JPH01149723A - 骨芽細胞活性化剤 - Google Patents

骨芽細胞活性化剤

Info

Publication number
JPH01149723A
JPH01149723A JP62308982A JP30898287A JPH01149723A JP H01149723 A JPH01149723 A JP H01149723A JP 62308982 A JP62308982 A JP 62308982A JP 30898287 A JP30898287 A JP 30898287A JP H01149723 A JPH01149723 A JP H01149723A
Authority
JP
Japan
Prior art keywords
compound
formula
activator
present
osteoblast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62308982A
Other languages
English (en)
Japanese (ja)
Inventor
Hajime Orimo
折茂　肇
Hiroshi Sato
博 佐藤
Kohei Miyao
興平 宮尾
Norihiro Kakimoto
柿本　紀博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asai Germanium Research Institute
Original Assignee
Asai Germanium Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asai Germanium Research Institute filed Critical Asai Germanium Research Institute
Priority to JP62308982A priority Critical patent/JPH01149723A/ja
Priority to US07/276,666 priority patent/US5002968A/en
Priority to CH4425/88A priority patent/CH675725A5/fr
Priority to DE3840744A priority patent/DE3840744C2/de
Priority to GB8828208A priority patent/GB2213059B/en
Priority to CA000584964A priority patent/CA1322719C/en
Priority to IT8822885A priority patent/IT1227884B/it
Priority to FR8816077A priority patent/FR2624120B1/fr
Publication of JPH01149723A publication Critical patent/JPH01149723A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/30—Germanium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP62308982A 1987-12-07 1987-12-07 骨芽細胞活性化剤 Pending JPH01149723A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP62308982A JPH01149723A (ja) 1987-12-07 1987-12-07 骨芽細胞活性化剤
US07/276,666 US5002968A (en) 1987-12-07 1988-11-28 Activator for osteoblasts
CH4425/88A CH675725A5 (enExample) 1987-12-07 1988-11-29
DE3840744A DE3840744C2 (de) 1987-12-07 1988-12-02 Aktivator für Osteoblasten
GB8828208A GB2213059B (en) 1987-12-07 1988-12-02 Osteoblast activator comprising a basic salt of an organogermanium compound
CA000584964A CA1322719C (en) 1987-12-07 1988-12-05 Activator for osteoblast
IT8822885A IT1227884B (it) 1987-12-07 1988-12-06 Attivatore per osteoblasto
FR8816077A FR2624120B1 (fr) 1987-12-07 1988-12-07 Nouveaux sels organogermaniques utiles comme medicaments notamment comme activateurs des osteoblastes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62308982A JPH01149723A (ja) 1987-12-07 1987-12-07 骨芽細胞活性化剤

Publications (1)

Publication Number Publication Date
JPH01149723A true JPH01149723A (ja) 1989-06-12

Family

ID=17987535

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62308982A Pending JPH01149723A (ja) 1987-12-07 1987-12-07 骨芽細胞活性化剤

Country Status (8)

Country Link
US (1) US5002968A (enExample)
JP (1) JPH01149723A (enExample)
CA (1) CA1322719C (enExample)
CH (1) CH675725A5 (enExample)
DE (1) DE3840744C2 (enExample)
FR (1) FR2624120B1 (enExample)
GB (1) GB2213059B (enExample)
IT (1) IT1227884B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU635045B2 (en) * 1989-07-20 1993-03-11 Asai Germanium Research Institute Co., Ltd Agent for preventing and treating opacity of lens
JPH05255130A (ja) * 1992-03-16 1993-10-05 Asai Gerumaniumu Kenkyusho:Kk メイラード反応抑制改善剤
AU2003230850A1 (en) * 2002-04-10 2003-10-27 Surromed, Inc. Propagermanium for treating myeloma bone disease and other bone disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185715A (ja) * 1984-03-05 1985-09-21 Teijin Ltd 骨形成促進剤
JPS61145116A (ja) * 1984-12-18 1986-07-02 Asai Gerumaniumu Kenkyusho:Kk オステオポロ−ジス治療剤
JPS62252794A (ja) * 1986-04-09 1987-11-04 Asai Gerumaniumu Kenkyusho:Kk 有機ゲルマニウム化合物及びそれを含む薬剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA970277A (en) * 1972-05-25 1975-07-01 Kazuhiko Asai Organo germanium sesquioxide composition for treating hypertension or hypotonia
JPS55122717A (en) * 1979-03-15 1980-09-20 Asai Gerumaniumu Kenkyusho:Kk Interferon inducer
JPS63107920A (ja) * 1986-06-18 1988-05-12 Asai Gerumaniumu Kenkyusho:Kk 骨芽細胞活性化剤
JP2698870B2 (ja) * 1987-10-29 1998-01-19 株式会社浅井ゲルマニウム研究所 シクロスポリンの投与による腎毒性の軽減剤
CA1314210C (en) * 1987-10-29 1993-03-09 Norihiro Kakimoto Agent for improving reduced functions of organs caused by inhibited blood circulation
JPH01117801A (ja) * 1987-10-29 1989-05-10 Asai Gerumaniumu Kenkyusho:Kk 分離臓器洗浄保存液

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60185715A (ja) * 1984-03-05 1985-09-21 Teijin Ltd 骨形成促進剤
JPS61145116A (ja) * 1984-12-18 1986-07-02 Asai Gerumaniumu Kenkyusho:Kk オステオポロ−ジス治療剤
JPS62252794A (ja) * 1986-04-09 1987-11-04 Asai Gerumaniumu Kenkyusho:Kk 有機ゲルマニウム化合物及びそれを含む薬剤

Also Published As

Publication number Publication date
CH675725A5 (enExample) 1990-10-31
DE3840744C2 (de) 1994-09-08
DE3840744A1 (de) 1989-06-15
GB2213059B (en) 1991-07-31
GB2213059A (en) 1989-08-09
GB8828208D0 (en) 1989-01-05
IT8822885A0 (it) 1988-12-06
FR2624120A1 (fr) 1989-06-09
IT1227884B (it) 1991-05-14
CA1322719C (en) 1993-10-05
FR2624120B1 (fr) 1994-02-25
US5002968A (en) 1991-03-26

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