JPH0368010B2 - - Google Patents
Info
- Publication number
- JPH0368010B2 JPH0368010B2 JP59184931A JP18493184A JPH0368010B2 JP H0368010 B2 JPH0368010 B2 JP H0368010B2 JP 59184931 A JP59184931 A JP 59184931A JP 18493184 A JP18493184 A JP 18493184A JP H0368010 B2 JPH0368010 B2 JP H0368010B2
- Authority
- JP
- Japan
- Prior art keywords
- lactose
- laxative
- lactic acid
- particle size
- acid bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 78
- 239000008101 lactose Substances 0.000 claims description 75
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 56
- 239000008141 laxative Substances 0.000 claims description 44
- 241000894006 Bacteria Species 0.000 claims description 34
- 230000002475 laxative effect Effects 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 239000004310 lactic acid Substances 0.000 claims description 28
- 235000014655 lactic acid Nutrition 0.000 claims description 28
- 239000002245 particle Substances 0.000 claims description 25
- 241000233866 Fungi Species 0.000 claims description 18
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 11
- 239000002075 main ingredient Substances 0.000 claims description 9
- 235000016709 nutrition Nutrition 0.000 claims description 8
- 230000000694 effects Effects 0.000 description 22
- 210000000936 intestine Anatomy 0.000 description 19
- 102000004190 Enzymes Human genes 0.000 description 17
- 108090000790 Enzymes Proteins 0.000 description 17
- 239000000243 solution Substances 0.000 description 17
- 239000000843 powder Substances 0.000 description 16
- 210000002784 stomach Anatomy 0.000 description 15
- 239000004615 ingredient Substances 0.000 description 14
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 13
- 235000010413 sodium alginate Nutrition 0.000 description 13
- 229940005550 sodium alginate Drugs 0.000 description 13
- 239000000661 sodium alginate Substances 0.000 description 13
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 12
- 229940125722 laxative agent Drugs 0.000 description 12
- 229940079593 drug Drugs 0.000 description 10
- 239000003814 drug Substances 0.000 description 10
- 239000000654 additive Substances 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 230000000996 additive effect Effects 0.000 description 7
- 235000021329 brown rice Nutrition 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- 239000001569 carbon dioxide Substances 0.000 description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 description 6
- 238000000855 fermentation Methods 0.000 description 6
- 230000004151 fermentation Effects 0.000 description 6
- 230000000968 intestinal effect Effects 0.000 description 6
- 239000000725 suspension Substances 0.000 description 6
- 206010010774 Constipation Diseases 0.000 description 5
- 206010047700 Vomiting Diseases 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- 238000011282 treatment Methods 0.000 description 5
- 206010056325 Faecaloma Diseases 0.000 description 4
- 208000008415 Fecal Impaction Diseases 0.000 description 4
- 238000000354 decomposition reaction Methods 0.000 description 4
- 230000013872 defecation Effects 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 206010000060 Abdominal distension Diseases 0.000 description 3
- 241000186660 Lactobacillus Species 0.000 description 3
- 208000024330 bloating Diseases 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 229940039696 lactobacillus Drugs 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000001575 pathological effect Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 206010028813 Nausea Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 150000002597 lactoses Chemical class 0.000 description 2
- 235000013557 nattō Nutrition 0.000 description 2
- 230000008693 nausea Effects 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 235000012905 Brassica oleracea var viridis Nutrition 0.000 description 1
- 241000195649 Chlorella <Chlorellales> Species 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010015995 Eyelid ptosis Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- 229920002581 Glucomannan Polymers 0.000 description 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000021152 breakfast Nutrition 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 231100000749 chronicity Toxicity 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011362 coarse particle Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 229940046240 glucomannan Drugs 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 201000003004 ptosis Diseases 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59184931A JPS6163618A (ja) | 1984-09-03 | 1984-09-03 | 下剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59184931A JPS6163618A (ja) | 1984-09-03 | 1984-09-03 | 下剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6163618A JPS6163618A (ja) | 1986-04-01 |
| JPH0368010B2 true JPH0368010B2 (de) | 1991-10-25 |
Family
ID=16161848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59184931A Granted JPS6163618A (ja) | 1984-09-03 | 1984-09-03 | 下剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6163618A (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0774158B2 (ja) * | 1986-09-03 | 1995-08-09 | 東亜薬品工業株式会社 | ３種菌共生混合物 |
| US7029702B2 (en) * | 1998-07-07 | 2006-04-18 | Ritter Natural Sciences Llc | Method for increasing lactose tolerance in mammals exhibiting lactose intolerance |
| WO2006012536A2 (en) | 2004-07-22 | 2006-02-02 | Ritter Andrew J | Methods and compositions for treating lactose intolerance |
| SG2014014435A (en) | 2009-02-24 | 2014-07-30 | Ritter Pharmaceuticals Inc | Prebiotic formulations and methods of use |
| US8785160B2 (en) | 2009-02-24 | 2014-07-22 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS555490A (en) * | 1978-05-30 | 1980-01-16 | Gen Electric | Cooling system for gas turbine |
| JPS588018A (ja) * | 1981-07-07 | 1983-01-18 | Akira Yamauchi | 下剤 |
-
1984
- 1984-09-03 JP JP59184931A patent/JPS6163618A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS555490A (en) * | 1978-05-30 | 1980-01-16 | Gen Electric | Cooling system for gas turbine |
| JPS588018A (ja) * | 1981-07-07 | 1983-01-18 | Akira Yamauchi | 下剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6163618A (ja) | 1986-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |