JP7690211B2 - Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 - Google Patents
Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 Download PDFInfo
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- JP7690211B2 JP7690211B2 JP2022541951A JP2022541951A JP7690211B2 JP 7690211 B2 JP7690211 B2 JP 7690211B2 JP 2022541951 A JP2022541951 A JP 2022541951A JP 2022541951 A JP2022541951 A JP 2022541951A JP 7690211 B2 JP7690211 B2 JP 7690211B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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- A—HUMAN NECESSITIES
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- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- A—HUMAN NECESSITIES
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062958563P | 2020-01-08 | 2020-01-08 | |
| US62/958,563 | 2020-01-08 | ||
| PCT/US2021/012510 WO2021142127A1 (en) | 2020-01-08 | 2021-01-07 | A method of engineering natural killer cells to target cd70-positive tumors |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023509766A JP2023509766A (ja) | 2023-03-09 |
| JP2023509766A5 JP2023509766A5 (https=) | 2023-12-27 |
| JPWO2021142127A5 JPWO2021142127A5 (https=) | 2023-12-27 |
| JP7690211B2 true JP7690211B2 (ja) | 2025-06-10 |
Family
ID=76788268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022541951A Active JP7690211B2 (ja) | 2020-01-08 | 2021-01-07 | Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230060351A1 (https=) |
| EP (1) | EP4087618A4 (https=) |
| JP (1) | JP7690211B2 (https=) |
| KR (1) | KR20220125805A (https=) |
| CN (1) | CN115243728A (https=) |
| AU (1) | AU2021205249A1 (https=) |
| BR (1) | BR112022013445A2 (https=) |
| CA (1) | CA3166832A1 (https=) |
| MX (1) | MX2022008485A (https=) |
| TW (1) | TW202135840A (https=) |
| WO (1) | WO2021142127A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023070079A1 (en) * | 2021-10-21 | 2023-04-27 | Board Of Regents, The University Of Texas System | Methods for production of therapeutic immune cells having enhanced metabolic fitness and compositions thereof |
| WO2023100153A1 (en) * | 2021-12-03 | 2023-06-08 | Crispr Therapeutics Ag | Use of anti-cd70 antibodies for identifying subjects susceptible for treatment with nk cell-based anti-cd70 therapy |
| JP2025511914A (ja) * | 2022-04-07 | 2025-04-16 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 操作されたナチュラルキラー細胞の活性化および増殖方法と抗体との組み合わせ |
| WO2024251290A1 (en) * | 2023-06-09 | 2024-12-12 | Suzhou Cure Genetics Biosciences Co., Limited | Engineered immune cells and uses thereof |
| CN116769722B (zh) * | 2023-07-04 | 2024-07-16 | 杭州荣谷生物科技有限公司 | 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014509861A (ja) | 2011-03-16 | 2014-04-24 | アルゲン−エックス ビー.ブイ. | Cd70に対する抗体 |
| JP2018505139A (ja) | 2014-12-08 | 2018-02-22 | アメリカ合衆国 | 抗cd70キメラ抗原受容体 |
| WO2018195339A1 (en) | 2017-04-19 | 2018-10-25 | Board Of Regents, The University Of Texas System | Immune cells expressing engineered antigen receptors |
| CN109880802A (zh) | 2018-11-30 | 2019-06-14 | 北京美康基免生物科技有限公司 | 一种基于cd19和cd70的双重嵌合抗原受体基因修饰的免疫细胞及其应用 |
| WO2019152742A1 (en) | 2018-02-01 | 2019-08-08 | Pfizer Inc. | Chimeric antigen receptors targeting cd70 |
| WO2019213610A1 (en) | 2018-05-03 | 2019-11-07 | Board Of Regents, The University Of Texas System | Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201206559D0 (en) * | 2012-04-13 | 2012-05-30 | Ucl Business Plc | Polypeptide |
| ES3063961T3 (en) * | 2014-02-14 | 2026-04-21 | Cellectis | Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells |
| KR102039189B1 (ko) * | 2016-03-23 | 2019-11-01 | 서울대학교산학협력단 | 중증열성혈소판감소증후군 바이러스의 외막 당단백질에 결합하는 항체 및 이의 용도 |
| US20190161542A1 (en) * | 2016-08-01 | 2019-05-30 | Novartis Ag | Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule |
| MX2020012927A (es) * | 2018-06-01 | 2021-03-25 | Univ Southern California | Diversos dominios de enlace de antigenos, nuevas plataformas y otras mejoras para terapia celular. |
-
2021
- 2021-01-07 US US17/758,094 patent/US20230060351A1/en active Pending
- 2021-01-07 KR KR1020227027290A patent/KR20220125805A/ko active Pending
- 2021-01-07 EP EP21738525.1A patent/EP4087618A4/en active Pending
- 2021-01-07 JP JP2022541951A patent/JP7690211B2/ja active Active
- 2021-01-07 CN CN202180019200.XA patent/CN115243728A/zh active Pending
- 2021-01-07 MX MX2022008485A patent/MX2022008485A/es unknown
- 2021-01-07 AU AU2021205249A patent/AU2021205249A1/en active Pending
- 2021-01-07 WO PCT/US2021/012510 patent/WO2021142127A1/en not_active Ceased
- 2021-01-07 CA CA3166832A patent/CA3166832A1/en active Pending
- 2021-01-07 BR BR112022013445A patent/BR112022013445A2/pt unknown
- 2021-01-08 TW TW110100801A patent/TW202135840A/zh unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014509861A (ja) | 2011-03-16 | 2014-04-24 | アルゲン−エックス ビー.ブイ. | Cd70に対する抗体 |
| JP2018505139A (ja) | 2014-12-08 | 2018-02-22 | アメリカ合衆国 | 抗cd70キメラ抗原受容体 |
| WO2018195339A1 (en) | 2017-04-19 | 2018-10-25 | Board Of Regents, The University Of Texas System | Immune cells expressing engineered antigen receptors |
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| WO2021142127A1 (en) | 2021-07-15 |
| AU2021205249A1 (en) | 2022-07-21 |
| MX2022008485A (es) | 2022-08-02 |
| US20230060351A1 (en) | 2023-03-02 |
| BR112022013445A2 (pt) | 2022-09-13 |
| EP4087618A1 (en) | 2022-11-16 |
| CN115243728A (zh) | 2022-10-25 |
| EP4087618A4 (en) | 2024-07-31 |
| JP2023509766A (ja) | 2023-03-09 |
| CA3166832A1 (en) | 2021-07-15 |
| TW202135840A (zh) | 2021-10-01 |
| KR20220125805A (ko) | 2022-09-14 |
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