JPH05509301A - 肺胞界面活性タンパク質 - Google Patents

肺胞界面活性タンパク質

Info

Publication number
JPH05509301A
JPH05509301A JP3510448A JP51044891A JPH05509301A JP H05509301 A JPH05509301 A JP H05509301A JP 3510448 A JP3510448 A JP 3510448A JP 51044891 A JP51044891 A JP 51044891A JP H05509301 A JPH05509301 A JP H05509301A
Authority
JP
Japan
Prior art keywords
array
sequence
protein
amino acids
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP3510448A
Other languages
English (en)
Japanese (ja)
Inventor
ベンソン，ブラッドリー　ジェイ．
ホワイト，ロバート　ティー．
シリング　ジュニア，ジェイムズ　ダブリュー．
バックリー，ダグラス　アイ．
スカーボロー，ロバート　エム．
Original Assignee
バイク　グルデン　ロンバーグ　ケミッシェ　ファブリク　ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイク　グルデン　ロンバーグ　ケミッシェ　ファブリク　ゲーエムベーハー filed Critical バイク　グルデン　ロンバーグ　ケミッシェ　ファブリク　ゲーエムベーハー
Publication of JPH05509301A publication Critical patent/JPH05509301A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP3510448A 1990-05-17 1991-05-17 肺胞界面活性タンパク質 Withdrawn JPH05509301A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/524,360 US5104853A (en) 1984-12-11 1990-05-17 Alveolar surfactant proteins having cys to ser mutations
US524,360 1990-05-17

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2002113971A Division JP2002332298A (ja) 1990-05-17 2002-04-16 肺胞界面活性タンパク質

Publications (1)

Publication Number Publication Date
JPH05509301A true JPH05509301A (ja) 1993-12-22

Family

ID=24088871

Family Applications (3)

Application Number Title Priority Date Filing Date
JP3510448A Withdrawn JPH05509301A (ja) 1990-05-17 1991-05-17 肺胞界面活性タンパク質
JP2002113971A Withdrawn JP2002332298A (ja) 1990-05-17 2002-04-16 肺胞界面活性タンパク質
JP2004323028A Pending JP2005053929A (ja) 1990-05-17 2004-11-05 肺胞界面活性タンパク質

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2002113971A Withdrawn JP2002332298A (ja) 1990-05-17 2002-04-16 肺胞界面活性タンパク質
JP2004323028A Pending JP2005053929A (ja) 1990-05-17 2004-11-05 肺胞界面活性タンパク質

Country Status (5)

Country Link
US (1) US5104853A (https=)
EP (1) EP0538273A4 (https=)
JP (3) JPH05509301A (https=)
CA (1) CA2083177C (https=)
WO (1) WO1991018015A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995141B1 (en) 1990-04-04 2006-02-07 Vertex Pharmaceuticals Incorporated Interleukin 1β protease and interleukin 1β protease inhibitors
AU657701B2 (en) * 1991-08-30 1995-03-23 Vertex Pharmaceuticals Incorporated Interleukin 1beta protease and interleukin 1beta protease inhibitors
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
US6143405A (en) * 1998-06-30 2000-11-07 3M Innovative Properties Company Light colored, electrically conductive coated particles and composites made therefrom
US6395149B1 (en) 1998-06-30 2002-05-28 3M Innovative Properties Company Method of making light colored, electrically conductive coated particles
AU4908799A (en) 1998-07-24 2000-02-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Determination of the hydrophobic pulmonary surfactant protein sp-c
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
DE60032769T2 (de) 1999-06-17 2007-11-22 Nycomed Gmbh Surfactant PROTEIN C ESTER
US7053176B1 (en) 1999-09-16 2006-05-30 Altana Pharma Ag Combination of C1-INH and lung surfactant for the treatment of respiratory disorders
AU2002338882B2 (en) 2001-10-11 2008-04-03 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Novel use of pulmonary surfactant
CA2575513C (en) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
WO2010068754A2 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
JP7173452B2 (ja) * 2017-03-07 2022-11-16 キリンホールディングス株式会社 カルボキシル末端アミノ酸の分析方法
US12606609B2 (en) 2020-01-28 2026-04-21 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties
AU2021255702A1 (en) * 2020-04-17 2022-11-17 Regeneron Pharmaceuticals, Inc. Modified CCR polypeptides and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853332A (en) * 1982-10-19 1989-08-01 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins
ATE163013T1 (de) * 1987-11-04 1998-02-15 Byk Gulden Lomberg Chem Fab Alveolare oberflächenaktive proteine

Also Published As

Publication number Publication date
WO1991018015A1 (en) 1991-11-28
JP2005053929A (ja) 2005-03-03
CA2083177C (en) 2002-02-26
JP2002332298A (ja) 2002-11-22
EP0538273A1 (en) 1993-04-28
CA2083177A1 (en) 1991-11-18
EP0538273A4 (en) 1993-06-16
US5104853A (en) 1992-04-14

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Effective date: 20050913

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