JP7609468B2 - ＳＡＲＳ－ＣｏＶ－２スパイク糖タンパク質結合核酸分子、ＳＡＲＳ－ＣｏＶ－２検出用センサ、ＳＡＲＳ－ＣｏＶ－２検出試薬、ＳＡＲＳ－ＣｏＶ－２の検出方法、およびＳＡＲＳ－ＣｏＶ－２ウイルスの不活性化剤 - Google Patents

ＳＡＲＳ－ＣｏＶ－２スパイク糖タンパク質結合核酸分子、ＳＡＲＳ－ＣｏＶ－２検出用センサ、ＳＡＲＳ－ＣｏＶ－２検出試薬、ＳＡＲＳ－ＣｏＶ－２の検出方法、およびＳＡＲＳ－ＣｏＶ－２ウイルスの不活性化剤 Download PDF

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JP7609468B2
JP7609468B2 JP2022565082A JP2022565082A JP7609468B2 JP 7609468 B2 JP7609468 B2 JP 7609468B2 JP 2022565082 A JP2022565082 A JP 2022565082A JP 2022565082 A JP2022565082 A JP 2022565082A JP 7609468 B2 JP7609468 B2 JP 7609468B2
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sars
nucleic acid
acid molecule
seq
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JPWO2022113496A5 (https=
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宏貴 皆川
智子 藤田
信太郎 加藤
あすみ 稲熊
克紀 堀井
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NEC Solution Innovators Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/33—Chemical structure of the base
    • C12N2310/335—Modified T or U
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2022565082A 2020-11-30 2021-09-22 ＳＡＲＳ－ＣｏＶ－２スパイク糖タンパク質結合核酸分子、ＳＡＲＳ－ＣｏＶ－２検出用センサ、ＳＡＲＳ－ＣｏＶ－２検出試薬、ＳＡＲＳ－ＣｏＶ－２の検出方法、およびＳＡＲＳ－ＣｏＶ－２ウイルスの不活性化剤 Active JP7609468B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020198556 2020-11-30
JP2020198556 2020-11-30
PCT/JP2021/034667 WO2022113496A1 (ja) 2020-11-30 2021-09-22 ＳＡＲＳ－ＣｏＶ－２スパイク糖タンパク質結合核酸分子、ＳＡＲＳ－ＣｏＶ－２検出用センサ、ＳＡＲＳ－ＣｏＶ－２検出試薬、ＳＡＲＳ－ＣｏＶ－２の検出方法、およびＳＡＲＳ－ＣｏＶ－２ウイルスの不活性化剤

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JPWO2022113496A1 JPWO2022113496A1 (https=) 2022-06-02
JPWO2022113496A5 JPWO2022113496A5 (https=) 2023-06-23
JP7609468B2 true JP7609468B2 (ja) 2025-01-07

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US (1) US20240002860A1 (https=)
EP (1) EP4253545A4 (https=)
JP (1) JP7609468B2 (https=)
CN (1) CN116710553A (https=)
WO (1) WO2022113496A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111849994A (zh) 2020-03-31 2020-10-30 厦门大学 SARS-CoV-2 S蛋白或RBD蛋白的核酸适配体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018051580A1 (ja) 2016-09-15 2018-03-22 Ｎｅｃソリューションイノベータ株式会社 ヌクレオシド誘導体またはその塩、ポリヌクレオチドの合成試薬、ポリヌクレオチドの製造方法、ポリヌクレオチド、および結合核酸分子の製造方法
JP7348754B2 (ja) 2019-06-03 2023-09-21 キヤノン株式会社 画像処理装置及びその制御方法、プログラム、記憶媒体

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111849994A (zh) 2020-03-31 2020-10-30 厦门大学 SARS-CoV-2 S蛋白或RBD蛋白的核酸适配体及其应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
LIU, Ran et al.，A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutraliz，Chemical Science，2020年10月12日，Volume 11, Issue 44, 12157-12164， and Supporting Information pp. 1-26
SONG, Yanling et al.，Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein，Analytical Chemistry，2020年06月18日，A-F
WEISSHOFF, Hardy et al.，Aptamer BC 007 - Efficient binder of spreading-crucial SARS-CoV-2 proteins，Heliyon，2020年11月02日，Volume 6, Issue 11，1-8

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Publication number Publication date
WO2022113496A1 (ja) 2022-06-02
US20240002860A1 (en) 2024-01-04
CN116710553A (zh) 2023-09-05
EP4253545A1 (en) 2023-10-04
JPWO2022113496A1 (https=) 2022-06-02
EP4253545A4 (en) 2024-06-19

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