JPH0530439B2 - - Google Patents

Info

Publication number
JPH0530439B2
JPH0530439B2 JP63190160A JP19016088A JPH0530439B2 JP H0530439 B2 JPH0530439 B2 JP H0530439B2 JP 63190160 A JP63190160 A JP 63190160A JP 19016088 A JP19016088 A JP 19016088A JP H0530439 B2 JPH0530439 B2 JP H0530439B2
Authority
JP
Japan
Prior art keywords
reaction
column
immobilized
organic solvent
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63190160A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0239895A (ja
Inventor
Ryuichi Matsuno
Kazuhiro Nakanishi
Akira Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiwa Kasei KK
Original Assignee
Daiwa Kasei KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiwa Kasei KK filed Critical Daiwa Kasei KK
Priority to JP19016088A priority Critical patent/JPH0239895A/ja
Publication of JPH0239895A publication Critical patent/JPH0239895A/ja
Publication of JPH0530439B2 publication Critical patent/JPH0530439B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
JP19016088A 1988-07-28 1988-07-28 ジペプチドの連続製造法 Granted JPH0239895A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP19016088A JPH0239895A (ja) 1988-07-28 1988-07-28 ジペプチドの連続製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19016088A JPH0239895A (ja) 1988-07-28 1988-07-28 ジペプチドの連続製造法

Publications (2)

Publication Number Publication Date
JPH0239895A JPH0239895A (ja) 1990-02-08
JPH0530439B2 true JPH0530439B2 (enExample) 1993-05-10

Family

ID=16253424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19016088A Granted JPH0239895A (ja) 1988-07-28 1988-07-28 ジペプチドの連続製造法

Country Status (1)

Country Link
JP (1) JPH0239895A (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020015742A (ko) * 2000-08-23 2002-03-02 신철수 단백질 가수분해효소를 이용한 아스파탐 전구체의 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6229996A (ja) * 1985-07-30 1987-02-07 Hiroshi Ooshima Ｎ−保護ｌ−アスパルチル−ｌ−フエニルアラニン低級アルキルエステルの製造方法

Also Published As

Publication number Publication date
JPH0239895A (ja) 1990-02-08

Similar Documents

Publication Publication Date Title
US4284721A (en) Method for manufacturing dipeptides
Oyama et al. [46] Production of aspartame by immobilized thermoase
KR900004070B1 (ko) 펩티드의 합성 및 분리를 위한 효소막법
Cantacuzene et al. Synthesis of amino acid esters by papain
Kimura et al. Enzymatic synthesis of the precursor of Leu-enkephalin in water-immiscible organic solvent systems
KR930002966B1 (ko) 디펩티드의 제조방법
EP0149594A2 (en) Enzymatic coupling of n-formyl amino acids and/or peptide residues
Nagayasu et al. Synthesis of dipeptide precursors with an immobilized thermolysin in ethyl acetate
JPH0530439B2 (enExample)
Miyanaga et al. Synthesis of aspartame precursor with an immobilized thermolysin in mixed organic solvents
JPS63502639A (ja) ペプチドの合成と分離のための酵素的膜方法
IE52242B1 (en) Preparation of amino protected-l-aspartyl-l-phenylalanine alkyl ester
JPS621719B2 (enExample)
Stepanov Proteinases as catalysts in peptide synthesis
Vulfson et al. L-Dopa ester synthesis catalyzed by α-chymotrypsin in organic solvents
CA1320923C (en) Enzyme mediated coupling reactions
JPS6033840B2 (ja) ジペプチド類の製造法
US20040137559A1 (en) Process for producing N-formylamino acid and use thereof
CA1337936C (en) Vibriolysin coupling process
Nakaoka et al. Papain-catalyzed synthesis of aspartame precursor: A comparison with thermolysin
Cramer et al. Peptide synthesis with immobilized carboxypeptidase Y
JPH06237784A (ja) オリゴペプチドの合成法
JPH0423996A (ja) トリペプチド誘導体の連続製造法
Lee et al. Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
JPH0634745B2 (ja) Ｎ−保護ペプチドの酵素的合成法