DK0502735T3 - Fremgangsmåde og mellemprodukter til fremstilling af 2,2-dimethyl-2,3-dihydrobenzofuran-7- carboxylsyrer - Google Patents

Fremgangsmåde og mellemprodukter til fremstilling af 2,2-dimethyl-2,3-dihydrobenzofuran-7- carboxylsyrer

Info

Publication number
DK0502735T3
DK0502735T3 DK92301904.6T DK92301904T DK0502735T3 DK 0502735 T3 DK0502735 T3 DK 0502735T3 DK 92301904 T DK92301904 T DK 92301904T DK 0502735 T3 DK0502735 T3 DK 0502735T3
Authority
DK
Denmark
Prior art keywords
dihydrobenzofuran
intermediates
dimethyl
carboxylic acids
preparation
Prior art date
Application number
DK92301904.6T
Other languages
English (en)
Inventor
Christopher Randall Schmid
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0502735T3 publication Critical patent/DK0502735T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cosmetics (AREA)
DK92301904.6T 1991-03-07 1992-03-05 Fremgangsmåde og mellemprodukter til fremstilling af 2,2-dimethyl-2,3-dihydrobenzofuran-7- carboxylsyrer DK0502735T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/666,279 US5142069A (en) 1991-03-07 1991-03-07 Process of preparing 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acids

Publications (1)

Publication Number Publication Date
DK0502735T3 true DK0502735T3 (da) 1996-04-09

Family

ID=24673565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92301904.6T DK0502735T3 (da) 1991-03-07 1992-03-05 Fremgangsmåde og mellemprodukter til fremstilling af 2,2-dimethyl-2,3-dihydrobenzofuran-7- carboxylsyrer

Country Status (16)

Country Link
US (1) US5142069A (da)
EP (1) EP0502735B1 (da)
JP (1) JPH04338381A (da)
KR (1) KR100193973B1 (da)
AT (1) ATE127461T1 (da)
BR (1) BR9200768A (da)
CA (1) CA2062329A1 (da)
DE (1) DE69204497T2 (da)
DK (1) DK0502735T3 (da)
ES (1) ES2078652T3 (da)
GR (1) GR3017875T3 (da)
HU (1) HU212786B (da)
IE (1) IE67382B1 (da)
IL (1) IL101149A (da)
MX (1) MX9200962A (da)
TW (1) TW198014B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860619A (en) * 1969-05-09 1975-01-14 Novo Terapeutisk Labor As Sulphonylurea derivatives
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4921982A (en) * 1988-07-21 1990-05-01 Eli Lilly And Company 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists

Also Published As

Publication number Publication date
DE69204497T2 (de) 1996-03-21
IL101149A0 (en) 1992-11-15
MX9200962A (es) 1992-09-01
HU9200745D0 (en) 1992-05-28
GR3017875T3 (en) 1996-01-31
IL101149A (en) 1996-09-12
EP0502735A1 (en) 1992-09-09
JPH04338381A (ja) 1992-11-25
ATE127461T1 (de) 1995-09-15
IE67382B1 (en) 1996-03-20
CA2062329A1 (en) 1992-09-08
TW198014B (da) 1993-01-11
KR920018038A (ko) 1992-10-21
KR100193973B1 (ko) 1999-06-15
DE69204497D1 (de) 1995-10-12
ES2078652T3 (es) 1995-12-16
IE920737A1 (en) 1992-09-09
HUT61008A (en) 1992-11-30
EP0502735B1 (en) 1995-09-06
US5142069A (en) 1992-08-25
BR9200768A (pt) 1992-11-17
HU212786B (en) 1996-11-28

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