JPH0410458B2 - - Google Patents

Info

Publication number
JPH0410458B2
JPH0410458B2 JP58181088A JP18108883A JPH0410458B2 JP H0410458 B2 JPH0410458 B2 JP H0410458B2 JP 58181088 A JP58181088 A JP 58181088A JP 18108883 A JP18108883 A JP 18108883A JP H0410458 B2 JPH0410458 B2 JP H0410458B2
Authority
JP
Japan
Prior art keywords
phenyl group
cells
group
day
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58181088A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59134745A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP58181088A priority Critical patent/JPS59134745A/ja
Priority to US06/620,473 priority patent/US4656192A/en
Publication of JPS59134745A publication Critical patent/JPS59134745A/ja
Publication of JPH0410458B2 publication Critical patent/JPH0410458B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP58181088A 1983-09-28 1983-09-28 抗腫瘍作用を有するトロポロン誘導体 Granted JPS59134745A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP58181088A JPS59134745A (ja) 1983-09-28 1983-09-28 抗腫瘍作用を有するトロポロン誘導体
US06/620,473 US4656192A (en) 1983-09-28 1984-06-14 Tropolone derivatives, processes for the preparation thereof and the use thereof as anti-tumor agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58181088A JPS59134745A (ja) 1983-09-28 1983-09-28 抗腫瘍作用を有するトロポロン誘導体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP813483A Division JPS59134720A (ja) 1983-01-20 1983-01-20 抗腫瘍薬

Publications (2)

Publication Number Publication Date
JPS59134745A JPS59134745A (ja) 1984-08-02
JPH0410458B2 true JPH0410458B2 (fr) 1992-02-25

Family

ID=16094607

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58181088A Granted JPS59134745A (ja) 1983-09-28 1983-09-28 抗腫瘍作用を有するトロポロン誘導体

Country Status (2)

Country Link
US (1) US4656192A (fr)
JP (1) JPS59134745A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4666395B2 (ja) * 2007-08-10 2011-04-06 ローム株式会社 樹脂パッケージ型半導体装置の製造方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61215341A (ja) * 1985-03-20 1986-09-25 Masatoshi Yamato 抗腫瘍活性トロポロン誘導体の製法
US5284866A (en) * 1992-10-05 1994-02-08 Bristol-Myers Squibb Company 1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyrans useful as antitumor agents
DE19537365C1 (de) * 1995-10-06 1996-12-19 Fraunhofer Ges Forschung Verfahren zur Stabilisierung der Schmelzeviskosität von Zinn-, Titan- und/oder Zirkoniumverbindungen als Katalysator und/oder Initiator enthaltender aliphatischer oder aromatisch-aliphatischer Homo- oder Copolyester und Verwendung einer Verbindung, die mindestens einen Tropolonring aufweist als Maskierungsmittel in Polyesterschmelzen
JP4018816B2 (ja) * 1998-09-08 2007-12-05 壽製薬株式会社 シクロヘプテノン誘導体及びその製造方法並びにそれを利用してシクロヘプトイミダゾール誘導体を製造する方法
US6787675B2 (en) * 2002-07-29 2004-09-07 Warner-Lambert Company Substituted tropolone compounds, oral care compositions containing the same and methods of using the same
US6689342B1 (en) * 2002-07-29 2004-02-10 Warner-Lambert Company Oral care compositions comprising tropolone compounds and essential oils and methods of using the same
MXPA05001182A (es) * 2002-07-29 2005-05-16 Warner Lambert Co Composiciones para la higiene bucal que comprenden compuestos de tropolona y aceites esenciales y metodos para utilizar las mismas.
US20070116664A1 (en) * 2005-11-21 2007-05-24 Shmuel Gonen Methods and compositions for treating hair and skin afflictions
US7540906B2 (en) * 2005-12-30 2009-06-02 E.I. Du Pont De Nemours & Company Metal salts of hydrolyzed olefin/maleic anhydride copolymers and their use as wood preservatives
US7427316B2 (en) * 2005-12-30 2008-09-23 E.I. Du Pont De Nemours And Company Tropolone complexes as wood preservatives
US7462227B2 (en) * 2005-12-30 2008-12-09 E.I. Du Pont De Nemours And Company Ibuprofen complexes as wood preservatives
US7497901B2 (en) * 2005-12-30 2009-03-03 E. I. Dupont De Nemours And Company Tungstate and molybate wood preservatives
CN109776357A (zh) * 2018-08-29 2019-05-21 湖北工业大学 一种含环庚三烯酚酮小分子抑制剂及在抑制鸟氨酸脱羧酶（odc）上的应用
CN110330533B (zh) * 2019-07-26 2021-05-28 广西师范大学 2-甲基-8-羟基喹啉与托酚酮混配铂配合物及其制备方法和应用
CN110256504B (zh) * 2019-07-26 2021-05-18 广西师范大学 环庚三烯酚酮与8-羟基喹啉混配铂配合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5917097B2 (ja) * 1977-09-02 1984-04-19 恭光 田村 トロポロン誘導体の製造方法
JPS5461158A (en) * 1977-10-20 1979-05-17 Idemitsu Kosan Co Ltd 4-1-acetamido-3-(dichlorophenyl) propyl tropolones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4666395B2 (ja) * 2007-08-10 2011-04-06 ローム株式会社 樹脂パッケージ型半導体装置の製造方法

Also Published As

Publication number Publication date
US4656192A (en) 1987-04-07
JPS59134745A (ja) 1984-08-02

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