DE3684762D1 - Vorrichtung und verfahren zur automatischen herstellung von bipolymer-kristallen. - Google Patents

Vorrichtung und verfahren zur automatischen herstellung von bipolymer-kristallen.

Info

Publication number
DE3684762D1
DE3684762D1 DE8686308404T DE3684762T DE3684762D1 DE 3684762 D1 DE3684762 D1 DE 3684762D1 DE 8686308404 T DE8686308404 T DE 8686308404T DE 3684762 T DE3684762 T DE 3684762T DE 3684762 D1 DE3684762 D1 DE 3684762D1
Authority
DE
Germany
Prior art keywords
bipolymer
crystals
automatic production
automatic
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686308404T
Other languages
German (de)
English (en)
Inventor
Shozo Fujita
Hachiro Yasuda
Akio Sugama
Naomi Nakane
Teruo Yagishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujitsu Ltd
Original Assignee
Fujitsu Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujitsu Ltd filed Critical Fujitsu Ltd
Application granted granted Critical
Publication of DE3684762D1 publication Critical patent/DE3684762D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C30B29/58—Macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00389—Feeding through valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00389—Feeding through valves
    • B01J2219/00391—Rotary valves
    • B01J2219/00394—Rotary valves in multiple arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S117/00—Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10S117/901—Levitation, reduced gravity, microgravity, space
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00—Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10—Apparatus
    • Y10T117/1004—Apparatus with means for measuring, testing, or sensing
    • Y10T117/1008—Apparatus with means for measuring, testing, or sensing with responsive control means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00—Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10—Apparatus
    • Y10T117/1024—Apparatus for crystallization from liquid or supercritical state

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
DE8686308404T 1985-10-30 1986-10-29 Vorrichtung und verfahren zur automatischen herstellung von bipolymer-kristallen. Expired - Lifetime DE3684762D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60243149A JPS62106000A (ja) 1985-10-30 1985-10-30 生体高分子結晶自動作製装置

Publications (1)

Publication Number Publication Date
DE3684762D1 true DE3684762D1 (de) 1992-05-14

Family

ID=17099520

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686308404T Expired - Lifetime DE3684762D1 (de) 1985-10-30 1986-10-29 Vorrichtung und verfahren zur automatischen herstellung von bipolymer-kristallen.

Country Status (4)

Country Link
US (1) US4755363A (enExample)
EP (1) EP0225050B1 (enExample)
JP (1) JPS62106000A (enExample)
DE (1) DE3684762D1 (enExample)

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FR2604917B1 (fr) * 1986-10-09 1989-01-27 Aerospatiale Procede, cellule et dispositif de cristallogenese, notamment par vaisseau spatial
DE3738840A1 (de) * 1987-08-12 1989-02-23 Intospace Gmbh Kristallisationseinrichtung
US4990216A (en) * 1987-10-27 1991-02-05 Fujitsu Limited Process and apparatus for preparation of single crystal of biopolymer
US4919899A (en) * 1988-02-29 1990-04-24 Herrmann Frederick T Crystal growth apparatus
US4886646A (en) * 1988-03-23 1989-12-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hanging drop crystal growth apparatus and method
JP2740375B2 (ja) * 1990-10-25 1998-04-15 富士通株式会社 生体高分子結晶化装置
JP2914758B2 (ja) * 1990-12-18 1999-07-05 富士通株式会社 タンパク質溶液濃度の２次元測定方法および装置
US6027565A (en) * 1991-02-25 2000-02-22 Bugg; Charles E. Method and apparatus for crystalizing macromolecules in microgravity
US5866114A (en) * 1992-06-09 1999-02-02 Chiron Corporation Crystallization of M-CSFα
US5985356A (en) * 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
US6406903B2 (en) * 1995-09-25 2002-06-18 University Of Alabama At Birmingham Dynamically controlled crystal growth system
FR2770231A1 (fr) * 1997-10-24 1999-04-30 Commissariat Energie Atomique Dispositif et procede d'elaboration de cristaux par sustentation sur film de gaz
CN1281467A (zh) * 1997-12-18 2001-01-24 伊莱利利公司 结晶特立帕肽
US5961934A (en) 1998-02-18 1999-10-05 Biospace International Inc. Dynamically controlled crystallization method and apparatus and crystals obtained thereby
WO1999042191A1 (en) * 1998-02-18 1999-08-26 Biospace International Inc. Dynamically controlled crystallization method and apparatus and crystals obtained thereby
US7798993B2 (en) * 1998-07-29 2010-09-21 Becton, Dickinson And Company Single use syringe
US20040064105A1 (en) * 2002-09-27 2004-04-01 Capes David Francis Single-use syringe
US7247490B2 (en) * 1999-04-06 2007-07-24 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
US7250305B2 (en) * 2001-07-30 2007-07-31 Uab Research Foundation Use of dye to distinguish salt and protein crystals under microcrystallization conditions
US7244396B2 (en) * 1999-04-06 2007-07-17 Uab Research Foundation Method for preparation of microarrays for screening of crystal growth conditions
US20020164812A1 (en) * 1999-04-06 2002-11-07 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
US7214540B2 (en) * 1999-04-06 2007-05-08 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
EP1181548B1 (en) * 1999-04-06 2007-03-21 The University of Alabama at Birmingham Research Foundation Method for screening crystallization conditions in solution crystal growth
US6630006B2 (en) * 1999-06-18 2003-10-07 The Regents Of The University Of California Method for screening microcrystallizations for crystal formation
US6296673B1 (en) 1999-06-18 2001-10-02 The Regents Of The University Of California Methods and apparatus for performing array microcrystallizations
US6818060B2 (en) * 1999-08-02 2004-11-16 Emerald Biostructures, Inc. Robot for mixing crystallization trial matrices
US20020169512A1 (en) * 1999-08-02 2002-11-14 Decode Genetics Ehf. Plate mover for crystallization data collection
GB2384729A (en) * 2000-09-28 2003-08-06 Bsi Proteomics Corp Automated robotic device for dynamically controlled crystallization of proteins
US6402837B1 (en) * 2000-10-30 2002-06-11 Abraham Shtrahman Apparatus and method of preparation for automated high output biopolymer crystallization via vapor diffusion sitting drop and micro-batch techniques
US7670429B2 (en) * 2001-04-05 2010-03-02 The California Institute Of Technology High throughput screening of crystallization of materials
US20030119060A1 (en) * 2001-08-10 2003-06-26 Desrosiers Peter J. Apparatuses and methods for creating and testing pre-formulations and systems for same
JP3759891B2 (ja) * 2001-09-27 2006-03-29 独立行政法人理化学研究所 タンパク質の結晶化方法及び装置
US20040033166A1 (en) * 2001-09-28 2004-02-19 Leonard Arnowitz Automated robotic device for dynamically controlled crystallization of proteins
US20070026528A1 (en) * 2002-05-30 2007-02-01 Delucas Lawrence J Method for screening crystallization conditions in solution crystal growth
AU2003256469A1 (en) * 2002-07-10 2004-01-23 Uab Research Foundation Method for distinguishing between biomolecule and non-biomolecule crystals
US7118626B2 (en) * 2003-08-29 2006-10-10 University Of Alabama In Huntsville Crystallization cassette for the growth and analysis of macromolecular crystals and an associated method
US7507552B1 (en) 2004-04-16 2009-03-24 Takeda San Diego, Inc. Crystallization of histone deacetylase 2
US7182810B2 (en) * 2004-04-16 2007-02-27 Canadian Space Agency Protein temperature evaporation-controlled crystallization device and method thereof
JP4875591B2 (ja) * 2007-11-06 2012-02-15 古河機械金属株式会社 結晶観察装置
WO2010011828A1 (en) * 2008-07-23 2010-01-28 Ancora Pharmaceuticals Inc. Automated oligosaccharide synthesizer
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
CN104722342B (zh) 2009-03-24 2017-01-11 芝加哥大学 滑动式芯片装置和方法
JP5657326B2 (ja) * 2010-10-01 2015-01-21 株式会社 清原光学 強磁場中顕微鏡観察装置
JP2012076963A (ja) * 2010-10-01 2012-04-19 Kiyohara Optics Inc 強磁場中結晶生成装置
JP2013067528A (ja) * 2011-09-21 2013-04-18 Kiyohara Optics Inc 結晶化プレートの観察装置
JP2013066404A (ja) * 2011-09-21 2013-04-18 Kiyohara Optics Inc 結晶化プレートの観察装置
JP5896550B2 (ja) * 2011-09-21 2016-03-30 株式会社 清原光学 結晶化プレート

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US4263010A (en) * 1979-10-31 1981-04-21 University Patents, Inc. Control method and apparatus for crystallizer process control
US4332590A (en) * 1981-02-20 1982-06-01 Phillips Petroleum Company Reactor control

Also Published As

Publication number Publication date
US4755363A (en) 1988-07-05
EP0225050A3 (en) 1988-04-27
EP0225050B1 (en) 1992-04-08
JPS62106000A (ja) 1987-05-16
EP0225050A2 (en) 1987-06-10
JPH033640B2 (enExample) 1991-01-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee