JPH0477B2 - - Google Patents

Info

Publication number
JPH0477B2
JPH0477B2 JP5467984A JP5467984A JPH0477B2 JP H0477 B2 JPH0477 B2 JP H0477B2 JP 5467984 A JP5467984 A JP 5467984A JP 5467984 A JP5467984 A JP 5467984A JP H0477 B2 JPH0477 B2 JP H0477B2
Authority
JP
Japan
Prior art keywords
methyl
compound
dihydro
carboxylic acid
quinolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP5467984A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60197684A (ja
Inventor
Junichi Matsumoto
Hiroshi Egawa
Koshi Myamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Priority to JP5467984A priority Critical patent/JPS60197684A/ja
Publication of JPS60197684A publication Critical patent/JPS60197684A/ja
Publication of JPH0477B2 publication Critical patent/JPH0477B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP5467984A 1984-03-21 1984-03-21 ベンゾ〔ａ〕キノリジン誘導体およびその塩 Granted JPS60197684A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5467984A JPS60197684A (ja) 1984-03-21 1984-03-21 ベンゾ〔ａ〕キノリジン誘導体およびその塩

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5467984A JPS60197684A (ja) 1984-03-21 1984-03-21 ベンゾ〔ａ〕キノリジン誘導体およびその塩

Publications (2)

Publication Number Publication Date
JPS60197684A JPS60197684A (ja) 1985-10-07
JPH0477B2 true JPH0477B2 (e) 1992-01-06

Family

ID=12977472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5467984A Granted JPS60197684A (ja) 1984-03-21 1984-03-21 ベンゾ〔ａ〕キノリジン誘導体およびその塩

Country Status (1)

Country Link
JP (1) JPS60197684A (e)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10821103B2 (en) 2016-11-07 2020-11-03 Arbutus Biopharma Corporation Substituted pyridinone-containing trycyclic compounds, and methods using same
US11505551B2 (en) 2018-04-12 2022-11-22 Arbutus Biopharma Corporation Methods for preparing substituted pyridinone-containing tricyclic compounds
US11702427B2 (en) 2018-03-12 2023-07-18 Arbutus Biopharma Corporation Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12014500429A1 (en) * 2011-08-29 2014-04-14 Ptc Therapeutics Inc Antibacterial compounds and methods for use
EA201691261A1 (ru) * 2014-01-30 2016-11-30 Ф. Хоффманн-Ля Рош Аг Новые дигидрохинолизиноны для лечения и профилактики инфекции, вызванной вирусом гепатита b
RU2016146365A (ru) 2014-05-13 2018-06-19 Ф. Хоффманн-Ля Рош Аг Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b
US9637485B2 (en) * 2014-11-03 2017-05-02 Hoffmann-La Roche Inc. 6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
CN107207505B (zh) * 2015-02-11 2018-12-14 豪夫迈·罗氏有限公司 治疗和预防乙型肝炎病毒感染的 2-氧代-6,7-二氢苯并[a]喹嗪-3-甲酸衍生物
WO2016177655A1 (en) 2015-05-04 2016-11-10 F. Hoffmann-La Roche Ag Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections
JP6598974B2 (ja) * 2015-07-21 2019-10-30 エフ．ホフマン−ラ ロシュ アーゲー Ｂ型肝炎ウイルス感染症の治療および予防のための新規な三環式４−ピリドン−３−カルボン酸誘導体
WO2017016960A1 (en) * 2015-07-24 2017-02-02 F. Hoffmann-La Roche Ag Process for the preparation of (6s)-6-alkyl-10-alkoxy-9-(substituted alkoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid analogues
JP6506880B2 (ja) 2015-07-27 2019-04-24 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｂ型肝炎ウィルス感染症の治療および予防のための新規な四環式４−オキソ−ピリジン−３−カルボン酸誘導体
JP6559324B2 (ja) 2015-07-28 2019-08-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｂ型肝炎ウイルス感染の治療及び予防用の新規６，７−ジヒドロピリド［２，１−ａ］フタラジン−２−オン類
CN107759585A (zh) * 2016-07-29 2018-03-06 银杏树药业(苏州)有限公司 一种异喹啉类化合物及其药用组合物和作为抗病毒药物的应用
CN106810548B (zh) * 2017-01-13 2019-02-15 苏州爱科百发生物医药技术有限公司 一种二氢异喹啉类化合物

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10821103B2 (en) 2016-11-07 2020-11-03 Arbutus Biopharma Corporation Substituted pyridinone-containing trycyclic compounds, and methods using same
US11013726B2 (en) 2016-11-07 2021-05-25 Arbutus Biopharma Corporation Substituted pyridinone-containing trycyclic compounds, and methods using same
US11702427B2 (en) 2018-03-12 2023-07-18 Arbutus Biopharma Corporation Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same
US11505551B2 (en) 2018-04-12 2022-11-22 Arbutus Biopharma Corporation Methods for preparing substituted pyridinone-containing tricyclic compounds

Also Published As

Publication number Publication date
JPS60197684A (ja) 1985-10-07

Similar Documents

Publication Publication Date Title
US3700673A (en) 3-4-dihydrobenzo(b) (1,7)naphthyridin-1(2h)-ones
Matsumoto et al. 1, 4-Dihydro-4-oxopyridinecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1, 6, 7-trisubstituted 1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent
JPH0477B2 (e)
SU831077A3 (ru) Способ получени 1,2-дигидрохино-ли-2-OHOB или иХ СОлЕй (ЕгО ВАРиАН-Ты)
JPH0714918B2 (ja) 新規５−置換キノロン誘導体、そのエステルおよびその塩
US3336307A (en) Heteroaroyl-benzindolyl acids
JP2004500324A (ja) ピペラジン環含有化合物の新規の合成及び結晶化
US2919271A (en) 3-amino-1, 2-dihydro-3h-pyrido [3, 2, 1-kl]-phenothiazines
CA2199645C (en) Methods for the manufacture of quinolone carboxylic acids derivatives and intermediates thereof
JPH0116837B2 (e)
US6576764B2 (en) Synthesis and crystallization of piperazine ring-containing compounds
WO1997013753A1 (en) Process for the preparation of anti-malarial drugs
JPH0373548B2 (e)
EP0248876B1 (en) Process for the preparation of 1-methylamino-quinoline-carboxylic acid derivatives
US5561233A (en) Process for the preparation of an intermediate of a benzo[a]quinolizinone derivative
AU627609B2 (en) New quinoline derivatives and process for the preparation thereof
WO1991001315A1 (en) New quinoline derivatives and process for the preparation thereof
JPS62201869A (ja) キノリン誘導体の製造法
US3320245A (en) Derivatives of phenothiazine-10-glyoxylic acids and intermediates in the preparationthereof
JPH0373549B2 (e)
HUT67395A (en) Method for the n-cyclopropylation of primary and secondary aromatic amines
US20040176591A1 (en) Novel synthesis and crystallization of peperazine ring-containing compounds
JPS5929685A (ja) ７−置換フエニルピペラジノ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
KR800001685B1 (ko) 피리도[2,3-d]피리미딘 유도체의 제조방법
JP2966893B2 (ja) 新規キノロン―３―カルバルデヒド誘導体およびその塩