 or more, a sufficient effect of removing sebum stains can be obtained, and at the same time, the bath water By becoming alkaline, enzyme activity increases dramatically, and the scale removal effect is also greatly enhanced, and these two effects work synergistically,
It has shown excellent effects.

[0055] The present invention will be explained in more detail below by showing examples of the bath agent composition of the present invention, but the present invention is not limited thereto.

Example 1 Sodium carbonate 20.0 parts by weight Sodium sulfate 50.0 parts by weight Sodium chloride 28.0 parts by weight
Part by weight pancreatin 2.0
Weight part

Example 2 Sodium carbonate 50.0 parts by weight Sodium sulfate 20.0 parts by weight Sodium chloride 28.0 parts by weight
Part by weight pancreatin 2.0
Weight part

Example 3 Sodium carbonate 20.0 parts by weight Sodium sulfate 50.0 parts by weight Sodium chloride 29.5
Part by weight Bioplase Conc 0.5 part by weight

Example 4 Sodium carbonate 50.0 parts by weight Sodium chloride 49.9 parts by weight Bioplase conc 0.1 part by weight

Example 5 Sodium sulfide 50.0 parts by weight Sodium sulfate 49.5 parts by weight Bioplase conc 0.5 parts by weight

Example 6 Sodium carbonate 42.0 parts by weight Sodium hydrogen carbonate 27.0 parts by weight Sodium sulfate 28.2 parts by weight Pancreaticum extract 0.5 parts by weight Pancreatin 1.8 parts by weight Flavor 0
．． 3 parts by weight Yellow No. 202 (1) 0.2 parts by weight

Example 7 Sodium carbonate 72.0 parts Sodium chloride 24.5 parts Bioplase conc 0.5 parts Jojoba oil 0.5 parts by weight
Parts by weight Propylene glycol 1.5 parts by weight Fragrance 0
．． 5 parts by weight Blue No. 1
0.5 parts by weight

Example 8 Sodium carbonate 48.0 parts by weight Magnesium sulfate 49.9 parts by weight Calcium carbonate 1.0 parts by weight Pioprase conc. 0.3 parts by weight Fragrance 0.
4 parts by weight Green No. 204 0
．． 4 parts by weight

30 g/200 liters of each bath agent composition uniformly mixed according to the formulations of Examples 1 to 8 above.
It was dissolved in bath water at 42°C to give a concentration of 150 ppm.

As a result, all of them have an excellent skin cleansing effect, leaving the skin smooth and refreshed after bathing, as well as having a remarkable symptom-improving effect on skin diseases such as heat rash and acne. It was recognized that the

Claims (1)

[Claims] Claim 1: Contains alkaline inorganic salts and proteolytic enzymes, and has a pH of 8.0 to 10.0 when dissolved in bath water.
A bath agent composition characterized in that it exhibits a value.