JPH02138226A - ヒトの線維芽細胞インタフェロン含有医薬組成物 - Google Patents

ヒトの線維芽細胞インタフェロン含有医薬組成物

Info

Publication number
JPH02138226A
JPH02138226A JP1258989A JP25898989A JPH02138226A JP H02138226 A JPH02138226 A JP H02138226A JP 1258989 A JP1258989 A JP 1258989A JP 25898989 A JP25898989 A JP 25898989A JP H02138226 A JPH02138226 A JP H02138226A
Authority
JP
Japan
Prior art keywords
interferon
column
units
sepharose
human fibroblast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1258989A
Other languages
English (en)
Japanese (ja)
Inventor
Heinz-Juergen Friesen
ハインツ‐ユールゲン・フリーゼン
Sidney Pestka
シドニイ・ペストカ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPH02138226A publication Critical patent/JPH02138226A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP1258989A 1979-07-31 1989-10-05 ヒトの線維芽細胞インタフェロン含有医薬組成物 Pending JPH02138226A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6237179A 1979-07-31 1979-07-31
US62371 1979-07-31
US13063580A 1980-03-14 1980-03-14
US130635 1993-10-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP10379380A Division JPS5622794A (en) 1979-07-31 1980-07-30 Human fibroblast interferon

Publications (1)

Publication Number Publication Date
JPH02138226A true JPH02138226A (ja) 1990-05-28

Family

ID=26742182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1258989A Pending JPH02138226A (ja) 1979-07-31 1989-10-05 ヒトの線維芽細胞インタフェロン含有医薬組成物

Country Status (33)

Country Link
US (1) US5015730A (cg-RX-API-DMAC10.html)
JP (1) JPH02138226A (cg-RX-API-DMAC10.html)
AR (1) AR229931A1 (cg-RX-API-DMAC10.html)
AT (1) AT372387B (cg-RX-API-DMAC10.html)
AU (1) AU536274B2 (cg-RX-API-DMAC10.html)
CA (1) CA1146468A (cg-RX-API-DMAC10.html)
CH (1) CH648331A5 (cg-RX-API-DMAC10.html)
DE (1) DE3028919A1 (cg-RX-API-DMAC10.html)
DK (1) DK159825C (cg-RX-API-DMAC10.html)
DO (1) DOP1980002948A (cg-RX-API-DMAC10.html)
ES (1) ES8200560A1 (cg-RX-API-DMAC10.html)
FI (1) FI70721C (cg-RX-API-DMAC10.html)
FR (1) FR2462167B1 (cg-RX-API-DMAC10.html)
GB (1) GB2055384B (cg-RX-API-DMAC10.html)
HK (1) HK40384A (cg-RX-API-DMAC10.html)
HU (1) HU185382B (cg-RX-API-DMAC10.html)
IE (1) IE50075B1 (cg-RX-API-DMAC10.html)
IL (1) IL60697A (cg-RX-API-DMAC10.html)
IT (1) IT1132269B (cg-RX-API-DMAC10.html)
KE (1) KE3364A (cg-RX-API-DMAC10.html)
LU (1) LU82673A1 (cg-RX-API-DMAC10.html)
MC (1) MC1337A1 (cg-RX-API-DMAC10.html)
MY (1) MY8500274A (cg-RX-API-DMAC10.html)
NL (1) NL8004361A (cg-RX-API-DMAC10.html)
NO (1) NO151158C (cg-RX-API-DMAC10.html)
NZ (1) NZ194495A (cg-RX-API-DMAC10.html)
PH (2) PH17738A (cg-RX-API-DMAC10.html)
PT (1) PT71625B (cg-RX-API-DMAC10.html)
RO (1) RO81474B (cg-RX-API-DMAC10.html)
SE (1) SE466290B (cg-RX-API-DMAC10.html)
YU (1) YU193480A (cg-RX-API-DMAC10.html)
ZA (1) ZA803943B (cg-RX-API-DMAC10.html)
ZW (1) ZW17980A1 (cg-RX-API-DMAC10.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170476B1 (da) 1980-04-03 1995-09-11 Biogen Inc Rekombinant DNA-molekyle, uni-cellulær vært transformeret med mindst ét rekombinant DNA-molekyle, fremgangsmåde til transformering af en uni-cellulær vært, samt fremgangsmåder til fremstilling af et polpeptid, der udviser den immunologiske eller biologiske aktivitet af human beta-interferon
NZ198445A (en) * 1980-09-25 1984-05-31 Genentech Inc Production of human fibroblast interferon by recombinant dna technology
ZA83768B (en) * 1982-03-01 1983-10-26 Hoffmann La Roche Homogeneous human immune interferon and process therefor
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US20030026779A1 (en) * 1999-10-15 2003-02-06 Liming Yu Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
US20050002902A1 (en) * 1995-12-28 2005-01-06 Liming Yu Hybrid with interferon-alpha and an immunoglobulin Fc for treatment of tumors and viral infections
US20080219952A1 (en) 2005-08-26 2008-09-11 Ares Trading S.A. Process For the Preparation of Glycosylated Interferon Beta
JP5199112B2 (ja) 2005-12-09 2013-05-15 アレス トレーディング ソシエテ アノニム Fsh又はfsh変異体を精製するための方法
CA2702448A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CANCER TREATMENT REPORTS=1978 *
J.BIOL.CHEM=1977 *
J.BIOL.CHEM=1978 *

Also Published As

Publication number Publication date
CH648331A5 (de) 1985-03-15
LU82673A1 (fr) 1982-02-17
IL60697A0 (en) 1980-09-16
DK159825C (da) 1991-04-29
FI802400A7 (fi) 1981-02-01
ZA803943B (en) 1981-06-24
FI70721C (fi) 1986-10-06
IE50075B1 (en) 1986-02-05
DK328880A (da) 1981-02-01
CA1146468A (en) 1983-05-17
PH18479A (en) 1985-07-18
FR2462167B1 (fr) 1985-07-05
AU536274B2 (en) 1984-05-03
FI70721B (fi) 1986-06-26
NO151158C (no) 1985-02-20
AT372387B (de) 1983-09-26
AU6091480A (en) 1981-02-05
IT1132269B (it) 1986-07-02
ATA395080A (de) 1983-02-15
SE466290B (sv) 1992-01-27
NO151158B (no) 1984-11-12
RO81474B (ro) 1983-04-30
MC1337A1 (fr) 1981-04-21
PT71625A (en) 1980-08-01
DOP1980002948A (es) 1989-04-20
IE801589L (en) 1981-01-31
IL60697A (en) 1984-04-30
DE3028919A1 (de) 1981-02-19
DK159825B (da) 1990-12-10
SE8005498L (sv) 1981-02-01
ZW17980A1 (en) 1981-03-18
IT8023801A0 (it) 1980-07-30
NO802297L (no) 1981-02-02
RO81474A (ro) 1983-04-29
KE3364A (en) 1984-02-03
NL8004361A (nl) 1981-02-03
PT71625B (en) 1981-12-17
FR2462167A1 (fr) 1981-02-13
HU185382B (en) 1985-01-28
US5015730A (en) 1991-05-14
GB2055384A (en) 1981-03-04
NZ194495A (en) 1984-07-31
GB2055384B (en) 1983-08-10
HK40384A (en) 1984-05-18
ES493849A0 (es) 1981-11-16
YU193480A (en) 1984-04-30
AR229931A1 (es) 1984-01-31
DE3028919C2 (cg-RX-API-DMAC10.html) 1988-02-18
ES8200560A1 (es) 1981-11-16
PH17738A (en) 1984-11-23
MY8500274A (en) 1985-12-31

Similar Documents

Publication Publication Date Title
FI69476B (fi) Foerfarande foer rening av maenniskans leukocyt-interferon
JP3438735B2 (ja) 上清iv、特にiv−4またはコーンフラクションvまたはそれと類似の上清または画分からヒトアルブミンを単離する方法
CA1146468A (en) Homogeneous fibroblast interferon and method for manufacture thereof
HU212362B (en) Methods for preparing coagulation factor ix and pharmaceutical compositions containing same
KR0131204B1 (ko) 암 면역치료용 보조제
NZ203364A (en) Method for purifying human immune interferon;homogeneous human immune interferon
US4617378A (en) Purification of biologically active human immune interferon
EP0446582A1 (en) Method for producing of recombinant human cysteineless gamma-interferon free of methionine at n-terminal
JPS6261040B2 (cg-RX-API-DMAC10.html)
US5114710A (en) M-csf as a therapeutic agent for thrombocytopenia
JPH02115196A (ja) エリスロポエチンの精製法
JPH0224840B2 (cg-RX-API-DMAC10.html)
US4723000A (en) Human interferon gamma and interleukin-2
JPWO1992014832A1 (ja) ヒトbcdfの精製法
US20030148488A1 (en) Method for the production of pure virally inactivated butyrylcholinesterase
JPH0568583A (ja) 組換えヒトβ−インターフエロンの精製方法
Herring et al. Rapid purification of leukocyte interferons by high-performance liquid chromatography
Miroshnikov et al. Preparation of Interferon-γ and Deltaferon, Its Analogue