JP7690211B2 - Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 - Google Patents

Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 Download PDF

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JP7690211B2
JP7690211B2 JP2022541951A JP2022541951A JP7690211B2 JP 7690211 B2 JP7690211 B2 JP 7690211B2 JP 2022541951 A JP2022541951 A JP 2022541951A JP 2022541951 A JP2022541951 A JP 2022541951A JP 7690211 B2 JP7690211 B2 JP 7690211B2
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レズヴァニ、ケイティ
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University of Texas System
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JP2022541951A 2020-01-08 2021-01-07 Cd70陽性腫瘍を標的化するようにナチュラルキラー細胞を操作する方法 Active JP7690211B2 (ja)

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US202062958563P 2020-01-08 2020-01-08
US62/958,563 2020-01-08
PCT/US2021/012510 WO2021142127A1 (en) 2020-01-08 2021-01-07 A method of engineering natural killer cells to target cd70-positive tumors

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JP2023509766A JP2023509766A (ja) 2023-03-09
JP2023509766A5 JP2023509766A5 (https=) 2023-12-27
JPWO2021142127A5 JPWO2021142127A5 (https=) 2023-12-27
JP7690211B2 true JP7690211B2 (ja) 2025-06-10

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US (1) US20230060351A1 (https=)
EP (1) EP4087618A4 (https=)
JP (1) JP7690211B2 (https=)
KR (1) KR20220125805A (https=)
CN (1) CN115243728A (https=)
AU (1) AU2021205249A1 (https=)
BR (1) BR112022013445A2 (https=)
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WO2023070079A1 (en) * 2021-10-21 2023-04-27 Board Of Regents, The University Of Texas System Methods for production of therapeutic immune cells having enhanced metabolic fitness and compositions thereof
WO2023100153A1 (en) * 2021-12-03 2023-06-08 Crispr Therapeutics Ag Use of anti-cd70 antibodies for identifying subjects susceptible for treatment with nk cell-based anti-cd70 therapy
JP2025511914A (ja) * 2022-04-07 2025-04-16 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 操作されたナチュラルキラー細胞の活性化および増殖方法と抗体との組み合わせ
WO2024251290A1 (en) * 2023-06-09 2024-12-12 Suzhou Cure Genetics Biosciences Co., Limited Engineered immune cells and uses thereof
CN116769722B (zh) * 2023-07-04 2024-07-16 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用

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JP2018505139A (ja) 2014-12-08 2018-02-22 アメリカ合衆国 抗cd70キメラ抗原受容体
WO2018195339A1 (en) 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
CN109880802A (zh) 2018-11-30 2019-06-14 北京美康基免生物科技有限公司 一种基于cd19和cd70的双重嵌合抗原受体基因修饰的免疫细胞及其应用
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JP2014509861A (ja) 2011-03-16 2014-04-24 アルゲン−エックス ビー.ブイ. Cd70に対する抗体
JP2018505139A (ja) 2014-12-08 2018-02-22 アメリカ合衆国 抗cd70キメラ抗原受容体
WO2018195339A1 (en) 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
WO2019152742A1 (en) 2018-02-01 2019-08-08 Pfizer Inc. Chimeric antigen receptors targeting cd70
WO2019213610A1 (en) 2018-05-03 2019-11-07 Board Of Regents, The University Of Texas System Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
CN109880802A (zh) 2018-11-30 2019-06-14 北京美康基免生物科技有限公司 一种基于cd19和cd70的双重嵌合抗原受体基因修饰的免疫细胞及其应用

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