JPS5728094A - N-(vinblastine-23-oyl)amino acid derivative - Google Patents

N-(vinblastine-23-oyl)amino acid derivative

Info

Publication number
JPS5728094A
JPS5728094A JP8798581A JP8798581A JPS5728094A JP S5728094 A JPS5728094 A JP S5728094A JP 8798581 A JP8798581 A JP 8798581A JP 8798581 A JP8798581 A JP 8798581A JP S5728094 A JPS5728094 A JP S5728094A
Authority
JP
Japan
Prior art keywords
oyl
vinblastine
amino acid
acid derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8798581A
Other languages
Japanese (ja)
Other versions
JPH0210836B2 (en
Inventor
Benowa Reon Torue Andore
Shibuapurasada Bus Kandeyukuri
Arufuretsudo Arufuonsu A Jiyan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of JPS5728094A publication Critical patent/JPS5728094A/en
Publication of JPH0210836B2 publication Critical patent/JPH0210836B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP8798581A 1980-06-10 1981-06-08 N-(vinblastine-23-oyl)amino acid derivative Granted JPS5728094A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (en) 1980-06-10 1980-06-10 N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
JPS5728094A true JPS5728094A (en) 1982-02-15
JPH0210836B2 JPH0210836B2 (en) 1990-03-09

Family

ID=19729417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8798581A Granted JPS5728094A (en) 1980-06-10 1981-06-08 N-(vinblastine-23-oyl)amino acid derivative

Country Status (4)

Country Link
JP (1) JPS5728094A (en)
BE (1) BE889136A (en)
LU (1) LU82514A1 (en)
ZA (1) ZA813781B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62175486A (en) * 1986-01-13 1987-08-01 ラ　レジョン　ワロン Vinblastine derivative and its production
JP2013520499A (en) * 2010-02-22 2013-06-06 ザ スクリプス リサーチ インスティチュート 10'-fluorinated vinca alkaloids that provide enhanced biological activity against MDR cancer cells

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62175486A (en) * 1986-01-13 1987-08-01 ラ　レジョン　ワロン Vinblastine derivative and its production
JPH075608B2 (en) * 1986-01-13 1995-01-25 イ−ル−セルタ−ク ソシエテ アノニム Vinblastine derivative
JP2013520499A (en) * 2010-02-22 2013-06-06 ザ スクリプス リサーチ インスティチュート 10'-fluorinated vinca alkaloids that provide enhanced biological activity against MDR cancer cells

Also Published As

Publication number Publication date
JPH0210836B2 (en) 1990-03-09
ZA813781B (en) 1982-06-30
LU82514A1 (en) 1982-01-20
BE889136A (en) 1981-12-09

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