JPH0354089B2 - - Google Patents
Info
- Publication number
- JPH0354089B2 JPH0354089B2 JP57083370A JP8337082A JPH0354089B2 JP H0354089 B2 JPH0354089 B2 JP H0354089B2 JP 57083370 A JP57083370 A JP 57083370A JP 8337082 A JP8337082 A JP 8337082A JP H0354089 B2 JPH0354089 B2 JP H0354089B2
- Authority
- JP
- Japan
- Prior art keywords
- withdrawal
- treatment
- symptoms
- drug according
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH330681 | 1981-05-21 | ||
CH3306/81-7 | 1981-05-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5823630A JPS5823630A (ja) | 1983-02-12 |
JPH0354089B2 true JPH0354089B2 (en, 2012) | 1991-08-19 |
Family
ID=4253131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57083370A Granted JPS5823630A (ja) | 1981-05-21 | 1982-05-19 | 薬剤禁断症状の処置剤 |
Country Status (11)
Country | Link |
---|---|
US (2) | US4444758A (en, 2012) |
EP (1) | EP0065747B1 (en, 2012) |
JP (1) | JPS5823630A (en, 2012) |
AU (1) | AU552547B2 (en, 2012) |
CA (1) | CA1188989A (en, 2012) |
DE (1) | DE3218761A1 (en, 2012) |
IE (1) | IE53395B1 (en, 2012) |
IL (1) | IL65782A (en, 2012) |
IT (1) | IT1152116B (en, 2012) |
PH (1) | PH17981A (en, 2012) |
ZA (1) | ZA823369B (en, 2012) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5486599A (en) * | 1989-03-29 | 1996-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Construction and use of synthetic constructs encoding syndecan |
US5486362A (en) * | 1991-05-07 | 1996-01-23 | Dynagen, Inc. | Controlled, sustained release delivery system for treating drug dependency |
US5403595A (en) * | 1991-05-07 | 1995-04-04 | Dynagen, Inc. | Controlled, sustained release delivery system for smoking cessation |
US5780051A (en) * | 1992-04-02 | 1998-07-14 | Dynagen, Inc. | Methods and articles of manufacture for nicotine cessation and monitoring nicotine use |
US7220737B1 (en) | 1997-09-04 | 2007-05-22 | Novoneuron, Inc | Noribogaine in the treatment of pain and drug addiction |
ES2395268T3 (es) * | 1997-09-04 | 2013-02-11 | Demerx, Inc. | Noribogaína para el tratamiento del dolor y la drogadicción |
CA2360124A1 (en) * | 1999-02-05 | 2000-08-10 | The Victoria University Of Manchester | Regulation of anaesthesia |
DE10014007A1 (de) * | 2000-03-22 | 2001-10-11 | Strathmann Ag & Co | Neue Darreichungsformen für DSIP |
RU2005128993A (ru) * | 2005-09-08 | 2007-03-20 | Общество С Ограниченной Ответственностью Исследовательский Центр "Комкон" (Ru) | Средство для коррекции стресс-индуцируемых нейромедиаторных, нейроэндокринных и метаболических нарушений, а также способ профилактики и лечения сопутствующих им паталогических состояний |
EP2205266A2 (en) * | 2007-09-11 | 2010-07-14 | Mondobiotech Laboratories AG | Use of the peptide combination thymosin beta 4 and delta sleep inducing peptide as a therapeutic agent |
US8765737B1 (en) | 2010-05-11 | 2014-07-01 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US8362007B1 (en) | 2010-05-11 | 2013-01-29 | Demerx, Inc. | Substituted noribogaine |
US9394294B2 (en) | 2010-05-11 | 2016-07-19 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US8637648B1 (en) | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
US8802832B2 (en) | 2010-06-22 | 2014-08-12 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
US9586954B2 (en) | 2010-06-22 | 2017-03-07 | Demerx, Inc. | N-substituted noribogaine prodrugs |
US8741891B1 (en) | 2010-06-22 | 2014-06-03 | Demerx, Inc. | N-substituted noribogaine prodrugs |
EP2595632A1 (en) | 2010-07-23 | 2013-05-29 | DemeRx, Inc. | Noribogaine compositions |
EP2481740B1 (en) | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
US9617274B1 (en) | 2011-08-26 | 2017-04-11 | Demerx, Inc. | Synthetic noribogaine |
WO2013085922A1 (en) | 2011-12-09 | 2013-06-13 | Demerx, Inc. | Phosphate esters of noribogaine |
US9150584B2 (en) | 2012-01-25 | 2015-10-06 | Demerx, Inc. | Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them |
EP2807168A4 (en) | 2012-01-25 | 2015-10-14 | Demerx Inc | SYNTHETIC VOACANGINE |
US9045481B2 (en) | 2012-12-20 | 2015-06-02 | Demerx, Inc. | Substituted noribogaine |
US8940728B2 (en) | 2012-12-20 | 2015-01-27 | Demerx, Inc. | Substituted noribogaine |
JP2016508979A (ja) | 2012-12-20 | 2016-03-24 | デメレックス, インコーポレイテッド | 置換ノルイボガイン |
US9550789B2 (en) | 2014-06-18 | 2017-01-24 | Demerx, Inc. | Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH634331A5 (de) * | 1977-06-30 | 1983-01-31 | Hoffmann La Roche | Phosphorylierte nonapeptide und verfahren zu deren herstellung. |
-
1982
- 1982-04-21 CA CA000401386A patent/CA1188989A/en not_active Expired
- 1982-05-04 IT IT21072/82A patent/IT1152116B/it active
- 1982-05-14 ZA ZA823369A patent/ZA823369B/xx unknown
- 1982-05-14 PH PH27299A patent/PH17981A/en unknown
- 1982-05-14 IL IL65782A patent/IL65782A/xx not_active IP Right Cessation
- 1982-05-17 AU AU83756/82A patent/AU552547B2/en not_active Expired
- 1982-05-17 US US06/379,162 patent/US4444758A/en not_active Expired - Lifetime
- 1982-05-18 EP EP82104367A patent/EP0065747B1/de not_active Expired
- 1982-05-18 DE DE3218761A patent/DE3218761A1/de active Granted
- 1982-05-19 JP JP57083370A patent/JPS5823630A/ja active Granted
- 1982-05-20 IE IE1214/82A patent/IE53395B1/en not_active IP Right Cessation
-
1984
- 1984-02-24 US US06/583,520 patent/US4496545A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ZA823369B (en) | 1983-03-30 |
IE821214L (en) | 1982-11-21 |
DE3218761C2 (en, 2012) | 1993-05-06 |
IL65782A0 (en) | 1982-08-31 |
AU8375682A (en) | 1982-11-25 |
EP0065747B1 (de) | 1986-10-15 |
IT8221072A0 (it) | 1982-05-04 |
IE53395B1 (en) | 1988-11-09 |
US4444758A (en) | 1984-04-24 |
PH17981A (en) | 1985-02-26 |
AU552547B2 (en) | 1986-06-05 |
EP0065747A1 (de) | 1982-12-01 |
DE3218761A1 (de) | 1982-12-16 |
US4496545A (en) | 1985-01-29 |
IT1152116B (it) | 1986-12-31 |
CA1188989A (en) | 1985-06-18 |
JPS5823630A (ja) | 1983-02-12 |
IL65782A (en) | 1985-08-30 |
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