JPH04338381A - ２，２−ジメチル−２，３−ジヒドロベンゾフラン−７−カルボン酸類の製造方法及びその中間体 - Google Patents

２，２−ジメチル−２，３−ジヒドロベンゾフラン−７−カルボン酸類の製造方法及びその中間体

Info

Publication number
JPH04338381A
JPH04338381A JP4049416A JP4941692A JPH04338381A JP H04338381 A JPH04338381 A JP H04338381A JP 4049416 A JP4049416 A JP 4049416A JP 4941692 A JP4941692 A JP 4941692A JP H04338381 A JPH04338381 A JP H04338381A
Authority
JP
Japan
Prior art keywords
formula
acid
methyl
liters
propenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4049416A
Other languages
English (en)
Japanese (ja)
Inventor
Christopher Randall Schmid
クリストファー・ランドール・シュミット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPH04338381A publication Critical patent/JPH04338381A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP4049416A 1991-03-07 1992-03-06 ２，２−ジメチル−２，３−ジヒドロベンゾフラン−７−カルボン酸類の製造方法及びその中間体 Pending JPH04338381A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US666279 1991-03-07
US07/666,279 US5142069A (en) 1991-03-07 1991-03-07 Process of preparing 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acids

Publications (1)

Publication Number Publication Date
JPH04338381A true JPH04338381A (ja) 1992-11-25

Family

ID=24673565

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4049416A Pending JPH04338381A (ja) 1991-03-07 1992-03-06 ２，２−ジメチル−２，３−ジヒドロベンゾフラン−７−カルボン酸類の製造方法及びその中間体

Country Status (16)

Country Link
US (1) US5142069A (enExample)
EP (1) EP0502735B1 (enExample)
JP (1) JPH04338381A (enExample)
KR (1) KR100193973B1 (enExample)
AT (1) ATE127461T1 (enExample)
BR (1) BR9200768A (enExample)
CA (1) CA2062329A1 (enExample)
DE (1) DE69204497T2 (enExample)
DK (1) DK0502735T3 (enExample)
ES (1) ES2078652T3 (enExample)
GR (1) GR3017875T3 (enExample)
HU (1) HU212786B (enExample)
IE (1) IE67382B1 (enExample)
IL (1) IL101149A (enExample)
MX (1) MX9200962A (enExample)
TW (1) TW198014B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860619A (en) * 1969-05-09 1975-01-14 Novo Terapeutisk Labor As Sulphonylurea derivatives
WO1984003281A1 (en) * 1983-02-19 1984-08-30 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4921982A (en) * 1988-07-21 1990-05-01 Eli Lilly And Company 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists

Also Published As

Publication number Publication date
DE69204497T2 (de) 1996-03-21
HU9200745D0 (en) 1992-05-28
US5142069A (en) 1992-08-25
IE920737A1 (en) 1992-09-09
IE67382B1 (en) 1996-03-20
BR9200768A (pt) 1992-11-17
EP0502735A1 (en) 1992-09-09
ATE127461T1 (de) 1995-09-15
HU212786B (en) 1996-11-28
DE69204497D1 (de) 1995-10-12
TW198014B (enExample) 1993-01-11
IL101149A0 (en) 1992-11-15
IL101149A (en) 1996-09-12
KR920018038A (ko) 1992-10-21
HUT61008A (en) 1992-11-30
GR3017875T3 (en) 1996-01-31
EP0502735B1 (en) 1995-09-06
ES2078652T3 (es) 1995-12-16
DK0502735T3 (da) 1996-04-09
CA2062329A1 (en) 1992-09-08
MX9200962A (es) 1992-09-01
KR100193973B1 (ko) 1999-06-15

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Legal Events

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A02 Decision of refusal

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Effective date: 20000725