JPH033640B2 - - Google Patents

Info

Publication number
JPH033640B2
JPH033640B2 JP60243149A JP24314985A JPH033640B2 JP H033640 B2 JPH033640 B2 JP H033640B2 JP 60243149 A JP60243149 A JP 60243149A JP 24314985 A JP24314985 A JP 24314985A JP H033640 B2 JPH033640 B2 JP H033640B2
Authority
JP
Japan
Prior art keywords
crystal production
crystal
box
section
path switching
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60243149A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62106000A (ja
Inventor
Shozo Fujita
Hachiro Yasuda
Akio Sugama
Naomi Nakane
Akio Yagishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujitsu Ltd
Original Assignee
Fujitsu Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujitsu Ltd filed Critical Fujitsu Ltd
Priority to JP60243149A priority Critical patent/JPS62106000A/ja
Priority to US06/924,330 priority patent/US4755363A/en
Priority to DE8686308404T priority patent/DE3684762D1/de
Priority to EP86308404A priority patent/EP0225050B1/en
Publication of JPS62106000A publication Critical patent/JPS62106000A/ja
Publication of JPH033640B2 publication Critical patent/JPH033640B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C30CRYSTAL GROWTH
    • C30BSINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • CCHEMISTRY; METALLURGY
    • C30CRYSTAL GROWTH
    • C30BSINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54Organic compounds
    • C30B29/58Macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00389Feeding through valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00389Feeding through valves
    • B01J2219/00391Rotary valves
    • B01J2219/00394Rotary valves in multiple arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00495Means for heating or cooling the reaction vessels
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S117/00Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10S117/901Levitation, reduced gravity, microgravity, space
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10Apparatus
    • Y10T117/1004Apparatus with means for measuring, testing, or sensing
    • Y10T117/1008Apparatus with means for measuring, testing, or sensing with responsive control means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10Apparatus
    • Y10T117/1024Apparatus for crystallization from liquid or supercritical state

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
JP60243149A 1985-10-30 1985-10-30 生体高分子結晶自動作製装置 Granted JPS62106000A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP60243149A JPS62106000A (ja) 1985-10-30 1985-10-30 生体高分子結晶自動作製装置
US06/924,330 US4755363A (en) 1985-10-30 1986-10-29 Automated biopolymer crystal preparation apparatus
DE8686308404T DE3684762D1 (de) 1985-10-30 1986-10-29 Vorrichtung und verfahren zur automatischen herstellung von bipolymer-kristallen.
EP86308404A EP0225050B1 (en) 1985-10-30 1986-10-29 Automated biopolymer crystal preparation apparatus and process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60243149A JPS62106000A (ja) 1985-10-30 1985-10-30 生体高分子結晶自動作製装置

Publications (2)

Publication Number Publication Date
JPS62106000A JPS62106000A (ja) 1987-05-16
JPH033640B2 true JPH033640B2 (enExample) 1991-01-21

Family

ID=17099520

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60243149A Granted JPS62106000A (ja) 1985-10-30 1985-10-30 生体高分子結晶自動作製装置

Country Status (4)

Country Link
US (1) US4755363A (enExample)
EP (1) EP0225050B1 (enExample)
JP (1) JPS62106000A (enExample)
DE (1) DE3684762D1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2604917B1 (fr) * 1986-10-09 1989-01-27 Aerospatiale Procede, cellule et dispositif de cristallogenese, notamment par vaisseau spatial
DE3738840A1 (de) * 1987-08-12 1989-02-23 Intospace Gmbh Kristallisationseinrichtung
DE3882011T2 (de) * 1987-10-27 1993-09-30 Fujitsu Ltd Verfahren und Vorrichtung zur Herstellung von Biopolymer-Einkristall.
US4919899A (en) * 1988-02-29 1990-04-24 Herrmann Frederick T Crystal growth apparatus
US4886646A (en) * 1988-03-23 1989-12-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hanging drop crystal growth apparatus and method
JP2740375B2 (ja) * 1990-10-25 1998-04-15 富士通株式会社 生体高分子結晶化装置
JP2914758B2 (ja) * 1990-12-18 1999-07-05 富士通株式会社 タンパク質溶液濃度の2次元測定方法および装置
US6027565A (en) * 1991-02-25 2000-02-22 Bugg; Charles E. Method and apparatus for crystalizing macromolecules in microgravity
US5866114A (en) * 1992-06-09 1999-02-02 Chiron Corporation Crystallization of M-CSFα
US5985356A (en) * 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
US6406903B2 (en) * 1995-09-25 2002-06-18 University Of Alabama At Birmingham Dynamically controlled crystal growth system
FR2770231A1 (fr) * 1997-10-24 1999-04-30 Commissariat Energie Atomique Dispositif et procede d'elaboration de cristaux par sustentation sur film de gaz
EA200000672A1 (ru) * 1997-12-18 2000-12-25 Эли Лилли Энд Компани Кристалический терипаратид
WO1999042191A1 (en) * 1998-02-18 1999-08-26 Biospace International Inc. Dynamically controlled crystallization method and apparatus and crystals obtained thereby
US5961934A (en) * 1998-02-18 1999-10-05 Biospace International Inc. Dynamically controlled crystallization method and apparatus and crystals obtained thereby
US20040064105A1 (en) * 2002-09-27 2004-04-01 Capes David Francis Single-use syringe
US7798993B2 (en) * 1998-07-29 2010-09-21 Becton, Dickinson And Company Single use syringe
US7250305B2 (en) * 2001-07-30 2007-07-31 Uab Research Foundation Use of dye to distinguish salt and protein crystals under microcrystallization conditions
US7244396B2 (en) * 1999-04-06 2007-07-17 Uab Research Foundation Method for preparation of microarrays for screening of crystal growth conditions
US20020164812A1 (en) * 1999-04-06 2002-11-07 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
US7247490B2 (en) * 1999-04-06 2007-07-24 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
WO2000060345A1 (en) * 1999-04-06 2000-10-12 University Of Alabama At Birmingham Research Foundation Method for screening crystallization conditions in solution crystal growth
US7214540B2 (en) * 1999-04-06 2007-05-08 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
US6296673B1 (en) 1999-06-18 2001-10-02 The Regents Of The University Of California Methods and apparatus for performing array microcrystallizations
US6630006B2 (en) * 1999-06-18 2003-10-07 The Regents Of The University Of California Method for screening microcrystallizations for crystal formation
US6818060B2 (en) * 1999-08-02 2004-11-16 Emerald Biostructures, Inc. Robot for mixing crystallization trial matrices
US20020169512A1 (en) * 1999-08-02 2002-11-14 Decode Genetics Ehf. Plate mover for crystallization data collection
CA2424033A1 (en) * 2000-09-28 2002-04-04 Bsi Proteomics Corporation Automated robotic device for dynamically controlled crystallization of proteins
US6402837B1 (en) 2000-10-30 2002-06-11 Abraham Shtrahman Apparatus and method of preparation for automated high output biopolymer crystallization via vapor diffusion sitting drop and micro-batch techniques
US7670429B2 (en) * 2001-04-05 2010-03-02 The California Institute Of Technology High throughput screening of crystallization of materials
US20030119060A1 (en) * 2001-08-10 2003-06-26 Desrosiers Peter J. Apparatuses and methods for creating and testing pre-formulations and systems for same
JP3759891B2 (ja) * 2001-09-27 2006-03-29 独立行政法人理化学研究所 タンパク質の結晶化方法及び装置
US20040033166A1 (en) * 2001-09-28 2004-02-19 Leonard Arnowitz Automated robotic device for dynamically controlled crystallization of proteins
US20070026528A1 (en) * 2002-05-30 2007-02-01 Delucas Lawrence J Method for screening crystallization conditions in solution crystal growth
US20040007672A1 (en) * 2002-07-10 2004-01-15 Delucas Lawrence J. Method for distinguishing between biomolecule and non-biomolecule crystals
US7118626B2 (en) * 2003-08-29 2006-10-10 University Of Alabama In Huntsville Crystallization cassette for the growth and analysis of macromolecular crystals and an associated method
US7182810B2 (en) * 2004-04-16 2007-02-27 Canadian Space Agency Protein temperature evaporation-controlled crystallization device and method thereof
US7507552B1 (en) 2004-04-16 2009-03-24 Takeda San Diego, Inc. Crystallization of histone deacetylase 2
JP4875591B2 (ja) * 2007-11-06 2012-02-15 古河機械金属株式会社 結晶観察装置
AU2009273998A1 (en) * 2008-07-23 2010-01-28 Ancora Pharmaceuticals Inc. Automated oligosaccharide synthesizer
CN104722342B (zh) 2009-03-24 2017-01-11 芝加哥大学 滑动式芯片装置和方法
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
JP2012076963A (ja) * 2010-10-01 2012-04-19 Kiyohara Optics Inc 強磁場中結晶生成装置
JP5657326B2 (ja) * 2010-10-01 2015-01-21 株式会社 清原光学 強磁場中顕微鏡観察装置
JP2013066404A (ja) * 2011-09-21 2013-04-18 Kiyohara Optics Inc 結晶化プレートの観察装置
JP2013067528A (ja) * 2011-09-21 2013-04-18 Kiyohara Optics Inc 結晶化プレートの観察装置
JP5896550B2 (ja) * 2011-09-21 2016-03-30 株式会社 清原光学 結晶化プレート

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4263010A (en) * 1979-10-31 1981-04-21 University Patents, Inc. Control method and apparatus for crystallizer process control
US4332590A (en) * 1981-02-20 1982-06-01 Phillips Petroleum Company Reactor control

Also Published As

Publication number Publication date
JPS62106000A (ja) 1987-05-16
EP0225050A2 (en) 1987-06-10
US4755363A (en) 1988-07-05
DE3684762D1 (de) 1992-05-14
EP0225050A3 (en) 1988-04-27
EP0225050B1 (en) 1992-04-08

Similar Documents

Publication Publication Date Title
JPH033640B2 (enExample)
Krauss et al. An overview of biological macromolecule crystallization
DE69033032T2 (de) Integriertes zellkultur-proteinreinigungssystem zur automatisierten herstellung und reinigung von zellkulturprodukten
US20220325708A1 (en) Alternating tangential flow rapid harvesting
US5221410A (en) Crystal forming device
Bergfors Protein crystallization
TWI656839B (zh) 高密度細胞儲存方法
McPherson Two approaches to the rapid screening of crystallization conditions
EP0553539A1 (en) Crystal forming device and automated crystallization system
DE3504715C2 (enExample)
Baldock et al. A comparison of microbatch and vapour diffusion for initial screening of crystallization conditions
JP2006513170A (ja) 酸および塩基から溶液を連続的に自動混合する方法
JPS61257181A (ja) 動物細胞の培養装置
US5043431A (en) Method and apparatus for the production of TGF-β
McPherson Useful principles for the crystallization of proteins
Adawy et al. High resolution protein crystals using an efficient convection-free geometry
Giegé et al. Crystallogenesis of proteins
GB2249492A (en) Crystallisation method and apparatus
JPS60259179A (ja) 細胞培養槽及び細胞培養方法
Ishchenko et al. Lipidic cubic phase technologies for structural studies of membrane proteins
JPH03172170A (ja) 細胞の培養方法及び装置
EP0242984B1 (en) Culture device
CN101522277B (zh) 用于生物大分子结晶的结晶装置和方法及其应用
JPH04358527A (ja) 微量溶液の透析方法および装置
Giegé et al. General methods