CN115243728A - 工程化自然杀伤细胞以靶向cd70阳性肿瘤的方法 - Google Patents

工程化自然杀伤细胞以靶向cd70阳性肿瘤的方法 Download PDF

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CN115243728A
CN115243728A CN202180019200.XA CN202180019200A CN115243728A CN 115243728 A CN115243728 A CN 115243728A CN 202180019200 A CN202180019200 A CN 202180019200A CN 115243728 A CN115243728 A CN 115243728A
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cells
cell
car
expression
expression construct
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K·雷兹瓦尼
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University of Texas System
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CN202180019200.XA 2020-01-08 2021-01-07 工程化自然杀伤细胞以靶向cd70阳性肿瘤的方法 Pending CN115243728A (zh)

Applications Claiming Priority (3)

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US202062958563P 2020-01-08 2020-01-08
US62/958,563 2020-01-08
PCT/US2021/012510 WO2021142127A1 (en) 2020-01-08 2021-01-07 A method of engineering natural killer cells to target cd70-positive tumors

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US (1) US20230060351A1 (https=)
EP (1) EP4087618A4 (https=)
JP (1) JP7690211B2 (https=)
KR (1) KR20220125805A (https=)
CN (1) CN115243728A (https=)
AU (1) AU2021205249A1 (https=)
BR (1) BR112022013445A2 (https=)
CA (1) CA3166832A1 (https=)
MX (1) MX2022008485A (https=)
TW (1) TW202135840A (https=)
WO (1) WO2021142127A1 (https=)

Cited By (1)

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CN116769722A (zh) * 2023-07-04 2023-09-19 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用

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WO2023070079A1 (en) * 2021-10-21 2023-04-27 Board Of Regents, The University Of Texas System Methods for production of therapeutic immune cells having enhanced metabolic fitness and compositions thereof
WO2023100153A1 (en) * 2021-12-03 2023-06-08 Crispr Therapeutics Ag Use of anti-cd70 antibodies for identifying subjects susceptible for treatment with nk cell-based anti-cd70 therapy
JP2025511914A (ja) * 2022-04-07 2025-04-16 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 操作されたナチュラルキラー細胞の活性化および増殖方法と抗体との組み合わせ
WO2024251290A1 (en) * 2023-06-09 2024-12-12 Suzhou Cure Genetics Biosciences Co., Limited Engineered immune cells and uses thereof

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ES3063961T3 (en) * 2014-02-14 2026-04-21 Cellectis Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells
CN113968913A (zh) * 2014-12-08 2022-01-25 美国卫生和人力服务部 抗cd70嵌合抗原受体
KR102039189B1 (ko) * 2016-03-23 2019-11-01 서울대학교산학협력단 중증열성혈소판감소증후군 바이러스의 외막 당단백질에 결합하는 항체 및 이의 용도
US20190161542A1 (en) * 2016-08-01 2019-05-30 Novartis Ag Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
WO2018195339A1 (en) * 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
KR102780406B1 (ko) * 2018-02-01 2025-03-17 화이자 인코포레이티드 Cd70을 표적으로 하는 키메라 항원 수용체
MX2020011697A (es) * 2018-05-03 2020-12-10 Univ Texas Células exterminadoras naturales diseñadas para expresar receptores de antígeno quimérico con bloqueo de punto de control inmunitario.
MX2020012927A (es) * 2018-06-01 2021-03-25 Univ Southern California Diversos dominios de enlace de antigenos, nuevas plataformas y otras mejoras para terapia celular.
CN109880802B (zh) * 2018-11-30 2022-12-13 北京美康基免生物科技有限公司 一种基于cd19和cd70的双重嵌合抗原受体基因修饰的免疫细胞及其应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116769722A (zh) * 2023-07-04 2023-09-19 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用

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JP7690211B2 (ja) 2025-06-10
AU2021205249A1 (en) 2022-07-21
MX2022008485A (es) 2022-08-02
US20230060351A1 (en) 2023-03-02
BR112022013445A2 (pt) 2022-09-13
EP4087618A1 (en) 2022-11-16
EP4087618A4 (en) 2024-07-31
JP2023509766A (ja) 2023-03-09
CA3166832A1 (en) 2021-07-15
TW202135840A (zh) 2021-10-01
KR20220125805A (ko) 2022-09-14

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