JP7763018B1 - プロテオグリカンの製造方法 - Google Patents

プロテオグリカンの製造方法

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Publication number
JP7763018B1
JP7763018B1 JP2025505624A JP2025505624A JP7763018B1 JP 7763018 B1 JP7763018 B1 JP 7763018B1 JP 2025505624 A JP2025505624 A JP 2025505624A JP 2025505624 A JP2025505624 A JP 2025505624A JP 7763018 B1 JP7763018 B1 JP 7763018B1
Authority
JP
Japan
Prior art keywords
aqueous solution
alcohol
proteoglycan
salt
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2025505624A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2025163949A1 (https=
JPWO2025163949A5 (https=
Inventor
竜哉 和田
隼多 入谷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon Pharmaceutical Co Ltd
Original Assignee
Nihon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Pharmaceutical Co Ltd filed Critical Nihon Pharmaceutical Co Ltd
Publication of JPWO2025163949A1 publication Critical patent/JPWO2025163949A1/ja
Application granted granted Critical
Publication of JP7763018B1 publication Critical patent/JP7763018B1/ja
Publication of JPWO2025163949A5 publication Critical patent/JPWO2025163949A5/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09H—PREPARATION OF GLUE OR GELATINE
    • C09H3/00—Isolation of glue or gelatine from raw materials, e.g. by extracting, by heating
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
JP2025505624A 2024-01-29 2024-08-22 プロテオグリカンの製造方法 Active JP7763018B1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2024011110 2024-01-29
JP2024011110 2024-01-29
PCT/JP2024/029854 WO2025163949A1 (ja) 2024-01-29 2024-08-22 プロテオグリカンの製造方法

Publications (3)

Publication Number Publication Date
JPWO2025163949A1 JPWO2025163949A1 (https=) 2025-08-07
JP7763018B1 true JP7763018B1 (ja) 2025-10-31
JPWO2025163949A5 JPWO2025163949A5 (https=) 2026-01-06

Family

ID=96589836

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025505624A Active JP7763018B1 (ja) 2024-01-29 2024-08-22 プロテオグリカンの製造方法

Country Status (4)

Country Link
JP (1) JP7763018B1 (https=)
KR (1) KR20250120981A (https=)
CN (1) CN120769920A (https=)
WO (1) WO2025163949A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010124811A (ja) * 2008-12-01 2010-06-10 Daimatsu:Kk グリコサミノグリカンの減容抽出方法およびプロテオグリカン含有沈殿生成方法
JP2012236776A (ja) * 2011-05-09 2012-12-06 Institute Glycosmo Co Ltd プロテオグリカンの製造方法
JP2017173225A (ja) * 2016-03-25 2017-09-28 日本薬品株式会社 コンドロイチン硫酸プロテオグリカン及びコンドロイチン硫酸グリコサミノグリカンの分別・定量方法
CN110627863A (zh) * 2019-10-09 2019-12-31 广东丸美生物技术股份有限公司 蛋白多糖提取方法、提取物及其应用和化妆品
JP2020063214A (ja) * 2018-10-18 2020-04-23 国立大学法人 和歌山大学 プロテオグリカン及び／又はグリコサミノグリカンの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001172296A (ja) 1999-10-07 2001-06-26 Japan Science & Technology Corp 軟骨型プロテオグリカンの精製方法
JP3731150B2 (ja) 2000-08-22 2006-01-05 株式会社角弘 軟骨型プロテオグリカンの精製方法
JP4219974B2 (ja) 2006-02-14 2009-02-04 財団法人釧路根室圏産業技術振興センター プロテオグリカンの製造方法
JP6006545B2 (ja) 2012-06-27 2016-10-12 日本薬品株式会社 プロテオグリカンの製造方法
JP7295572B2 (ja) 2019-02-08 2023-06-21 一丸ファルコス株式会社 プロテオグリカンの製造方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010124811A (ja) * 2008-12-01 2010-06-10 Daimatsu:Kk グリコサミノグリカンの減容抽出方法およびプロテオグリカン含有沈殿生成方法
JP2012236776A (ja) * 2011-05-09 2012-12-06 Institute Glycosmo Co Ltd プロテオグリカンの製造方法
JP2017173225A (ja) * 2016-03-25 2017-09-28 日本薬品株式会社 コンドロイチン硫酸プロテオグリカン及びコンドロイチン硫酸グリコサミノグリカンの分別・定量方法
JP2020063214A (ja) * 2018-10-18 2020-04-23 国立大学法人 和歌山大学 プロテオグリカン及び／又はグリコサミノグリカンの製造方法
CN110627863A (zh) * 2019-10-09 2019-12-31 广东丸美生物技术股份有限公司 蛋白多糖提取方法、提取物及其应用和化妆品

Also Published As

Publication number Publication date
KR20250120981A (ko) 2025-08-11
JPWO2025163949A1 (https=) 2025-08-07
CN120769920A (zh) 2025-10-10
WO2025163949A1 (ja) 2025-08-07

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