JPS6069026A - Health food containing antitumor components from "himematsutake" - Google Patents

Health food containing antitumor components from "himematsutake"

Info

Publication number
JPS6069026A
JPS6069026A JP58177027A JP17702783A JPS6069026A JP S6069026 A JPS6069026 A JP S6069026A JP 58177027 A JP58177027 A JP 58177027A JP 17702783 A JP17702783 A JP 17702783A JP S6069026 A JPS6069026 A JP S6069026A
Authority
JP
Japan
Prior art keywords
himematsutake
food
health food
dried
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58177027A
Other languages
Japanese (ja)
Inventor
Yoriyasu Ubata
羽端 自耕
Inosuke Iwade
岩出 亥之助
Hitoshi Ito
均 伊藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NICHIJIYOU KK
Original Assignee
NICHIJIYOU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NICHIJIYOU KK filed Critical NICHIJIYOU KK
Priority to JP58177027A priority Critical patent/JPS6069026A/en
Publication of JPS6069026A publication Critical patent/JPS6069026A/en
Pending legal-status Critical Current

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  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PURPOSE:A health food that contains fruit bodies of HIMEMATSUTAKE (a kind of edible mushroom originating from Brazil) or its dried product as such or in the form of a powder or extract by aqueous medium extraction, thus showing antitumor properties. CONSTITUTION:Fruits bodies of HIMEMATSUTAKE or their dried products are cut into pieces or powdered and added to food products. Or the mushrooms are extracted with an queous solution and the extract is used as such or in the form of a concentrate and the concentrate is added to food products to give the objective health food. HIMEMATSUTAKE is tasty as an edible mushroom rich in nutrition, further found to have excellent antitumor activity. Namely, the beta-(1 3)glucan has the action of activating immune activity in human bodies to show excellent antitumor action not only on solid cancer but also ascites cancers to which other mushrooms are inactive. The suitable amount of the health food to be taken is such an amount as to correspond to 7-10g of dried HIMERATSUTAKE.

Description

【発明の詳細な説明】 本発明はヒメマツタケに含まれる抗腫瘍性成分を含ませ
た食品に811フる。詳しくは本発明者の一人が栽培に
成功したハラタケ科ハラタケ属の^garicus b
lazei Hurrlllに含まれる抗Ill瘍作用
の顕著な蛋白多糖体を利用する目的をもって、その子実
体、子実体の乾燥品をそのままあるいは粉末化して添加
するか、あるいは間接的に水性溶媒で抽出した液を使用
するII東食品に関するものである。本発明者の一人は
以下経過説明に引用するいくつかの特許を申請済であり
、本特許はそれらの申請情緒特許の一部追加発明に係る
DETAILED DESCRIPTION OF THE INVENTION The present invention provides a food containing an antitumor component contained in Hiematsutake. For details, see ^garicus b, a member of the family Agaricaceae, which was successfully cultivated by one of the present inventors.
For the purpose of utilizing the protein polysaccharide with remarkable anti-Illulcer effect contained in Lazei Hurrll, the fruiting body and dried product of the fruiting body can be added as is or powdered, or the liquid extracted indirectly with an aqueous solvent can be added. This is related to II East Foods used. One of the present inventors has applied for several patents referred to in the progress description below, and this patent relates to an additional invention in part to those applied emotion patents.

本発明において用いられるヒメマツタケは、本発明者の
一人がはじめて人工栽培に成功し、その栽培法の一部は
申請済の特公昭35−138853に記載されている。
One of the present inventors succeeded in artificially cultivating the Himematsutake used in the present invention for the first time, and a part of the cultivation method is described in Japanese Patent Publication No. 35-138853, which has already been filed.

その担子菌は、ブラジル国すンパウロ州ビエダーテ市郊
外で採取されたもので、既に工業技術院微生物工業研究
所に第4731号として登録されている。
The basidiomycete was collected in the suburbs of Viedate, São Paulo state, Brazil, and has already been registered as No. 4731 at the Institute of Microbiology, Agency of Industrial Science and Technology.

ヒメマツタケは普通の食用キノコとしても美味で栄養的
にもすぐれたものがあるが、さらにこのキノコの水性溶
媒抽出液が極めてfI@な抗腫瘍性を有することがわか
った。即ち、ヒメマツタケはその多糖体であるβ−(1
→3)グルカンが人体の免疫活性を賦活する作用を有し
、固形l!瘍をはじめ他のキノコ類では効果のない腹水
型l!瘍にも著効を示すことがわかった。本発明者の一
人は、この水性溶媒抽出液などから抗l!瘍性有効成分
の主体である蛋白多糖体を採取することについて申請済
の特開昭55−74797 (9[1連特開昭55−1
08292、特開昭55−108293>に記載してい
る。これは抽出液から蛋白多糖体として沈澱し、あるい
はさらに精製して利用する方法であり、特に医薬品とし
て治療用に使用づる場合には適した方法である。
Himematsutake is a common edible mushroom that is delicious and nutritious, but it has also been found that an aqueous solvent extract of this mushroom has extremely antitumor properties. That is, Himematsutake has its polysaccharide β-(1
→3) Glucan has the effect of activating the immune activity of the human body, and solid l! Ascites type l, which is not effective against other mushrooms including ulcers! It was also found to be effective against cancer. One of the inventors of the present invention obtained anti-l! from this aqueous solvent extract. JP 55-74797 (9 [1 series JP 55-1
08292, JP-A-55-108293>. This is a method in which the protein polysaccharide is precipitated from the extract or further purified for use, and is particularly suitable for therapeutic use as a pharmaceutical.

以下、本発明の詳細を実施例に基づいて説明する。Hereinafter, details of the present invention will be explained based on examples.

ヒメマツタケの生産者は、子実体採取後直ちに乾燥し8
%以下の水分含量にして一般利用者に提供している。こ
の製品状態は軽量化が達成できるばか細菌の繁殖、変敗
の防止に対しても好条件であり、保存上、流通上最適の
商品形態とされている。したがってヒメマツタケ子実体
を食品として利用する場合の出発点は、ずべて子実体の
採取直後のなまの状態あるいはその乾燥品からである。
Producers of Himematsutake must dry the fruiting body immediately after collecting it.
% or less and is provided to general users. This product condition is ideal for reducing weight, preventing the proliferation of bacteria, and preventing spoilage, and is considered to be the optimal product form for storage and distribution. Therefore, the starting point for using the fruiting body of Himematsutake as a food is always the raw state immediately after harvesting the fruiting body or its dried product.

ヒメマツタケの子実体は興味かつ栄養的なのでシイタケ
同様、原料形態のままで食用に利用できる。たとえば、
多少の調味料を加えるだけで料理の主役にも付合せにも
使用できる。さらに小片状に切断したものあるいは粉末
化したものは、ベースト、ふりかけなどにして使用でき
る。伺れにも抗腫瘍成分を多量に含むので、am食品と
しての価値の高い食品となる。さらにこれらの原料形体
のまま紙袋あるいは布袋のような水を透過する袋に入れ
て充填包装し、紅茶のティーバックのように商品化し、
消費各自からの手で容易に成分を抽出して飲料に用いる
ことも可能である。
The fruiting body of Himematsutake is interesting and nutritious, and like shiitake, it can be used as a raw material for food. for example,
With just a few seasonings, it can be used as the main ingredient in a dish or as an accompaniment. Furthermore, it can be cut into small pieces or powdered and used as a base, furikake, etc. It also contains a large amount of antitumor components, making it a highly valuable am food. Furthermore, these raw materials are placed in water-permeable bags such as paper bags or cloth bags, filled and packaged, and commercialized like tea bags.
It is also possible for consumers to easily extract the components manually and use them in beverages.

次にヒメマツタケの子実体原料を一旦水性溶媒で抽出し
、その抽出液をそのままあるいは濃縮して食用に供する
ことは、原料本来の成分の品質をそこなわず合理的な利
用方法である。一般に動物試験によればキノコ自体から
得た蛋白多糖体は精製を重ねるほど抗腫瘍効果が低下す
ることが認められているので、医薬品に使用する場合と
異なり精製を重ねず使用するほうがキノコの抗腫瘍性成
分を有効に利用できる。水性溶媒は水、アルコール、そ
の混合物などいづれでもよい。アルコール、飲料、茶な
どの鍵部飲料として価値の高いilI!i食品となる。
Next, extracting the raw material of the fruiting body of the Himematsutake mushroom with an aqueous solvent and consuming the extract as it is or after concentrating it is a rational method of utilization without sacrificing the quality of the original components of the raw material. In general, animal studies have shown that the more the protein polysaccharide obtained from the mushroom itself is purified, the less its antitumor effect becomes. Tumor components can be used effectively. The aqueous solvent may be water, alcohol, a mixture thereof, or the like. ILI is highly valuable as a key part beverage such as alcohol, beverages, and tea! It becomes an i-food.

ヒメマツタケの子実体原料の水性溶媒抽出液はそのまま
飲料として利用できるばかりでなく、食品加工原料に添
加して加工食品の形の健康食品を製造することも可能で
ある。たとえばブイヨンに添加混合してスープを製造、
水飴に混入して飴を製造・・・・・・など種々のものが
考えられ、何れも健康食品として価値の高い食品が得ら
れる。
The aqueous solvent extract of the fruiting body raw material of Himematsutake can not only be used as a beverage as it is, but also can be added to food processing raw materials to produce health foods in the form of processed foods. For example, by adding and mixing with bouillon to make soup,
Various methods can be considered, such as mixing it with starch syrup to produce candy, etc., and all of them can yield foods with high value as health foods.

以上の種々の食品としての利用にあたって、摂食ないし
飲用量は1回あたりヒメマツタケ乾燥品として1〜10
9が抗ms効果を発揮する適当量であり、抽出液φにつ
いても乾燥品7〜109相当優が適当とみられる。それ
以上過剰に摂取しても与えられる障害は全くない。
When using the various food products mentioned above, the amount of ingestion or drinking is 1 to 10% of dried Himematsutake per serving.
9 is the appropriate amount to exhibit the anti-ms effect, and it is considered that the appropriate amount for the extract φ is 7 to 109 equivalent to the dry product. Even if taken in excess, there is no harm caused.

実施例1 ヒメマツタケつくだに 調味液として水18L寒天249、しよう油6.3オ、
水飴17XIF、砂糖2.25kgを煮てとかしておく
。原料の乾燥ヒメマツタケに少量の砂糖を加えた水でも
どし、これに調味液を加えて焦げつかないように煮汁が
なくなるまで煮る。
Example 1 Seasoning liquid for Himematsutake Tsukuda: 18L of water, 249L of agar, 6.3L of soybean oil,
Boil and dissolve 17XIF starch syrup and 2.25 kg of sugar. The raw material, dried Himematsutake, is rehydrated in water with a small amount of sugar added, then the seasoning liquid is added to this and boiled until the liquid evaporates, taking care not to burn it.

実施例2 ヒメマツタケふりかけ しょう油81にグルタミン酸ソーダ100g、砂1i1
11を煮とかした調味液をつくる。ヒメマツタケ粉末、
あるいは場合によってはこれにアジなどの魚肉粉末を加
えて煮釜に入れ、前記調味液を適当量加えて約409聞
調味煮熱する。これをふるい機にかけて粒子をそろえた
上で乾燥機にかけ、80℃で21j1m乾燥する。場合
によってはこれにコンブ、胃のり、ゴマなども加えて防
湿包装する。
Example 2 Himematsutake furikake soy sauce 81, sodium glutamate 100g, sand 1i1
Make a seasoning liquid by boiling 11. Himematsutake powder,
Alternatively, depending on the case, powdered fish meat such as horse mackerel is added to the mixture, placed in a boiling pot, an appropriate amount of the seasoning liquid is added, and the mixture is boiled for about 40 minutes. This is passed through a sieve to align the particles, then put into a dryer and dried at 80°C over a length of 21m. In some cases, kelp, stomach seaweed, sesame seeds, etc. are added to this and packaged in moisture-proof packaging.

実施例3 ヒメマツタケ基 乾燥ヒメマツタケ粉末を不織布で作った小袋に封入し、
防湿包装する。袋中のヒメマツタケ粉末量は1日飲用水
として7〜109が適当である。飲用時にはこの袋1ヶ
を鋼に水約400dと共に入れ吹きこぼれないように時
々水を加えながら加熱抽出15分後、冷却、抽出液全量
を300d <らいにする。これを1日2〜3回にわけ
て飲用する。飲用時、生学の食塩を加えると更に美味に
なる。
Example 3 Dried Himematsutake powder was sealed in a small bag made of non-woven fabric,
Pack moisture-proof. The appropriate amount of Himematsutake powder in the bag is 7 to 109 points per day for drinking water. When drinking, place one bag in a steel container with about 400 ml of water, add water occasionally to prevent boiling over, heat and extract for 15 minutes, then cool and bring the total volume of the extracted liquid to 300 ml. Divide this into 2 to 3 times a day and drink it. It becomes even more delicious when you add raw salt when drinking.

実施例4 ヒメマツタケ飲料 乾燥ヒメマツタケ1Kgに水約4089を加え、十分吸
水させてから2〜3時間、時々水を補給しながら加熱後
、適宜線通する。粉末を使えば加熱時間を短縮して同様
に操作できる。前抽出液をほぼ30Kg程度になるよう
にする。これを熱水抽出液とする。
Example 4 Himematsutake beverage Approximately 4,089 grams of water is added to 1 kg of dried Himematsutake, and the mixture is allowed to absorb enough water, then heated for 2 to 3 hours while occasionally replenishing water, and then passed through a wire as appropriate. If you use powder, you can shorten the heating time and do the same thing. Adjust the amount of pre-extract to approximately 30 kg. This is used as a hot water extract.

次にこの熱水抽出液1Kgに対し、たとえば糖類14G
9 、蜂蜜15g、カラメル5g、アスコルビン酸0.
759、クエン酸0.3g、香料適量を加え、93℃で
20分殺菌し、無菌的に缶またはびんに充填する。なお
、上記配合には弛の健康性抽出物、たとえば霊芝、アマ
チャ・ヅルなどの抽出物を適宜添加づることを妨げるも
のではない。
Next, for example, 14G of saccharide is added to 1Kg of this hot water extract.
9, honey 15g, caramel 5g, ascorbic acid 0.
759, 0.3 g of citric acid, and an appropriate amount of fragrance are added, sterilized at 93°C for 20 minutes, and aseptically filled into cans or bottles. It should be noted that this does not preclude the addition of appropriate health extracts of Reishi, such as extracts of Ganoderma lucidum, Amacha chinensis, etc., to the above-mentioned formulation.

実施例5 ヒメマツタケ酒 ヒメマツタケ乾燥品を適宜に粗に611んだもの1KH
に対して、好みにより氷砂糖5〜10Kgを加え、焼酎
またはホワイト・リカー181を静かに注入して密封、
貯蔵づる。3〜4週間経過後罐過し、びん詰とする。1
回30〜50dを飲用する。
Example 5 Himematsutake sake 1KH of dried Himematsutake that was coarsely ground as appropriate
Add 5 to 10 kg of rock sugar depending on your preference, gently pour in shochu or white liquor 181, and seal.
Storage vine. After 3 to 4 weeks, it is filtered and bottled. 1
Drink 30-50d.

実施例6 ヒメマツタケ飴 砂糖50Kyに実施例4に示したヒメマツタケ熱水抽出
液25腹を加えて完全に煮とかし、さらに水飴7.5K
gを加えて煮つめる。冷水中に滴下して固まる程度にな
ったら、火がらおろし、場合によっては色素、香料、酸
味料などを加える。これを油をひいた冷却盤またはタブ
レット機にかけて冷却整型する。
Example 6 25 tons of the hot water extract of Himematsutake shown in Example 4 was added to 50Ky of Himematsutake candy sugar, boiled completely, and then 7.5K of starch syrup was added.
Add g and bring to a boil. Once it has solidified by dropping it into cold water, grate it off the heat and add coloring matter, flavoring, acidulant, etc. as the case may be. This is cooled and shaped on an oiled cooling plate or tablet machine.

なお、ヒメマツタケ熱水抽出液を使用するかわりに、そ
の濃縮物、あるいは粉末を水に懸濁させて加えることも
可能である。
Note that instead of using the hot water extract of Himematsutake, it is also possible to suspend its concentrate or powder in water and add it.

Claims (1)

【特許請求の範囲】 1、ヒメマツタケの子実体、子実体の乾燥品を小片状に
切断あるいは細粉化して、ヒメマツタケ特有の抗腫瘍性
成分をそのまま食用に供する形の41!I!i食品。 2、ヒメマツタケの子実体、子実体の乾燥品を水性溶液
で抽出して得られる液をそのまま、あるいはt縮して食
用に供する形の111食品。 3、ヒメマツタ、ケの子実体、子実体の乾燥品を水性溶
媒で抽出して得られる液をそのまま、あるいは濃縮して
食品加工原料に添加し、ヒメマツタケ特許Jの抗腫瘍性
成分を含む加工食品を製造してなる形の健康食品。
[Claims] 1. 41! The fruiting body of Himematsutake, the dried product of the fruiting body is cut into small pieces or finely powdered, and the anti-tumor component unique to Himematsutake is directly edible! I! i-food. 2. 111 food in the form of a liquid obtained by extracting the fruiting body of Himematsutake or a dried product of the fruiting body with an aqueous solution, which can be eaten as is or after being compressed. 3. A processed food containing the anti-tumor ingredient of Patent J of Patent J by adding the liquid obtained by extracting the fruiting bodies and dried fruiting bodies of Patentia chinensis with an aqueous solvent to raw materials for food processing, either as is or after concentrating the liquid. A health food made by manufacturing.
JP58177027A 1983-09-27 1983-09-27 Health food containing antitumor components from "himematsutake" Pending JPS6069026A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP58177027A JPS6069026A (en) 1983-09-27 1983-09-27 Health food containing antitumor components from "himematsutake"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58177027A JPS6069026A (en) 1983-09-27 1983-09-27 Health food containing antitumor components from "himematsutake"

Publications (1)

Publication Number Publication Date
JPS6069026A true JPS6069026A (en) 1985-04-19

Family

ID=16023868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58177027A Pending JPS6069026A (en) 1983-09-27 1983-09-27 Health food containing antitumor components from "himematsutake"

Country Status (1)

Country Link
JP (1) JPS6069026A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6356267A (en) * 1986-08-27 1988-03-10 Yukio Kobayashi Food additive substance
JPH02203765A (en) * 1989-02-02 1990-08-13 Nippon Beet Sugar Mfg Co Ltd Food having antitumor function and production thereof
JPH02211848A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component of agaricus blazei
JPH02211847A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component separated from mycelium of cultured agaricus blazei
JPH02211846A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component separated from filtrate of cultured agaricus blazei
US5048227A (en) * 1988-05-05 1991-09-17 Junya Okubo Method of cultivating agaricus blazei mushroom
JPH06239761A (en) * 1993-02-12 1994-08-30 Hitoshi Ito Agent for internal use, food and drink having appetite stimulating action
CN104366450A (en) * 2014-11-17 2015-02-25 陶胜 Making method of multi-flavor mushroom crystal

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6356267A (en) * 1986-08-27 1988-03-10 Yukio Kobayashi Food additive substance
US5048227A (en) * 1988-05-05 1991-09-17 Junya Okubo Method of cultivating agaricus blazei mushroom
JPH02203765A (en) * 1989-02-02 1990-08-13 Nippon Beet Sugar Mfg Co Ltd Food having antitumor function and production thereof
JPH02211848A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component of agaricus blazei
JPH02211847A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component separated from mycelium of cultured agaricus blazei
JPH02211846A (en) * 1989-02-10 1990-08-23 Iwade Kingaku Kenkyusho:Kk Functional food containing protein polysaccharide component separated from filtrate of cultured agaricus blazei
JPH06239761A (en) * 1993-02-12 1994-08-30 Hitoshi Ito Agent for internal use, food and drink having appetite stimulating action
CN104366450A (en) * 2014-11-17 2015-02-25 陶胜 Making method of multi-flavor mushroom crystal

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