ES2078652T3 - Procedimiento y compuestos intermedios para acidos 2,2-dimetil-2,3-dihidrobenzofuran-7-carboxilicos. - Google Patents

Procedimiento y compuestos intermedios para acidos 2,2-dimetil-2,3-dihidrobenzofuran-7-carboxilicos.

Info

Publication number
ES2078652T3
ES2078652T3 ES92301904T ES92301904T ES2078652T3 ES 2078652 T3 ES2078652 T3 ES 2078652T3 ES 92301904 T ES92301904 T ES 92301904T ES 92301904 T ES92301904 T ES 92301904T ES 2078652 T3 ES2078652 T3 ES 2078652T3
Authority
ES
Spain
Prior art keywords
dihydrobenzofuran
dimethyl
carboxylic acids
procedure
intermediate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92301904T
Other languages
English (en)
Inventor
Christopher Randall Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2078652T3 publication Critical patent/ES2078652T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION PROPORCIONA UN PROCESO E INTERMEDIARIOS PARA PREPARAR ACIDOS 2,2-DIMETIL-2,3-DIHIDROBENZOFURAN-7-CARBOXILICOS.
ES92301904T 1991-03-07 1992-03-05 Procedimiento y compuestos intermedios para acidos 2,2-dimetil-2,3-dihidrobenzofuran-7-carboxilicos. Expired - Lifetime ES2078652T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/666,279 US5142069A (en) 1991-03-07 1991-03-07 Process of preparing 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acids

Publications (1)

Publication Number Publication Date
ES2078652T3 true ES2078652T3 (es) 1995-12-16

Family

ID=24673565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92301904T Expired - Lifetime ES2078652T3 (es) 1991-03-07 1992-03-05 Procedimiento y compuestos intermedios para acidos 2,2-dimetil-2,3-dihidrobenzofuran-7-carboxilicos.

Country Status (16)

Country Link
US (1) US5142069A (es)
EP (1) EP0502735B1 (es)
JP (1) JPH04338381A (es)
KR (1) KR100193973B1 (es)
AT (1) ATE127461T1 (es)
BR (1) BR9200768A (es)
CA (1) CA2062329A1 (es)
DE (1) DE69204497T2 (es)
DK (1) DK0502735T3 (es)
ES (1) ES2078652T3 (es)
GR (1) GR3017875T3 (es)
HU (1) HU212786B (es)
IE (1) IE67382B1 (es)
IL (1) IL101149A (es)
MX (1) MX9200962A (es)
TW (1) TW198014B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860619A (en) * 1969-05-09 1975-01-14 Novo Terapeutisk Labor As Sulphonylurea derivatives
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4921982A (en) * 1988-07-21 1990-05-01 Eli Lilly And Company 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists

Also Published As

Publication number Publication date
IL101149A0 (en) 1992-11-15
HU9200745D0 (en) 1992-05-28
DE69204497T2 (de) 1996-03-21
IL101149A (en) 1996-09-12
CA2062329A1 (en) 1992-09-08
ATE127461T1 (de) 1995-09-15
DE69204497D1 (de) 1995-10-12
DK0502735T3 (da) 1996-04-09
HUT61008A (en) 1992-11-30
IE67382B1 (en) 1996-03-20
EP0502735B1 (en) 1995-09-06
TW198014B (es) 1993-01-11
US5142069A (en) 1992-08-25
KR920018038A (ko) 1992-10-21
MX9200962A (es) 1992-09-01
EP0502735A1 (en) 1992-09-09
IE920737A1 (en) 1992-09-09
BR9200768A (pt) 1992-11-17
JPH04338381A (ja) 1992-11-25
KR100193973B1 (ko) 1999-06-15
GR3017875T3 (en) 1996-01-31
HU212786B (en) 1996-11-28

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