JP7642635B2 - メタロ－ベータ－ラクタマーゼ阻害剤としての１－アミノスルホニル－２－カルボキシピロール誘導体 - Google Patents

メタロ－ベータ－ラクタマーゼ阻害剤としての１－アミノスルホニル－２－カルボキシピロール誘導体 Download PDF

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JP7642635B2
JP7642635B2 JP2022529304A JP2022529304A JP7642635B2 JP 7642635 B2 JP7642635 B2 JP 7642635B2 JP 2022529304 A JP2022529304 A JP 2022529304A JP 2022529304 A JP2022529304 A JP 2022529304A JP 7642635 B2 JP7642635 B2 JP 7642635B2
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JP2023502415A5 (https=
JP2023502415A (ja
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ウィルキンソン，アンドリュー
クーパー，イアン
オー，デイビッド
フィンレイソン，ジョナサン
バント，アダム
アペルクヴィスト，ピア
ヴァルバリ，ハンス
ヴォーンセル，フレードリク
カーカム，ジェイムズ
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Infex Therapeutics Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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JP2022529304A 2019-11-20 2020-11-19 メタロ－ベータ－ラクタマーゼ阻害剤としての１－アミノスルホニル－２－カルボキシピロール誘導体 Active JP7642635B2 (ja)

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CN117050063B (zh) * 2023-08-14 2024-02-09 宁夏佰斯特医药化工有限公司 一种三氟乙酸酯三氮唑衍生物的合成方法

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