JPH0417932B2 - - Google Patents
Info
- Publication number
- JPH0417932B2 JPH0417932B2 JP60504334A JP50433485A JPH0417932B2 JP H0417932 B2 JPH0417932 B2 JP H0417932B2 JP 60504334 A JP60504334 A JP 60504334A JP 50433485 A JP50433485 A JP 50433485A JP H0417932 B2 JPH0417932 B2 JP H0417932B2
- Authority
- JP
- Japan
- Prior art keywords
- nifedipine
- mixture
- release
- treatment
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Cosmetics (AREA)
- Steering Control In Accordance With Driving Conditions (AREA)
- Electroplating And Plating Baths Therefor (AREA)
- Surgical Instruments (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22678/84A IT1178511B (it) | 1984-09-14 | 1984-09-14 | Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio |
| IT22678A/84 | 1984-09-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62500660A JPS62500660A (ja) | 1987-03-19 |
| JPH0417932B2 true JPH0417932B2 (enEXAMPLES) | 1992-03-26 |
Family
ID=11199169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60504334A Granted JPS62500660A (ja) | 1984-09-14 | 1985-09-04 | 活性物質の制御放出を伴うニフェディピンを基礎とする内服用固体の製造方法 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0226588B1 (enEXAMPLES) |
| JP (1) | JPS62500660A (enEXAMPLES) |
| AT (1) | ATE61733T1 (enEXAMPLES) |
| AU (1) | AU588258B2 (enEXAMPLES) |
| CA (1) | CA1253079A (enEXAMPLES) |
| DE (1) | DE3582251D1 (enEXAMPLES) |
| DK (1) | DK172710B1 (enEXAMPLES) |
| ES (1) | ES8702137A1 (enEXAMPLES) |
| FI (1) | FI87991C (enEXAMPLES) |
| IE (1) | IE58490B1 (enEXAMPLES) |
| IT (1) | IT1178511B (enEXAMPLES) |
| NO (1) | NO171887C (enEXAMPLES) |
| PT (1) | PT81113B (enEXAMPLES) |
| WO (1) | WO1986001717A1 (enEXAMPLES) |
| YU (1) | YU45988B (enEXAMPLES) |
| ZA (1) | ZA856862B (enEXAMPLES) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1187751B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute |
| SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
| DK173505B1 (da) * | 1987-02-20 | 2001-01-15 | Pharmatec Internat S R L | Fremgangsmåde til fremstilling af en diltiazempellet med langsom afgivelse og anvendelse af således fremstillede pelleter t |
| GB8722306D0 (en) * | 1987-09-22 | 1987-10-28 | Aps Research Ltd | Sustained-release formulation |
| GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
| HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
| US5122384A (en) * | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
| WO1994005262A1 (en) * | 1992-09-10 | 1994-03-17 | F.H. Faulding & Co. Limited | Sustained release matrix composition |
| US6077533A (en) * | 1994-05-25 | 2000-06-20 | Purdue Pharma L.P. | Powder-layered oral dosage forms |
| US7060293B1 (en) | 1994-05-25 | 2006-06-13 | Purdue Pharma | Powder-layered oral dosage forms |
| DK0800392T3 (da) * | 1994-12-29 | 2002-03-18 | Shire Deutschland Gmbh & Co Kg | Farmaceutiske præparater med indhold af nifedipin samt fremgangsmåde til fremstilling deraf |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2453642A1 (fr) * | 1979-04-12 | 1980-11-07 | Sanofi Sa | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotoxine |
| DE3033919A1 (de) * | 1980-09-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
| DE3433239A1 (de) * | 1984-09-11 | 1986-03-20 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
-
1984
- 1984-09-14 IT IT22678/84A patent/IT1178511B/it active
-
1985
- 1985-09-04 EP EP85904808A patent/EP0226588B1/en not_active Expired - Lifetime
- 1985-09-04 JP JP60504334A patent/JPS62500660A/ja active Granted
- 1985-09-04 AT AT85904808T patent/ATE61733T1/de not_active IP Right Cessation
- 1985-09-04 DE DE8585904808T patent/DE3582251D1/de not_active Expired - Lifetime
- 1985-09-04 WO PCT/EP1985/000481 patent/WO1986001717A1/en active IP Right Grant
- 1985-09-04 AU AU49594/85A patent/AU588258B2/en not_active Ceased
- 1985-09-06 ZA ZA856862A patent/ZA856862B/xx unknown
- 1985-09-12 CA CA000490628A patent/CA1253079A/en not_active Expired
- 1985-09-12 PT PT81113A patent/PT81113B/pt unknown
- 1985-09-13 ES ES547707A patent/ES8702137A1/es not_active Expired
- 1985-09-13 YU YU143985A patent/YU45988B/sh unknown
- 1985-09-13 IE IE226285A patent/IE58490B1/en not_active IP Right Cessation
-
1986
- 1986-05-07 NO NO86861845A patent/NO171887C/no not_active IP Right Cessation
- 1986-05-13 DK DK198602221A patent/DK172710B1/da not_active IP Right Cessation
-
1987
- 1987-03-13 FI FI871116A patent/FI87991C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0226588A1 (en) | 1987-07-01 |
| WO1986001717A1 (en) | 1986-03-27 |
| ES8702137A1 (es) | 1987-01-16 |
| IT8422678A0 (it) | 1984-09-14 |
| DK222186D0 (da) | 1986-05-13 |
| FI87991B (fi) | 1992-12-15 |
| DK222186A (da) | 1986-05-13 |
| IE58490B1 (en) | 1993-09-22 |
| FI87991C (fi) | 1993-03-25 |
| CA1253079A (en) | 1989-04-25 |
| IE852262L (en) | 1986-03-14 |
| JPS62500660A (ja) | 1987-03-19 |
| FI871116A7 (fi) | 1987-03-13 |
| FI871116A0 (fi) | 1987-03-13 |
| NO171887C (no) | 1993-05-19 |
| DK172710B1 (da) | 1999-06-07 |
| DE3582251D1 (de) | 1991-04-25 |
| AU588258B2 (en) | 1989-09-14 |
| PT81113A (en) | 1985-10-01 |
| ZA856862B (en) | 1986-05-28 |
| EP0226588B1 (en) | 1991-03-20 |
| NO861845L (no) | 1986-05-07 |
| PT81113B (pt) | 1987-10-20 |
| YU45988B (sh) | 1992-12-21 |
| AU4959485A (en) | 1986-04-08 |
| YU143985A (en) | 1987-10-31 |
| ES547707A0 (es) | 1987-01-16 |
| IT1178511B (it) | 1987-09-09 |
| NO171887B (no) | 1993-02-08 |
| ATE61733T1 (de) | 1991-04-15 |
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