JPH0211105B2 - - Google Patents

Info

Publication number
JPH0211105B2
JPH0211105B2 JP58126840A JP12684083A JPH0211105B2 JP H0211105 B2 JPH0211105 B2 JP H0211105B2 JP 58126840 A JP58126840 A JP 58126840A JP 12684083 A JP12684083 A JP 12684083A JP H0211105 B2 JPH0211105 B2 JP H0211105B2
Authority
JP
Japan
Prior art keywords
methyl
compounds
radiolabeled
acid
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58126840A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5924257A (ja
Inventor
Aaru Tozodeiko Neisan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of JPS5924257A publication Critical patent/JPS5924257A/ja
Publication of JPH0211105B2 publication Critical patent/JPH0211105B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121Solutions, i.e. homogeneous liquid formulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58126840A 1982-07-12 1983-07-12 カルボニル化ジエチレントリアミンを用いる放射性標識化合物安定化のための組成物 Granted JPS5924257A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/397,501 US4411881A (en) 1982-07-12 1982-07-12 Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines
US397501 1982-07-12

Publications (2)

Publication Number Publication Date
JPS5924257A JPS5924257A (ja) 1984-02-07
JPH0211105B2 true JPH0211105B2 (enExample) 1990-03-12

Family

ID=23571454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58126840A Granted JPS5924257A (ja) 1982-07-12 1983-07-12 カルボニル化ジエチレントリアミンを用いる放射性標識化合物安定化のための組成物

Country Status (7)

Country Link
US (1) US4411881A (enExample)
JP (1) JPS5924257A (enExample)
CA (1) CA1205070A (enExample)
CH (1) CH655853A5 (enExample)
DE (1) DE3324593C2 (enExample)
FR (1) FR2536998B1 (enExample)
GB (1) GB2123412B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3331159A1 (de) * 1983-08-30 1985-03-14 Hoechst Ag, 6230 Frankfurt N-(4-aminobenzoyl)-aminodicarbonsaeuren zur stabilisierung von technetium-99m-praeparaten, stabilisierte injektionspraeparate und verfahren zu ihrer herstellung
US4656280A (en) * 1984-03-07 1987-04-07 E. I. Du Pont De Nemours And Company Radioiodinated dopamine receptor ligand
GB8510726D0 (en) * 1985-04-26 1985-06-26 Amersham Int Plc Stabilised radio-labelled compounds
JPH0317229U (enExample) * 1989-06-30 1991-02-20
MC2260A1 (fr) * 1990-06-18 1993-04-26 Dow Chemical Co Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
AU9172191A (en) * 1990-12-12 1992-07-08 Mallinckrodt Medical, Inc. Method of radioactive labelling of blood cells and kit therefor
WO1993002652A2 (en) * 1991-08-01 1993-02-18 Hybritech Incorporated Modified haptens useful as imaging and therapeutic agents
US5686058A (en) * 1992-04-30 1997-11-11 Amersham International Plc Radiolabelled nucleotide formulations stored in an unfrozen state
CA2105402C (en) * 1992-04-30 2000-04-04 Roger M. Price Radiolabelled compound formulations
US5342926A (en) * 1993-06-08 1994-08-30 The Regents Of The University Of California Analogs of cytochalasin B as radiopharmaceuticals for nuclear imaging of trans-membrane glucose transport
RU2104035C1 (ru) * 1995-02-27 1998-02-10 Физико-энергетический институт Препарат, содержащий органическое соединение, меченное бета-радионуклидом
WO1997001520A1 (en) * 1995-06-28 1997-01-16 E.I. Du Pont De Nemours And Company Composition and method for stabilizing radiolabeled organic compounds
ATE314097T1 (de) 1996-10-28 2006-01-15 Amersham Health As Kontrastmittel
US5961955A (en) 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
HUP0101921A2 (hu) * 2001-05-10 2004-01-28 Izotóp Intézet Kft Radioaktívan jelzett nukleotido/ka/t tartalmazó preparátumok és eljárás azok előállítására
JP5139678B2 (ja) * 2003-07-24 2013-02-06 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 安定な放射性医薬品組成物およびその製法
US11474106B2 (en) 2015-07-08 2022-10-18 Lawrence Livermore National Security, Llc Methods for cytotoxic chemotherapy-based predictive assays
WO2018132766A1 (en) * 2017-01-12 2018-07-19 The Regents Of The University Of California Cytotoxic chemotherapy-based predictive assays for acute myeloid leukemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919095A (en) * 1973-07-30 1975-11-11 Mobil Oil Corp Organic compositions containing antioxidant and antiwear additives
US3876550A (en) * 1974-04-15 1975-04-08 Lubrizol Corp Lubricant compositions
US4358434A (en) * 1979-12-19 1982-11-09 New England Nuclear Corporation Method, composition and kit for stabilizing radiolabeled compounds
US4390517A (en) * 1979-12-19 1983-06-28 New England Nuclear Corporation Method, composition and kit for stabilizing radiolabeled compounds

Also Published As

Publication number Publication date
US4411881A (en) 1983-10-25
DE3324593C2 (de) 1986-10-23
FR2536998B1 (fr) 1988-01-22
GB2123412A (en) 1984-02-01
GB8316714D0 (en) 1983-07-20
CH655853A5 (de) 1986-05-30
DE3324593A1 (de) 1984-02-02
CA1205070A (en) 1986-05-27
JPS5924257A (ja) 1984-02-07
FR2536998A1 (fr) 1984-06-08
GB2123412B (en) 1986-03-05

Similar Documents

Publication Publication Date Title
JPH0211105B2 (enExample)
AU2016201367B2 (en) Stabilization of radiopharmaceutical compositions using ascorbic acid
EP0031121B1 (en) Method, composition and kit for stabilizing radiolabeled compounds
EP0785951B1 (en) Tc or re radiolabelled somatostatin analogs
IL107560A (en) Kit for making radiopharmaceutical preparations containing the Technium-M99 complex
JPS645256B2 (enExample)
BR112014003336B1 (pt) processo para a preparação de complexos de 68 ga, kit de reação e frasco para uso no referido processo
CN114206845A (zh) 锆络合物的合成方法
US20090005595A1 (en) Gentisic Acid for Stabilising 123-I Radiopharmaceuticals
US5738836A (en) Composition for stabilizing radiolabeled organic compounds
ES2629340T3 (es) Conjugados de N-alcoxiamida como agentes para obtención de imágenes
US20240350683A1 (en) Preparation of a ph-adjusted ascorbic acid solution
CN103841994B (zh) 适用于pet成像的氟化茋的制剂
Conway et al. PET studies of potential chemotherapeutic agents—X. Synthesis of “no-carrier-added”(11C)-HECNU: The hydroxyethyl analog of the chemotherapeutic agent BCNU
ES2320805T3 (es) Nanoparticulas radiomarcadas.
JP3967654B2 (ja) グアニジノ基を有する放射性遷移金属錯体
CA1198549A (en) Stabilization of radiolabeled organic compound
El-Sabagh et al. Preparation and Biodistribution of 99 m Tc-Trazodone as a Brain Imaging Probe
AU2010237040B9 (en) Stabilization of radiopharmaceutical compositions using ascorbic acid
Lamesa et al. 68Ga somatostatin analog radiolabelling: The radiopharmacist's point of view
Maina et al. Synthesis, radiochemistry and biological evaluation of technetium-99m complexes with 1, 8-diamine-3, 6-dithiaoctane (DDO) ligands