JP7657725B2 - 脂溶性ビタミンのための新規送達システム - Google Patents

脂溶性ビタミンのための新規送達システム Download PDF

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Publication number
JP7657725B2
JP7657725B2 JP2021556521A JP2021556521A JP7657725B2 JP 7657725 B2 JP7657725 B2 JP 7657725B2 JP 2021556521 A JP2021556521 A JP 2021556521A JP 2021556521 A JP2021556521 A JP 2021556521A JP 7657725 B2 JP7657725 B2 JP 7657725B2
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Japan
Prior art keywords
delivery system
delivery formulation
fat
inner coating
coating
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JP2021556521A
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English (en)
Japanese (ja)
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JPWO2020221572A5 (https=
JP2022530307A5 (https=
JP2022530307A (ja
Inventor
エルガー フンダ，
オディール クラインツ，
ロベルト シュタイネール，
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DSM IP Assets BV
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DSM IP Assets BV
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Publication of JP2022530307A5 publication Critical patent/JP2022530307A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2021556521A 2019-04-30 2020-04-09 脂溶性ビタミンのための新規送達システム Active JP7657725B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19171752 2019-04-30
EP19171752.9 2019-04-30
PCT/EP2020/060161 WO2020221572A1 (en) 2019-04-30 2020-04-09 New delivery system for fat soluble vitamins

Publications (4)

Publication Number Publication Date
JP2022530307A JP2022530307A (ja) 2022-06-29
JPWO2020221572A5 JPWO2020221572A5 (https=) 2024-05-10
JP2022530307A5 JP2022530307A5 (https=) 2024-05-10
JP7657725B2 true JP7657725B2 (ja) 2025-04-07

Family

ID=66429183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021556521A Active JP7657725B2 (ja) 2019-04-30 2020-04-09 脂溶性ビタミンのための新規送達システム

Country Status (7)

Country Link
US (1) US12419841B2 (https=)
EP (1) EP3962461A1 (https=)
JP (1) JP7657725B2 (https=)
KR (1) KR20220003039A (https=)
CN (1) CN113727706A (https=)
BR (1) BR112021021390A2 (https=)
WO (1) WO2020221572A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070098790A1 (en) 2005-10-31 2007-05-03 David Jiang Nutritional supplement for the enhancement of the health of the liver
JP2010121028A (ja) 2008-11-19 2010-06-03 Ina Food Industry Co Ltd 改質キサンタンガム、改質アラビアガム、及び改質タマリンドシードガム、並びにキサンタンガム、アラビアガム、及びタマリンドシードガムの架橋方法
JP2014534959A (ja) 2011-10-14 2014-12-25 ディーエスエム アイピー アセッツ ビー．ブイ． 新規コーティングシステム
JP2016124801A (ja) 2014-12-26 2016-07-11 ポーラ化成工業株式会社 カプセル体及びその製造方法
JP2017532050A (ja) 2014-12-09 2017-11-02 インターコンチネンタル グレート ブランズ エルエルシー 腸溶性被覆機能性食品成分及び腸溶性被覆機能性食品成分の製造方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389419A (en) * 1980-11-10 1983-06-21 Damon Corporation Vitamin encapsulation
US4670247A (en) * 1983-07-05 1987-06-02 Hoffman-Laroche Inc. Process for preparing fat-soluble vitamin active beadlets
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
JP2939403B2 (ja) * 1993-02-05 1999-08-25 義秀 萩原 プロラクチン又は成長ホルモンの分泌促進剤
US6620431B1 (en) * 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
US7097868B2 (en) * 2001-08-23 2006-08-29 Bio-Dar Ltd. Stable coated microcapsules
JP4593846B2 (ja) * 2001-09-07 2010-12-08 信越化学工業株式会社 医薬品又は食品用マイクロカプセルの製造方法
JP2004168703A (ja) 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
EP1940249B1 (en) * 2005-10-21 2015-06-03 DSM IP Assets B.V. Novel formulations of fat-soluble active ingredients with high bioavailability
US20170296476A1 (en) * 2016-04-15 2017-10-19 Grünenthal GmbH Modified release abuse deterrent dosage forms
US11771656B2 (en) 2016-11-17 2023-10-03 Shanghai Jiaotong University School Of Medicine Oral colon-targeted delivery system and preparation method and application thereof
JP2020536930A (ja) * 2017-10-13 2020-12-17 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 放出調節乱用防止剤形
CN109511785A (zh) * 2018-12-25 2019-03-26 乐山市瑞和祥动物保健药业有限公司 一种兽用复合维生素微丸及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070098790A1 (en) 2005-10-31 2007-05-03 David Jiang Nutritional supplement for the enhancement of the health of the liver
JP2010121028A (ja) 2008-11-19 2010-06-03 Ina Food Industry Co Ltd 改質キサンタンガム、改質アラビアガム、及び改質タマリンドシードガム、並びにキサンタンガム、アラビアガム、及びタマリンドシードガムの架橋方法
JP2014534959A (ja) 2011-10-14 2014-12-25 ディーエスエム アイピー アセッツ ビー．ブイ． 新規コーティングシステム
JP2017532050A (ja) 2014-12-09 2017-11-02 インターコンチネンタル グレート ブランズ エルエルシー 腸溶性被覆機能性食品成分及び腸溶性被覆機能性食品成分の製造方法
JP2016124801A (ja) 2014-12-26 2016-07-11 ポーラ化成工業株式会社 カプセル体及びその製造方法

Also Published As

Publication number Publication date
US20220226254A1 (en) 2022-07-21
KR20220003039A (ko) 2022-01-07
CN113727706A (zh) 2021-11-30
EP3962461A1 (en) 2022-03-09
US12419841B2 (en) 2025-09-23
BR112021021390A2 (pt) 2021-12-21
WO2020221572A1 (en) 2020-11-05
JP2022530307A (ja) 2022-06-29

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