JPH01216908A - Cosmetic - Google Patents

Abstract

PURPOSE:To obtain a cosmetic having excellent oxidation stability, by compounding a fatty acid having specific carbon number and unsaturated bond number, an antioxidant such as dibutylhydroxytoluene, amino acid, etc., and aliphatic polybasic oxyacid, etc. CONSTITUTION:The objective cosmetic is produced by compounding (A) 0.1-10wt.% of a 18-22C free fatty acid having >=2 unsaturated bonds, its salt or ester (e.g., linoleic acid), (B) 0.001-5.0wt.% of an antioxidant such as dibutylhydroxytoluene, erythorbic acid, propyl gallate, sage extract, etc., (C) amino acid and/or its ester (e.g., glycine or aspartic acid) and (D) a compound selected from an aliphatic polybasic oxyacid, its salt or monoester and a carboxyvinyl polymer. The cosmetic has excellent oxidation stability and exhibits and required effect over a long period.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present invention relates to free fatty acids having 18 to 22 carbon atoms and 2 or more unsaturated bonds in the molecular structure, their salts, or esters with monohydric or dihydric alcohols. Concerning cosmetics that are stably formulated.

Conventional technologies and issues - Fatty acids with 18 to 22 carbon atoms and two or more unsaturated bonds in their molecular structure (hereinafter referred to as essential fatty acids), such as linoleic acid and lylunic acid, are essential substances for maintaining human health. be. Such fatty acid deficiency symptoms are known to include dry, scaly skin, frizzy hair, and widespread erythema.

On the other hand, the efficacy and effects when such essential fatty acids are blended into cosmetics are known to include moisturizing effect, tyrosinase activity inhibiting effect, and hair-nourishing effect. However, these essential fatty acids are extremely unstable to air oxidation, and are often accompanied by discoloration and odor when incorporated into cosmetics.

Therefore, ascorbic acid derivatives, tocopherols, and the like have conventionally been used as antioxidants for such fatty acids. However, the effect is not necessarily sufficient, and discoloration and odor generation due to deterioration of the antioxidant itself also poses problems.

An object of the present invention is to provide a cosmetic composition containing an essential fatty acid, its salt or ester, and having excellent oxidative stability.

Means for Solving the Problems The present invention provides (a) a free fatty acid having 18 to 22 carbon atoms and 2 or more unsaturated bonds in its molecular structure, a salt thereof, or an ester with a monohydric or dihydric alcohol, and ( b) Dibutylhydroxytoluene, butylhydroxyanisole, erythorbic acid, sodium erythorbate, nordihydroguaiaretic acid, propyl gallate,
one or more antioxidants selected from the group consisting of sage extract, rosemary extract, and mace extract; (C) an amino acid and/or its ester; (d)
The present invention provides a cosmetic containing one or more compounds selected from the group consisting of lucid aliphatic oxine polybasic acids, salts thereof, monoesters, and carboxyvinyl polymers.

Fatty acids having 18 to 22 carbon atoms and having 2 or more unsaturated bonds in the molecular structure, such as linoleic acid and lylunic acid, which are blended into the composition of the present invention, are contained in vegetable oils and animal fats.

Typical free fatty acids with 18 to 22 carbon atoms and 2 or more unsaturated bonds in the molecular structure that are incorporated into the cosmetics of the present invention include linoleic acid, linoleaidic acid, α-lylinic acid, and γ-linoleic acid. -lylunic acid, dihomo-7-lylunic acid, arachidonic acid, eicosapentaenoic acid, etc., and one or more of these may be used.

In addition, as salts of these free fatty acids, sodium salts,
Examples include metal salts such as potassium salts, amino acid salts such as arginine salts and lysine salts, and amine salts such as triethanolamine salts and monoethanolamine salts.

Furthermore, as the alkyl ester of the free fatty acid,
Esters with monohydric alcohols such as methanol, ethanol, isopropyl alcohol, ethylene glycol,
Examples include esters with dihydric alcohols such as propylene glycol and 1,3-butylene glycol.

The content of these free fatty acids and their salts or esters in cosmetics is preferably 0.1-10% by weight. If the amount is less than 0.1% by weight, there is no effect, while if it exceeds 10% by weight, the irritation is strong.

On the other hand, the antioxidants to be incorporated into the cosmetics of the present invention include dibutylhydroxytoluene, butylhydroxyanisole, erythorbic acid, sodium erythorbate,
Examples include nordihydroguaiaretic acid, propyl gallate, sage extract, rosemary extract, and mace extract.

The amount of these antioxidants in cosmetics is o, o
ot~5.0% by weight. If the amount is less than this, there will be no effect, while if it is more than this, the deterioration of the essential fatty acid, its salt or ester may be accelerated.

The effects of these antioxidants are increased by using them in combination with amino acids or esters thereof.

Next, typical examples of the amino acids to be incorporated into the cosmetics of the present invention include glycine, alanine, valine, leucine, isoleucine, serine, threon, lysine, asparagine, aspartic acid, glutamine, glutamic acid,
Phenylalanine, tyrosine, proline, arginine,
Cystine, histidine, etc. are mentioned, and the ester thereof is preferably an ester with a monohydric alcohol. These may be used alone or in combination.

The cosmetic composition of the present invention further contains an aliphatic oxypolybasic acid, a salt or monoester thereof, and a carboxyvinyl polymer alone or in combination.

By blending these, the effects of the antioxidants are synergistically increased. As the aliphatic oxypolybasic acid,
Examples include citric acid, gluconic acid, tartaric acid, and malic acid.

Next, the results of testing the stability of the cosmetic composition of the present invention will be shown.

[Stability test (1)] Ingredients Part by weight Linoleic acid 1.0P OE (60)
Hydrogenated castor oil 1.0 ethanol
! 0.0 antioxidant
1.3-Butylene glycol listed in Table 1
5.01.0M NaOH aqueous solution pH adjustment
(pH 7.0) Ion-exchanged water Remainder (JR method) Linoleic acid and POE (60) hydrogenated castor oil were dissolved in ethanol, and 1.3-butylene glycol was dissolved in ion-exchanged water.

Next, dibdelhydroxytoluene (BHT) and citric acid were dissolved in the ethanol phase, and thi-threonine, L-instin, and carboxyvinyl polymer were dissolved in the aqueous phase. Then, the ethanol phase was added to the aqueous phase and mixed and stirred to solubilize or gel.
An aqueous solution was added to adjust the pH to 7 and 0. This is 40℃
The sample was left in a constant temperature room for 3 months, and the residual rate of linoleic acid was determined by high performance liquid chromatography.

Table 1 [Stability test (2)] Ingredients Part by weight Linoleic acid 1.0BHT
0.05P OE (60) Hydrogenated castor oil 1.0 Ethanol
5,0 Amino acid or amino acid ester Carboxyvinyl polymer listed in Table 2 0
．． 8KOH0.5 Ion-exchanged water, remainder l manufacturing method) Linoleic acid, BHT, POE (60) Hydrogenated castor oil,
The amino acid ester was dissolved in ethanol, and the carboxyvinyl polymer, amino acid, and KOH were dissolved in ion-exchanged water. Then, the ethanol phase was added to the aqueous phase and mixed and stirred to obtain a gel composition.

This was left in a constant temperature room at 40°C for 3 months, and the residual rate of linoleic acid was determined by high performance liquid chromatography.

Table 2 The cosmetics of the present invention are manufactured in the form of lotions, cosmetic oils, creams, milky lotions, packs, powders, etc. by known methods.

Further, the cosmetic composition of the present invention may contain any known ingredients as appropriate, depending on the type thereof, within a range that does not impair performance.

Kantane ■ Next, the present invention will be explained in more detail with reference to Examples.

Example 1 (lotion) Ingredients Heavy industry % linoleic acid 0.5 dibutylhydroxytoluene 0.05 citric acid
005 Polyoxyethylene hydrogenated castor oil
10 (60E, O,) Methyl paraoxybenzoate 0.05 Ethanol 15.0 Glycerin
8.0 Potassium hydroxide
0.15 Sodium Tartrate
0.03-glycine 0.05
L-serine 0505L-cystine o, oot fragrance
0.1 Purified water Dissolve glycerin, potassium hydroxide, sodium tartrate, L-glycine, L-serine, and cystine in the remaining purified water. Separately,
Ethanol, linoleic acid, dibutylhydroxytoluene, citric acid, polyoxyethylene hydrogenated castor oil (60E
, O,), methylparaben, and fragrance were dissolved, added to the purified aqueous solution, solubilized, and filtered to obtain a lotion.

Example 2 (Aqueous gel) Ingredients Weight % α-lylunic acid 1.0 Dibutylhydroxytoluene 0.05 Polyoxyethylene hydrogenated castor oil 1.5 (60E, O,) L-Histidine ethyl ester 0.01 Paraoxybenzoic acid Methyl 0.05 fragrance
0.1 Ethanol 5.0 Carboxyvinyl polymer 1. OL-valine
0.05DL-phenylalanine
0.05L-arginine 0
．． Potassium monohydroxide 0.5 Purified water Carboxyvinyl polymer, L-valine, DL-phenylalanine, L-arginine, and potassium hydroxide were dissolved in the remaining purified water. Separately, 'α-lylunic acid, dibutylhydroxytoluene, polyoxyethylene hydrogenated castor oil (60E, O
,), dissolve histidine ethyl ester, methylparaben, and fragrance, add to the purified aqueous solution, mix and stir,
An aqueous gel cosmetic was obtained.

Example 3 (Cream) (Ingredient (A)) Ingredients Weight % γ-Lilunic Acid 2,0 Saran Beeswax
40 cetanol
2.0 Stearic acid 1.0 Ethyl linoleate 5.0 Lanolin
2.0 liquid paraffin
9.0 Self-emulsifying glyceryl monostearate 30 mo I poly(stearic acid) polyethylene solpitan (20E, O,)
1.5 Propyl paraoxybenzoate 0.1 Dibutylhydroxytoluene 0.05 (Component (B)
)) Ingredients Weight% citric acid
0.05 malic acid
0.05 carboxyvinyl polymer 0.1 methyl paraoxybenzoate
0.2 Propylene glycol 5. O.D.
-Alanine 0. IL-asparagine 0.05L-histidine
0.01L-isoleucine
0.5 Fragrance 0.2 Purified water Dissolve the remaining component (A) by heating and maintain at 80°C.

Separately, component (B) excluding fragrance is dissolved by heating and maintained at 80°C, and component (A) is added thereto with stirring and thoroughly mixed. Cool while stirring further, add flavoring,
It was further cooled to obtain cream.

Example 4 (Emulsion) (Component (A)) Ingredients Weight% Ethyl arachidonate 0.2 Isopropyl linoleate 2.0 Liquid paraffin
5.0 Vaseline 2.
0 Beeswax l・0 Sorbitan sesquioleate 20 Butylhydroxytoluene 005 Butylhydroxyanisole
0.05 (Component (B)) Ether (20E, O,) Ethyl paraoxene benzoate 02 Propylene glycol 5.0 Carboxyvinyl polymer 05 Potassium hydroxide
0.5DL-Threonine 0.05L
-Glutamine 0.05L-Instin 0.001Sodium citrate 0.05Drink 0.
2. Purified water Dissolve the remaining component (A) by heating at 80°C, add to the separately heated (80°C) dissolved component (B) excluding the fragrance, and mix thoroughly with stirring. Next, the mixture was cooled while stirring, perfume was added, and the mixture was further cooled to obtain a milky lotion.

Example 5 (Pack) Ingredients Weight % Rhinoelaidic acid 3.0 Vinyl acetate-styrene copolymer 10.0 Polyvinyl alcohol
1O10 sorbit 5.
0 Titanium oxide 8.0 Power/Olin 7.0 Isoprobyl citrate 0. Ol dibutylhydroxytoluene 0.05 ethanol
5.0 Methyl oxybenzoate
0.2 Proline 0
．． 1 L-Glutamic acid 0.01 Flavor 2.0 Purified water The remainder Linoelaidic acid, isopropyl citrate and dibutylhydroxytoluene are dissolved in ethanol. Add this to vinyl.
Add styrene copolymer, polyvinyl alcohol, sorbitol, titanium oxide, and kaolin to a homogeneous mixture.

To this, a solution in which methylparaben, proline, and L-glutamic acid were uniformly dissolved in purified water was added and mixed uniformly to obtain a bag.

Effects of the Invention According to the cosmetic composition of the present invention, essential fatty acids, their salts and esters are stably blended, and the desired effects are maintained over a long period of time.

Patent developer Sunstar Co., Ltd.

Claims (2)

[Claims] (1) (a) Free fatty acids with 18 to 22 carbon atoms and 2 or more unsaturated bonds in the molecular structure, their salts, or esters with monohydric or dihydric alcohols, and (b) dibutylhydroxytoluene, butyl Hydroxyanisole, erythorbic acid, sodium erythorbate, nordihydroguaiaretic acid, propyl gallate,
one or more antioxidants selected from the group consisting of sage extract, rosemary extract, and mace extract; (c) amino acids and/or esters thereof; (d) aliphatic oxypolybasic acids; A cosmetic containing one or more compounds selected from the group consisting of salts, monoesters, and carboxyvinyl polymers. (2) The cosmetic according to item (1) above, wherein the aliphatic oxypolybasic acid is gluconic acid, citric acid, tartaric acid, or malic acid.