JPH0456805B2 - - Google Patents
Info
- Publication number
- JPH0456805B2 JPH0456805B2 JP11828384A JP11828384A JPH0456805B2 JP H0456805 B2 JPH0456805 B2 JP H0456805B2 JP 11828384 A JP11828384 A JP 11828384A JP 11828384 A JP11828384 A JP 11828384A JP H0456805 B2 JPH0456805 B2 JP H0456805B2
- Authority
- JP
- Japan
- Prior art keywords
- crosslinked
- cells
- viscosity
- cancer
- physiological saline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 150000004692 metal hydroxides Chemical class 0.000 description 1
- 208000037819 metastatic cancer Diseases 0.000 description 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11828384A JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11828384A JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6117A JPS6117A (ja) | 1986-01-06 |
| JPH0456805B2 true JPH0456805B2 (enExample) | 1992-09-09 |
Family
ID=14732832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11828384A Granted JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6117A (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262403A (en) * | 1986-03-10 | 1993-11-16 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II |
| US4746504A (en) * | 1986-03-14 | 1988-05-24 | Bio-Technology General Corp. | Heavy metal salts of hyaluronic acid and their use as antimicrobial agents |
| WO1988001280A1 (en) * | 1986-08-21 | 1988-02-25 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion |
| IT1219587B (it) * | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| CA1340994C (en) * | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| AU7478191A (en) * | 1990-03-05 | 1991-10-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Endogenous, suramin-induced, sulfated glycosaminoglycans as anti-cancer agents in humans |
| ATE148713T1 (de) * | 1990-07-24 | 1997-02-15 | Seikagaku Kogyo Co Ltd | Glykosaminoglykan gemischt mit phospholipid oder lipid, seine herstellung und krebszellenmetastaseninhibitor |
| US5733892A (en) * | 1990-07-24 | 1998-03-31 | Seikagaku Corporation | Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same |
| US5639738A (en) * | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
| US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| WO1994007505A1 (en) * | 1991-07-03 | 1994-04-14 | Norpharmco Inc. | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US6103704A (en) * | 1991-07-03 | 2000-08-15 | Hyal Pharmaceutical Corporation | Therapeutic methods using hyaluronic acid |
| US5990095A (en) * | 1991-07-03 | 1999-11-23 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US5817644A (en) * | 1991-07-03 | 1998-10-06 | Hyal Pharmaceutical Corporation | Targeting of dosages of medicine and therapeutic agents |
| US5942498A (en) * | 1992-02-20 | 1999-08-24 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
| CA2061567C (en) * | 1992-02-20 | 1998-02-03 | Rudolf E. Falk | Use of hyaluronic acid to repair ischemia reperfusion damage |
| AU6362594A (en) * | 1993-03-10 | 1994-09-26 | Miles Inc. | Hyaluronic acid used as a cancer treatment |
| CA2175282A1 (en) * | 1996-04-29 | 1997-10-30 | Rudolf Edgar Falk | Use of forms of hyaluronic acid (ha) for the treatment of cancer |
| AU4572797A (en) * | 1996-10-15 | 1998-05-11 | Toray Industries, Inc. | Cervical canal maturing agent |
| GB9716219D0 (en) * | 1997-07-31 | 1997-10-08 | Geistlich Soehne Ag | Prevention of metastases |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US7151099B2 (en) | 1998-07-31 | 2006-12-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases |
| CN100374163C (zh) | 1999-01-13 | 2008-03-12 | 阿尔凯米亚肿瘤学私人有限公司 | 增强药物功效的组合物 |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US7345039B2 (en) | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| AUPQ879500A0 (en) * | 2000-07-14 | 2000-08-10 | Meditech Research Limited | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease |
| US9066919B2 (en) | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
| TW574301B (en) * | 2001-05-02 | 2004-02-01 | Ind Tech Res Inst | Manufacturing method of epoxide crosslinked polysaccharides matrix |
| US6806259B2 (en) * | 2001-12-21 | 2004-10-19 | Soft Gel Technologies, Inc. | Hyaluronic Acid in soft gel form |
| ITPD20020003A1 (it) * | 2002-01-11 | 2003-07-11 | Fidia Advanced Biopolymers Srl | Biomateriali a base di acido ialuronico come terapia anti-angiogenicanella cura dei tumori. |
| ITMI20021866A1 (it) * | 2002-08-30 | 2004-02-29 | Luigi Allegra | Preparazione farmaceutica in forma colloidale utile nella cura delle affezioni cutanee. |
| JP5465431B2 (ja) | 2005-07-27 | 2014-04-09 | アルケミア オンコロジー ピーティーワイ リミテッド | ヒアルロナンを用いる治療プロトコル |
| MY149606A (en) | 2005-09-07 | 2013-09-13 | Alchemia Oncology Pty Ltd | Therapeutic compositions comprising hyaluronan and therapeutic antibodies as well as methods of treatment |
| EP2063859B1 (en) | 2006-09-13 | 2017-01-18 | Enhance Skin Products Inc. | Cosmetic composition for the treatment of skin and methods thereof |
-
1984
- 1984-06-11 JP JP11828384A patent/JPS6117A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6117A (ja) | 1986-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |