JPH0210836B2 - - Google Patents

Info

Publication number
JPH0210836B2
JPH0210836B2 JP56087985A JP8798581A JPH0210836B2 JP H0210836 B2 JPH0210836 B2 JP H0210836B2 JP 56087985 A JP56087985 A JP 56087985A JP 8798581 A JP8798581 A JP 8798581A JP H0210836 B2 JPH0210836 B2 JP H0210836B2
Authority
JP
Japan
Prior art keywords
vinblastine
deacetyl
ethyl
oil
tryptophanate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56087985A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5728094A (en
Inventor
Benowa Reon Torue Andore
Shiuapurasada Bushana Rao Kandeyukuri
Arufuretsudo Arufuonsu Anaaru Jan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of JPS5728094A publication Critical patent/JPS5728094A/ja
Publication of JPH0210836B2 publication Critical patent/JPH0210836B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP8798581A 1980-06-10 1981-06-08 N-(vinblastine-23-oyl)amino acid derivative Granted JPS5728094A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (fr) 1980-06-10 1980-06-10 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
JPS5728094A JPS5728094A (en) 1982-02-15
JPH0210836B2 true JPH0210836B2 (enExample) 1990-03-09

Family

ID=19729417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8798581A Granted JPS5728094A (en) 1980-06-10 1981-06-08 N-(vinblastine-23-oyl)amino acid derivative

Country Status (4)

Country Link
JP (1) JPS5728094A (enExample)
BE (1) BE889136A (enExample)
LU (1) LU82514A1 (enExample)
ZA (1) ZA813781B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant
WO2011103007A2 (en) * 2010-02-22 2011-08-25 The Scripps Research Institute 10'-fluorinated vinca alkaloids provide enhanced biological activity against mdr cancer cells

Also Published As

Publication number Publication date
LU82514A1 (fr) 1982-01-20
BE889136A (fr) 1981-12-09
ZA813781B (en) 1982-06-30
JPS5728094A (en) 1982-02-15

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