KR20220035378A - 페놀 유도체의 제조 방법 - Google Patents

페놀 유도체의 제조 방법 Download PDF

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Publication number
KR20220035378A
KR20220035378A KR1020227001216A KR20227001216A KR20220035378A KR 20220035378 A KR20220035378 A KR 20220035378A KR 1020227001216 A KR1020227001216 A KR 1020227001216A KR 20227001216 A KR20227001216 A KR 20227001216A KR 20220035378 A KR20220035378 A KR 20220035378A
Authority
KR
South Korea
Prior art keywords
group
substituent
production method
hydrogen atom
morphinan derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020227001216A
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English (en)
Korean (ko)
Inventor
마사아키 히로세
Original Assignee
닛뽕 케미파 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 닛뽕 케미파 가부시키가이샤 filed Critical 닛뽕 케미파 가부시키가이샤
Publication of KR20220035378A publication Critical patent/KR20220035378A/ko
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020227001216A 2019-07-19 2020-07-17 페놀 유도체의 제조 방법 Pending KR20220035378A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019134083 2019-07-19
JPJP-P-2019-134083 2019-07-19
PCT/JP2020/027769 WO2021015109A1 (ja) 2019-07-19 2020-07-17 フェノール誘導体の製造方法

Publications (1)

Publication Number Publication Date
KR20220035378A true KR20220035378A (ko) 2022-03-22

Family

ID=74193222

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227001216A Pending KR20220035378A (ko) 2019-07-19 2020-07-17 페놀 유도체의 제조 방법

Country Status (8)

Country Link
US (1) US20220289748A1 (https=)
EP (1) EP4001280A4 (https=)
JP (2) JP7634480B2 (https=)
KR (1) KR20220035378A (https=)
CN (1) CN114127069A (https=)
AU (1) AU2020317503A1 (https=)
CA (1) CA3147221A1 (https=)
WO (1) WO2021015109A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023096346A1 (ko) 2021-11-25 2023-06-01 주식회사 엘지에너지솔루션 음극 활물질, 음극 및 이차 전지

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020317503A1 (en) * 2019-07-19 2022-02-10 Nippon Chemiphar Co., Ltd. Method for producing phenol derivative

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504208A (en) 1993-08-13 1996-04-02 Galena A.S. Process for the preparation of 3, 14β-dihydroxy-17-normorphinan
WO2013035833A1 (ja) 2011-09-09 2013-03-14 学校法人北里研究所 モルヒナン誘導体
WO2013167963A1 (en) 2012-05-11 2013-11-14 Purdue Pharma L.P. Benzomorphan compounds as opioid receptors modulators
WO2014021273A1 (ja) 2012-07-30 2014-02-06 学校法人北里研究所 モルヒナン誘導体
WO2014102593A1 (en) 2012-12-28 2014-07-03 Purdue Pharma L.P. Substituted morphinans and the use thereof
WO2014102587A1 (en) 2012-12-28 2014-07-03 Purdue Pharma L.P. 7,8-cyclicmorphinan analogs
WO2014136305A1 (ja) 2013-03-08 2014-09-12 学校法人北里研究所 モルヒナン誘導体
US20150072971A1 (en) 2013-05-24 2015-03-12 Alkermes Pharma Ireland Limited Methods for Treating Depressive Symptoms
JP2015180605A (ja) 2012-07-30 2015-10-15 学校法人北里研究所 モルヒナン誘導体
WO2016148232A1 (ja) 2015-03-17 2016-09-22 国立大学法人 筑波大学 モルヒナン誘導体
WO2016182840A1 (en) 2015-05-08 2016-11-17 Nektar Therapeutics Morphinan derivatives for the treatment of neuropathic pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020317503A1 (en) * 2019-07-19 2022-02-10 Nippon Chemiphar Co., Ltd. Method for producing phenol derivative
US12202830B2 (en) * 2019-07-19 2025-01-21 Nippon Chemiphar Co., Ltd. Method for producing morphinan derivative

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504208A (en) 1993-08-13 1996-04-02 Galena A.S. Process for the preparation of 3, 14β-dihydroxy-17-normorphinan
WO2013035833A1 (ja) 2011-09-09 2013-03-14 学校法人北里研究所 モルヒナン誘導体
WO2013167963A1 (en) 2012-05-11 2013-11-14 Purdue Pharma L.P. Benzomorphan compounds as opioid receptors modulators
WO2014021273A1 (ja) 2012-07-30 2014-02-06 学校法人北里研究所 モルヒナン誘導体
JP2015180605A (ja) 2012-07-30 2015-10-15 学校法人北里研究所 モルヒナン誘導体
WO2014102593A1 (en) 2012-12-28 2014-07-03 Purdue Pharma L.P. Substituted morphinans and the use thereof
WO2014102587A1 (en) 2012-12-28 2014-07-03 Purdue Pharma L.P. 7,8-cyclicmorphinan analogs
WO2014136305A1 (ja) 2013-03-08 2014-09-12 学校法人北里研究所 モルヒナン誘導体
US20150072971A1 (en) 2013-05-24 2015-03-12 Alkermes Pharma Ireland Limited Methods for Treating Depressive Symptoms
WO2016148232A1 (ja) 2015-03-17 2016-09-22 国立大学法人 筑波大学 モルヒナン誘導体
WO2016182840A1 (en) 2015-05-08 2016-11-17 Nektar Therapeutics Morphinan derivatives for the treatment of neuropathic pain

Non-Patent Citations (16)

* Cited by examiner, † Cited by third party
Title
Bioorganic ＆ Medicinal Chemistry Letters, 19 (16), 4603-4606, 2009
Bioorganic ＆ Medicinal Chemistry Letters, 22, 5071-5074, 2012
Bioorganic ＆ Medicinal Chemistry Letters, 22, 7711-7714, 2012
Bioorganic ＆ Medicinal Chemistry Letters, 27 (12), 2742-2745, 2017
Bioorganic ＆ Medicinal Chemistry Letters, 27 (15), 3495-3498, 2017
Chemical Biology ＆ Drug Design, 74 (4), 335-342, 2009
Helvetica Chimica Acta, 72 (6), 1233-1240, 1989
Helvetica Chimica Acta, 73 (2), 326-36, 1990
Journal of Medicinal Chemistry, 33 (4), 1200-1206, 1990
Journal of Medicinal Chemistry, 50 (11), 2747-2751, 2007
Journal of Medicinal Chemistry, 58 (12), 5038-5052, 2015
Journal of Organic Chemistry, 30 (6), 1769-1773, 1965
Journal of Organic Chemistry, 73, 8093-8096, 2008
Recueil des Travaux Chimiques des Pays-Bas, 107 (6), 449-54, 1988
Tetrahedron Letters, 51 (17), 2359-2361, 2010
Tetrahedron, 24 (20), 6185-96, 1968

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023096346A1 (ko) 2021-11-25 2023-06-01 주식회사 엘지에너지솔루션 음극 활물질, 음극 및 이차 전지

Also Published As

Publication number Publication date
US20220289748A1 (en) 2022-09-15
CN114127069A (zh) 2022-03-01
JP2025072517A (ja) 2025-05-09
CA3147221A1 (en) 2021-01-28
AU2020317503A1 (en) 2022-02-10
EP4001280A4 (en) 2023-07-12
EP4001280A1 (en) 2022-05-25
WO2021015109A1 (ja) 2021-01-28
JP7634480B2 (ja) 2025-02-21
JPWO2021015109A1 (https=) 2021-01-28

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