JPH02211848A - Functional food containing protein polysaccharide component of agaricus blazei - Google Patents

Abstract

PURPOSE:To obtain the subject food having antitumor activity and useful as a health drink, etc., by cutting the fruit body or dried fruit body of Agaricus blazei into small pieces or pulverizing the fruit body, etc. CONSTITUTION:The fruit body or dried fruit body of Agaricus blazei (FERM 4731) is cut into small pieces or pulverized to obtain the objective food. Preferably, the fruit body or dried fruit body is extracted with an aqueous solvent and the obtained liquid is added to a food-processing raw material optionally after concentration.

Description

DETAILED DESCRIPTION OF THE INVENTION (1) Object of the Invention The present invention relates to a food containing a protein polysaccharide component contained in Kawariharatake (commonly known as Himematsutake). For details, see Agaricus blazei Murrill, a member of the Agaricaceae family, which was successfully cultivated by one of the present inventors (Patent No. 1207227. Name of the invention: Purpose of utilizing protein polysaccharides with remarkable antitumor activity contained in a method for cultivating mushrooms of the Agaricaceae family). The present invention relates to a functional food in which the fruiting body or a dried product of the fruiting body is added as it is or in powdered form, or a liquid extracted indirectly with an aqueous solvent is used.

The present invention is disclosed in Japanese Patent No. 1207227 by the present inventor.
"Cultivation method for mushrooms of the genus Agaricus", Patent Tube 144264
No. 7 F method for producing protein polysaccharide having antitumor activity),
This patent relates to inventions utilizing patent No. 1442648, ``Method for producing protein polysaccharide having antitumor activity,'' and JP-A-55-74797, ``Production method for protein polysaccharide having antitumor activity.''

Kawariharatake used in the present invention is the 120th
No. 7227 (title of invention: method for cultivating mushrooms of the genus Agaricus). The basidiomycete was collected in the suburbs of Piedate, São Paulo state, Brazil, and has already been submitted to the Institute of Microbiology, Agency of Industrial Science and Technology. It is registered as Microtechnology Research Institute No. 4731.

Kawariharatake is a common edible mushroom that is delicious and nutritionally superior, but it has also been discovered that an aqueous solvent extract of this mushroom has extremely significant antitumor properties.

(■ Hitoshi Ito: Patent No. 1442648.

■ Hitoshi Ito et al.: Article from the 39th Annual Meeting of the Japanese Cancer Society, :350
Page, 1980.

■ Hitoshi Ito et al.: Japan J, Pharmacol
, : 31 (Suppl: 170 pages, 1981.

■ Hitoshi Ito et al.: Infectious Diseases: Vol. 14 Nα1, p. 18, 198
4 years.

■ Hitoshi Ito et al.: Japan J, Phar+++ac
o1. ．． 33 (Suppl).

149 pages, 1983.

■ Hitoshi Ito et al.: Japan J, Pharmac
ol, : 33 volumes.

403 pages, 1983.

■ Hitoshi Ito et al.: Article from the 43rd Annual Meeting of the Japanese Cancer Society, : 27
9 pages, 1984.

■Hitoshi Ito et al.: Medicine and Biology, Volume 109, N115,
299 pages.

1984.

■ Hitoshi Ito et al.: Collection of lecture abstracts from the 10th Carbohydrate Symposium,
: B3, 1987, ) [Phase] Hitoshi Ito et al.: Article from the 47th Annual Meeting of the Japanese Cancer Society, :
(Page 503, 1988 Hitoshi Ito: Patent No. 1442647) In other words, Kawari Haritake has the effect of activating immune activity in the human body, and is effective against ascites-type tumors, including solid tumors, where other mushrooms are ineffective. It was found to have medicinal properties.

In addition, liver function improving effect, complement third component activating effect, reticuloendothelial system function activating effect, antidiabetic effect, cardiac function improving effect, intestinal fly motility promoting effect, interferon inducing effect, macroferon activating effect, Interesting pharmacological effects have been accumulated and have already been published, such as strengthening biological host resistance mechanisms such as cellular immunity and humoral immune activation.

The present invention provides a functional food containing the fruiting body of Kawariharatake and the protein polysaccharide contained in the dried product of the fruiting body.

(2) Regarding the structure, operation, and effects of the invention.

Hereinafter, details of the present invention will be explained based on examples.

The fruiting bodies of Kawariharatake are dried immediately after collection and can be provided to general users with a moisture content of 8% or less. This product condition not only reduces weight but also provides favorable conditions for preventing bacterial growth and deterioration, making it the optimal product form for storage and distribution. Therefore, when using the fruiting body of Kawariharatake as a food, the starting point is the raw fruiting body immediately after collection or its dried product.

The fruiting bodies of Kawariharatake are delicious and nutritious, so like shiitake, they can be used as edible raw materials. For example, by adding a few seasonings, it can be used as the main ingredient in a dish or as an accompaniment. Furthermore, it can be cut into small pieces or powdered and used as a paste, furikake, etc. In either case, the food contains a large amount of protein polysaccharide, making it a food with high value as a functional food. Furthermore, these raw materials are placed in water-permeable bags such as paper bags or cloth bags, filled and packaged, and then commercialized like tea bags, and consumers can easily extract the ingredients by hand to make beverages. It can also be used for.

Next, extracting the raw material of the fruiting body of Kawariharatake with an aqueous solvent and consuming the extract as it is or after concentrating it is a rational method of utilization that does not impair the quality of the original ingredients of the raw material.

In this case, animal tests have generally shown that the more the protein polysaccharide obtained from the mushroom itself is purified, the less its antitumor effect becomes. It is more effective to use the protein polysaccharide components of mushrooms. The aqueous solvent may be water, alcohol, a mixture thereof, or the like. If it is used as a health drink such as an alcoholic beverage or tea, it becomes a food with high value as a functional food.

The aqueous solvent extract of the fruiting body raw material of Kawariharatake can not only be used as is as a beverage, but also can be added to food processing raw materials to produce functional foods in the form of processed foods. For example, it can be added to bouillon to make soup, mixed with starch syrup to make candy, etc.
A variety of foods such as... can be considered, and any of them can provide a food with high value as a functional food.

When using the above-mentioned various foods, the amount of tangerine eaten or drunk per serving is 7 to 1. Og is an appropriate amount to exhibit an antitumor effect, and this equivalent amount is also considered to be appropriate for the amount of extract.

Even if more than this is removed, there will be no problem at all.

Example-1 1.8 liters of water, 24 g of agar, and 6.0 liters of soy sauce as a seasoning liquid for Kawariharatake Tsukudani.
Boil and dissolve 3 liters, 17 kg of starch syrup, and 2.25 kg of sugar. Reconstitute JM's dried Kawariharatake mushrooms in water with a small amount of sugar added, add the seasoning liquid, and simmer until the liquid evaporates, being careful not to burn.

Example-2 8 liters of Kawariharatake furikake soy sauce, 100g of sodium glutamate, sand I,
If 1 kg is boiled to make a seasoning liquid.

Agaric agaric powder, or in some cases a mixture of powdered fish meat such as horse mackerel, is placed in a boiling pot, an appropriate amount of the seasoning liquid is added, and the mixture is seasoned and boiled for about 40 minutes. This is passed through a sieve to uniformize the particles, then put into a dryer and dried at 80°C for 2 hours. If necessary, add kelp, green seaweed, sesame seeds, etc., and package in moisture-proof packaging.

Example 3 Agaricus tea Dried Agaricus powder was sealed in a small bag made of non-woven fabric and packaged in moisture-proof packaging. The appropriate amount of Kawariharatake powder in the bag to drink is 7 to log a day. When drinking, place one bag in a pot with about 400 ml of water, heat and extract for 15 minutes while adding water occasionally to prevent boiling over, then cool and reduce the total volume of the extract to 300 ml. Divide this into 2 to 3 times a day and drink it. When drinking, add a small amount of salt to make it even more delicious.

Example 4 Agaricus Beverage Approximately 40 kg of water is added to 1 kg of dried agaricus mushrooms, and the mixture is allowed to absorb enough water, heated for 2 to 3 hours while occasionally replenishing water, and then filtered as appropriate. If you use powder, you can shorten the heating time and do the same thing.

The total volume of extract should be approximately 30 kg.

This is used as a hot water extract.

Next, for example, 14 saccharides are added to 1 kg of this hot water extract.
0 g, honey 15 g, caramel 5 g, ascorbic acid 0
．． Add 75 g, 0.3 g of citric acid, and appropriate amount of fragrance, 93
Sterilize at ℃ for 20 minutes and fill aseptically into cans or bottles.

The above formulation also contains other healthful extracts, such as Reishi,
This does not preclude the addition of extracts such as Amacha and Crane as appropriate.

Example 5 Kawari agaric liquor 5 to 10 kg of rock sugar is added to 1 kg of dried Kawari agaric, roughly chopped as appropriate, and 8 liters of shochu or white liquor I is gently poured into the product, sealed and stored.

After 3-4 weeks, it is filtered and bottled.

Drink 30-50+il at a time.

Example 6 Kawariharatake candy 25kg of the Kawariharatake hot water extract shown in Example 4 was added to 50kg of sugar, boiled completely, and then starch syrup 7.
Add 5 kg and bring to a boil. Once it has solidified by dropping it into cold water, remove it from the heat and add the colorants, fragrances, etc. as needed.
Add acidulant etc. This is cooled and molded on an oiled cooling plate or tablet holder.

In addition, instead of using Kawariharatake hot water extract,
It is also possible to add the concentrate or powder suspended in water.

Claims (3)

[Claims] (1) A functional food containing protein polysaccharide components unique to Kawariharatake, obtained by cutting the fruiting body of Kawariharatake into small pieces or pulverizing the dried product of the fruiting body. (2) A functional food containing the fruiting body of Kawariharatake mushroom and a liquid obtained by extracting the dried fruiting body with an aqueous solvent. (3) A functional food made by adding the liquid obtained by extracting the fruiting body of Kawariharatake or the dried product of the fruiting body with an aqueous solvent to raw materials for food processing, either as it is or after concentrating it.