JPH01308276A - ベンゾ[b]チオフェン誘導体 - Google Patents

ベンゾ[b]チオフェン誘導体

Info

Publication number
JPH01308276A
JPH01308276A JP1062328A JP6232889A JPH01308276A JP H01308276 A JPH01308276 A JP H01308276A JP 1062328 A JP1062328 A JP 1062328A JP 6232889 A JP6232889 A JP 6232889A JP H01308276 A JPH01308276 A JP H01308276A
Authority
JP
Japan
Prior art keywords
lower alkyl
substituted
halogen
unsubstituted
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1062328A
Other languages
English (en)
Japanese (ja)
Inventor
Pier G Ferrini
ペール ジョルジオ フェリーニ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPH01308276A publication Critical patent/JPH01308276A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
JP1062328A 1988-03-16 1989-03-16 ベンゾ[b]チオフェン誘導体 Pending JPH01308276A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH00998/88-8 1988-03-16
CH99888 1988-03-16

Publications (1)

Publication Number Publication Date
JPH01308276A true JPH01308276A (ja) 1989-12-12

Family

ID=4200067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1062328A Pending JPH01308276A (ja) 1988-03-16 1989-03-16 ベンゾ[b]チオフェン誘導体

Country Status (10)

Country Link
US (2) US5051421A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0336886B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH01308276A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE79876T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE58902111D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK126989A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2052059T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3005857T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE890828L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT90002B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436246A (en) * 1992-09-17 1995-07-25 Merrell Dow Pharmaceuticals Inc. Serotonin receptor agents
US5789436A (en) * 1994-04-11 1998-08-04 Chugai Seiyak Kabushiki Kaisha 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene
FR2793245B1 (fr) * 1999-05-05 2002-10-11 Adir Nouveaux composes pyridiniques ou piperidiniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE339235B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1965-06-01 1971-10-04 Haessle Ab
US4514415A (en) * 1981-10-28 1985-04-30 Ciba Geigy Corporation Benzofuran-2(3H)-ones used as anti-inflammatory agents
US4663344A (en) * 1985-03-11 1987-05-05 Merck & Co., Inc. Anti-inflammatory and analgesic 3-hydroxybenzo[b]thiophene derivatives, compositions, and method of use therefor

Also Published As

Publication number Publication date
GR3005857T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-07
PT90002A (pt) 1989-11-10
EP0336886B1 (de) 1992-08-26
DK126989D0 (da) 1989-03-15
US5051421A (en) 1991-09-24
ATE79876T1 (de) 1992-09-15
IE890828L (en) 1989-09-16
EP0336886A1 (de) 1989-10-11
US5147889A (en) 1992-09-15
DK126989A (da) 1989-09-17
DE58902111D1 (de) 1992-10-01
PT90002B (pt) 1994-06-30
ES2052059T3 (es) 1994-07-01

Similar Documents

Publication Publication Date Title
KR890002758B1 (ko) 헤테로시클릭 옥소프탈라지닐 아세트산 및 그의 제조 방법
JP3123562B2 (ja) ピラゾロピリジン化合物およびその製造法
PL172035B1 (pl) Pochodne sulfonamidowe antagonisty endoteliny PL PL PL PL PL
JPS6322079A (ja) 新規なスチリルピラゾ−ル、イソキサゾ−ルおよびその類似体
JPH06501682A (ja) 複素環化合物及びそれらの製造及び用途
HK7289A (en) 2-arylimidazopyridines
EP0160408B1 (en) Benzothiophenes, their production and use, and compositions containing them
EP0295049A2 (en) Thiophene sulfonamide antiglaucoma agents
JPH01104038A (ja) アラルキルアミノアルコキシフェニル誘導体、その製法およびそれを含有する組成物
GB1561504A (en) Thienopyridine derivatives and their application
US4654344A (en) Pharmaceutical compositions for treating ulcers containing 2-aryltetraazaindenes
JPS609716B2 (ja) 1,2―ベンズインチアゾリン―3―オン類、それらの製造法および医薬としての使用
JPH01308276A (ja) ベンゾ[b]チオフェン誘導体
JPH02172973A (ja) テトラリン誘導体
EP0077083B1 (fr) Nouveaux dérivés de la thioformamide, leur préparation et les médicaments qui les contiennent
JPS63258854A (ja) カルボキシスチレン誘導体およびそれを有効成分とする薬剤
US5100911A (en) Thienyloxyalkylamine derivatives, process for their preparation and medicaments containing them
JPH0327363A (ja) チオウラシル誘導体
US3929833A (en) Organic compounds
CH628014A5 (en) Gamma-aryl-gamma-oxoisovaleric acids having antiphlogistic and antalgic properties
SU1491340A3 (ru) Способ получени производных спартеина или их фармакологически приемлемых кислотно-аддитивных солей
US3795681A (en) Aminothiophene-carboxylic acid esters
EP0382628B1 (fr) Dérivés aminoalkoxyphényle, leur procédé de préparation ainsi que les compositions en contenant
GB2096143A (en) Imidazo(1,2-a)quinoline derivatives
US4137323A (en) Organic compounds