JP7634480B2 - フェノール誘導体の製造方法 - Google Patents

フェノール誘導体の製造方法 Download PDF

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Publication number
JP7634480B2
JP7634480B2 JP2021533996A JP2021533996A JP7634480B2 JP 7634480 B2 JP7634480 B2 JP 7634480B2 JP 2021533996 A JP2021533996 A JP 2021533996A JP 2021533996 A JP2021533996 A JP 2021533996A JP 7634480 B2 JP7634480 B2 JP 7634480B2
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methyl
alkyl
substituent
general formula
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Japanese (ja)
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JPWO2021015109A5 (https=
JPWO2021015109A1 (https=
Inventor
雅朗 廣瀬
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Nippon Chemiphar Co Ltd
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Nippon Chemiphar Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021533996A 2019-07-19 2020-07-17 フェノール誘導体の製造方法 Active JP7634480B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025017540A JP2025072517A (ja) 2019-07-19 2025-02-05 フェノール誘導体の製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019134083 2019-07-19
JP2019134083 2019-07-19
PCT/JP2020/027769 WO2021015109A1 (ja) 2019-07-19 2020-07-17 フェノール誘導体の製造方法

Related Child Applications (1)

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JP2025017540A Division JP2025072517A (ja) 2019-07-19 2025-02-05 フェノール誘導体の製造方法

Publications (3)

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JPWO2021015109A1 JPWO2021015109A1 (https=) 2021-01-28
JPWO2021015109A5 JPWO2021015109A5 (https=) 2023-07-21
JP7634480B2 true JP7634480B2 (ja) 2025-02-21

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JP2021533996A Active JP7634480B2 (ja) 2019-07-19 2020-07-17 フェノール誘導体の製造方法
JP2025017540A Pending JP2025072517A (ja) 2019-07-19 2025-02-05 フェノール誘導体の製造方法

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JP2025017540A Pending JP2025072517A (ja) 2019-07-19 2025-02-05 フェノール誘導体の製造方法

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US (1) US20220289748A1 (https=)
EP (1) EP4001280A4 (https=)
JP (2) JP7634480B2 (https=)
KR (1) KR20220035378A (https=)
CN (1) CN114127069A (https=)
AU (1) AU2020317503A1 (https=)
CA (1) CA3147221A1 (https=)
WO (1) WO2021015109A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025072517A (ja) * 2019-07-19 2025-05-09 日本ケミファ株式会社 フェノール誘導体の製造方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7816720B2 (ja) 2021-11-25 2026-02-18 エルジー エナジー ソリューション リミテッド 負極活物質、負極、および二次電池

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013035833A1 (ja) 2011-09-09 2013-03-14 学校法人北里研究所 モルヒナン誘導体
WO2014021273A1 (ja) 2012-07-30 2014-02-06 学校法人北里研究所 モルヒナン誘導体
WO2014136305A1 (ja) 2013-03-08 2014-09-12 学校法人北里研究所 モルヒナン誘導体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ281174B6 (cs) 1993-08-13 1996-07-17 Galena, A.S. Způsob přípravy 3,14ß-dihydroxy-17-normorfinanu
AR091027A1 (es) 2012-05-11 2014-12-30 Purdue Pharma Lp Analogos de benzomorfano y el usos de estos
JP2015180605A (ja) 2012-07-30 2015-10-15 学校法人北里研究所 モルヒナン誘導体
US8946255B2 (en) 2012-12-28 2015-02-03 Purdue Pharma L.P. Substituted morphinans and the use thereof
WO2014102587A1 (en) 2012-12-28 2014-07-03 Purdue Pharma L.P. 7,8-cyclicmorphinan analogs
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CN113292559B (zh) * 2015-03-17 2024-04-02 日本化学药品株式会社 吗啡喃衍生物
US10766864B2 (en) 2015-05-08 2020-09-08 Nektar Therapeutics Morphinan derivatives for the treatment of neuropathic pain
AU2020317503A1 (en) * 2019-07-19 2022-02-10 Nippon Chemiphar Co., Ltd. Method for producing phenol derivative
US12202830B2 (en) * 2019-07-19 2025-01-21 Nippon Chemiphar Co., Ltd. Method for producing morphinan derivative

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013035833A1 (ja) 2011-09-09 2013-03-14 学校法人北里研究所 モルヒナン誘導体
WO2014021273A1 (ja) 2012-07-30 2014-02-06 学校法人北里研究所 モルヒナン誘導体
WO2014136305A1 (ja) 2013-03-08 2014-09-12 学校法人北里研究所 モルヒナン誘導体

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HAYASHIDA Kohei, et al.，Novel delta opioid receptor agonists with oxazatricyclodecane structure showing potent agonistic act，Bioorganic & Medicinal Chemistry Letters，2017年，Vol.27(12)，p.2742-2745
WATANABE Yoshikazu, et al.，Design and synthesis of novel δ opioid receptor agonists with an azatricyclodecane skeleton for imp，Bioorganic & Medicinal Chemistry Letters，2017年，Vol.27(15)，p.3495-3498

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025072517A (ja) * 2019-07-19 2025-05-09 日本ケミファ株式会社 フェノール誘導体の製造方法

Also Published As

Publication number Publication date
US20220289748A1 (en) 2022-09-15
CN114127069A (zh) 2022-03-01
JP2025072517A (ja) 2025-05-09
CA3147221A1 (en) 2021-01-28
AU2020317503A1 (en) 2022-02-10
EP4001280A4 (en) 2023-07-12
EP4001280A1 (en) 2022-05-25
WO2021015109A1 (ja) 2021-01-28
KR20220035378A (ko) 2022-03-22
JPWO2021015109A1 (https=) 2021-01-28

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