JPH0469636B2 - - Google Patents

Info

Publication number
JPH0469636B2
JPH0469636B2 JP59502183A JP50218384A JPH0469636B2 JP H0469636 B2 JPH0469636 B2 JP H0469636B2 JP 59502183 A JP59502183 A JP 59502183A JP 50218384 A JP50218384 A JP 50218384A JP H0469636 B2 JPH0469636 B2 JP H0469636B2
Authority
JP
Japan
Prior art keywords
platinum
groups
water
bis
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59502183A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60501260A (ja
Inventor
Piitaa Jei Junia Andorurisu
Hooru Shuwarutsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANDORURISU RISAACHI CORP
Original Assignee
ANDORURISU RISAACHI CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANDORURISU RISAACHI CORP filed Critical ANDORURISU RISAACHI CORP
Publication of JPS60501260A publication Critical patent/JPS60501260A/ja
Publication of JPH0469636B2 publication Critical patent/JPH0469636B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/418—Preparation of metal complexes containing carboxylic acid moieties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/04—Saturated compounds having a carboxyl group bound to a three or four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/28—Unsaturated compounds polycyclic
    • C07C61/29—Unsaturated compounds polycyclic having a carboxyl group bound to a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/313—Monocyclic acids containing more than three carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
    • C07C63/40—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings containing three or more carboxyl groups all bound to carbon atoms of the condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP59502183A 1983-05-10 1984-05-10 抗腫瘍剤としてのビス−白金錯塩 Granted JPS60501260A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49317783A 1983-05-10 1983-05-10
US493177 1983-05-10

Publications (2)

Publication Number Publication Date
JPS60501260A JPS60501260A (ja) 1985-08-08
JPH0469636B2 true JPH0469636B2 (OSRAM) 1992-11-06

Family

ID=23959205

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59502183A Granted JPS60501260A (ja) 1983-05-10 1984-05-10 抗腫瘍剤としてのビス−白金錯塩

Country Status (9)

Country Link
EP (1) EP0137900B1 (OSRAM)
JP (1) JPS60501260A (OSRAM)
AT (1) ATE52517T1 (OSRAM)
AU (1) AU558747B2 (OSRAM)
CA (1) CA1241648A (OSRAM)
DE (1) DE3482182D1 (OSRAM)
IL (1) IL71804A (OSRAM)
WO (1) WO1984004524A1 (OSRAM)
ZA (1) ZA843515B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328218D0 (en) * 1983-10-21 1983-11-23 Johnson Matthey Plc Oral compositions
US4680308A (en) * 1985-12-26 1987-07-14 Andrulis Research Corporation Stable soluble 1,2-diaminocyclohexane platinum complexes
WO1997033894A1 (fr) * 1996-03-11 1997-09-18 Debiopharm Sa Complexes de platine dinucleaires, procede pour leur preparation et compositions pharmaceutiques en contenant
USD1066749S1 (en) * 2023-09-14 2025-03-11 Underwater Gardens International, S.L. Artificial reef

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833570A (en) * 1970-08-12 1974-09-03 Bristol Myers Co 7-(3-substituted-1,2,4-oxadiazole-5-one-4-acetamido)cephalosporanic acids and derivatives thereof
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
US4230631A (en) * 1977-10-19 1980-10-28 Johnson, Matthey & Co., Limited Platinum coordination compounds
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
US4283342A (en) * 1980-01-31 1981-08-11 University Of Delaware Anticancer agents and methods of manufacture
GR75598B (OSRAM) * 1980-04-29 1984-08-01 Sanofi Sa
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes
ZA815852B (en) * 1980-09-03 1982-08-25 Johnson Matthey Plc Co-ordination compound of platinum

Also Published As

Publication number Publication date
EP0137900B1 (en) 1990-05-09
ATE52517T1 (de) 1990-05-15
IL71804A0 (en) 1984-09-30
EP0137900A1 (en) 1985-04-24
CA1241648A (en) 1988-09-06
AU558747B2 (en) 1987-02-05
IL71804A (en) 1989-06-30
AU3011984A (en) 1984-12-04
DE3482182D1 (de) 1990-06-13
JPS60501260A (ja) 1985-08-08
WO1984004524A1 (en) 1984-11-22
ZA843515B (en) 1985-01-30

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