JP7823036B2 - アセトアミド－フェニルテトラゾール誘導体およびその使用方法 - Google Patents
アセトアミド－フェニルテトラゾール誘導体およびその使用方法Info
- Publication number
- JP7823036B2 JP7823036B2 JP2023521299A JP2023521299A JP7823036B2 JP 7823036 B2 JP7823036 B2 JP 7823036B2 JP 2023521299 A JP2023521299 A JP 2023521299A JP 2023521299 A JP2023521299 A JP 2023521299A JP 7823036 B2 JP7823036 B2 JP 7823036B2
- Authority
- JP
- Japan
- Prior art keywords
- heteroatoms selected
- membered
- substituted
- alkyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063088788P | 2020-10-07 | 2020-10-07 | |
| US63/088,788 | 2020-10-07 | ||
| PCT/US2021/053937 WO2022076663A1 (en) | 2020-10-07 | 2021-10-07 | Acetamido-phenyltetrazole derivatives and methods of using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023544615A JP2023544615A (ja) | 2023-10-24 |
| JP2023544615A5 JP2023544615A5 (https=) | 2024-10-04 |
| JP7823036B2 true JP7823036B2 (ja) | 2026-03-03 |
Family
ID=78483546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023521299A Active JP7823036B2 (ja) | 2020-10-07 | 2021-10-07 | アセトアミド－フェニルテトラゾール誘導体およびその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11739089B2 (https=) |
| EP (1) | EP4225747A1 (https=) |
| JP (1) | JP7823036B2 (https=) |
| KR (1) | KR20230104151A (https=) |
| CN (1) | CN116964044B (https=) |
| AU (1) | AU2021358074A1 (https=) |
| CA (1) | CA3194694A1 (https=) |
| IL (1) | IL301516A (https=) |
| MX (1) | MX2023003933A (https=) |
| TW (1) | TWI900672B (https=) |
| WO (1) | WO2022076663A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10118890B2 (en) | 2014-10-10 | 2018-11-06 | The Research Foundation For The State University Of New York | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration |
| CN110312130B (zh) * | 2019-06-25 | 2021-10-15 | 浙江大华技术股份有限公司 | 基于三角模式的帧间预测、视频编码方法及设备 |
| TWI900672B (zh) | 2020-10-07 | 2025-10-11 | 香港商希華醫藥有限公司 | 乙醯胺基－苯基四唑衍生物及其使用方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013517267A (ja) | 2010-01-15 | 2013-05-16 | ハンミ・サイエンス・カンパニー・リミテッド | テトラゾールメタンスルホン酸塩の製造方法及びそれに用いられる新規化合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5663179A (en) | 1992-07-10 | 1997-09-02 | Laboratoires Glaxo Sa | Certain isoquinoline derivatives having anti-tumor properties |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| GB9717576D0 (en) | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| KR100557093B1 (ko) * | 2003-10-07 | 2006-03-03 | 한미약품 주식회사 | 다약제 내성 저해 활성을 갖는 테트라졸 유도체 및 그의제조방법 |
| KR101986683B1 (ko) | 2012-12-13 | 2019-06-10 | 한미약품 주식회사 | 테트라졸 유도체를 활성 성분으로 포함하는 용해도가 개선된 고체 분산체 |
| WO2015152433A1 (en) | 2014-03-31 | 2015-10-08 | Hanmi Pharm. Co., Ltd. | Amorphous solid dispersion comprising paclitaxel, tablet comprising the same, and method for preparing the same |
| KR102293907B1 (ko) | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | 이리노테칸 함유 경구용 고형제제 및 그 제조방법 |
| TWI838700B (zh) | 2015-09-30 | 2024-04-11 | 香港商慧源香港創新有限公司 | 口服紫杉烷組合物及方法 |
| TWI833710B (zh) | 2017-10-06 | 2024-03-01 | 香港商慧源香港創新有限公司 | 高單位含量口服型紫杉烷組合物及方法 |
| TWI900672B (zh) | 2020-10-07 | 2025-10-11 | 香港商希華醫藥有限公司 | 乙醯胺基－苯基四唑衍生物及其使用方法 |
-
2021
- 2021-10-07 TW TW110137339A patent/TWI900672B/zh active
- 2021-10-07 US US17/495,935 patent/US11739089B2/en active Active
- 2021-10-07 AU AU2021358074A patent/AU2021358074A1/en active Pending
- 2021-10-07 MX MX2023003933A patent/MX2023003933A/es unknown
- 2021-10-07 CA CA3194694A patent/CA3194694A1/en active Pending
- 2021-10-07 WO PCT/US2021/053937 patent/WO2022076663A1/en not_active Ceased
- 2021-10-07 KR KR1020237015140A patent/KR20230104151A/ko active Pending
- 2021-10-07 EP EP21801761.4A patent/EP4225747A1/en active Pending
- 2021-10-07 JP JP2023521299A patent/JP7823036B2/ja active Active
- 2021-10-07 CN CN202180079852.2A patent/CN116964044B/zh active Active
- 2021-10-07 IL IL301516A patent/IL301516A/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013517267A (ja) | 2010-01-15 | 2013-05-16 | ハンミ・サイエンス・カンパニー・リミテッド | テトラゾールメタンスルホン酸塩の製造方法及びそれに用いられる新規化合物 |
Non-Patent Citations (3)
| Title |
|---|
| Bioconjugate Chemistry，2014年05月07日，Vol.25, No.6，p.1137-1142 |
| In Silico Pharmacology，2021年01月03日，Vol.9(1):6，p.1-7，https://doi.org/10.1007//s40203-020-00066-7 |
| RAPID COMMUNICATIONS IN MASS SPECTROMETRY，2006年03月04日，Vol.20，p.1457-1462 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230104151A (ko) | 2023-07-07 |
| MX2023003933A (es) | 2023-07-05 |
| EP4225747A1 (en) | 2023-08-16 |
| US11739089B2 (en) | 2023-08-29 |
| WO2022076663A1 (en) | 2022-04-14 |
| CN116964044A (zh) | 2023-10-27 |
| IL301516A (en) | 2023-05-01 |
| AU2021358074A1 (en) | 2023-04-27 |
| CA3194694A1 (en) | 2022-04-14 |
| JP2023544615A (ja) | 2023-10-24 |
| TW202233593A (zh) | 2022-09-01 |
| TWI900672B (zh) | 2025-10-11 |
| CN116964044B (zh) | 2026-03-06 |
| US20220106312A1 (en) | 2022-04-07 |
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