JP7587921B2 - 抗クローディンタンパク質１８ａ２の抗体及びその応用 - Google Patents

抗クローディンタンパク質１８ａ２の抗体及びその応用 Download PDF

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JP7587921B2
JP7587921B2 JP2019521178A JP2019521178A JP7587921B2 JP 7587921 B2 JP7587921 B2 JP 7587921B2 JP 2019521178 A JP2019521178 A JP 2019521178A JP 2019521178 A JP2019521178 A JP 2019521178A JP 7587921 B2 JP7587921 B2 JP 7587921B2
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seq
antibody
cell
cells
variable region
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JP2019531084A5 (enExample
JP2019531084A (ja
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ポン ワン，
ホア チアン，
リンリン ヤン，
チーミン シー，
ホアマオ ワン，
ツォンハイ リー，
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Crage Medical Co Ltd
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Crage Medical Co Ltd
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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JP2019521178A 2016-07-08 2017-07-10 抗クローディンタンパク質１８ａ２の抗体及びその応用 Active JP7587921B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN201610536449 2016-07-08
CN201610536449.9 2016-07-08
CNPCT/CN2017/082024 2017-04-26
PCT/CN2017/082024 WO2017186121A1 (zh) 2016-04-26 2017-04-26 一种改善免疫应答细胞功能的方法
PCT/CN2017/092381 WO2018006882A1 (zh) 2016-07-08 2017-07-10 抗密蛋白18a2的抗体及其应用

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JP2019531084A JP2019531084A (ja) 2019-10-31
JP2019531084A5 JP2019531084A5 (enExample) 2020-09-03
JP7587921B2 true JP7587921B2 (ja) 2024-11-21

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US (2) US11111295B2 (enExample)
EP (1) EP3483182B1 (enExample)
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KR (1) KR102723896B1 (enExample)
CN (1) CN109790222B (enExample)
AU (1) AU2017294276B2 (enExample)
BR (1) BR112019000327A8 (enExample)
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CN109790222B (zh) * 2016-07-08 2022-03-15 克莱格医学有限公司 抗密蛋白18a2的抗体及其应用
US12178786B2 (en) 2018-02-02 2024-12-31 Crage Medical Co., Limited Combination of cellular immunotherapy
EP3762031A4 (en) 2018-03-08 2021-12-22 Phanes Therapeutics, Inc. ANTI-CLAUDINE ANTIBODIES 18.2 AND THEIR USES
KR20210013013A (ko) * 2018-03-09 2021-02-03 카르스젠 테라퓨틱스 리미티드 종양 치료 방법 및 조성물
CN112166123B (zh) * 2018-03-14 2022-09-30 北京轩义医药科技有限公司 抗紧密连接蛋白18.2抗体
EP3789486A4 (en) * 2018-05-03 2022-03-30 Cafa Therapeutics Limited Immune effector cell and use thereof
EP3822345B1 (en) 2018-05-15 2024-10-16 CRAGE medical Co., Limited Genetically engineered cell and application thereof
CN116178554B (zh) * 2018-05-18 2025-09-09 礼新医药科技(上海)有限公司 抗密蛋白18.2抗体及其用途
CA3107515A1 (en) 2018-07-24 2020-01-30 Carsgen Therapeutics Co., Ltd. Method for tumor treatment with immune effector cells
CN112770723B (zh) * 2018-07-25 2024-08-02 阿克罗斯生物科学公司 Cldn 18.2特异性单克隆抗体及其使用方法
CN110857322A (zh) * 2018-08-22 2020-03-03 瑞阳(苏州)生物科技有限公司 抗人claudin 18.2单克隆抗体及其应用
CN112654638B (zh) * 2018-08-27 2022-12-30 南京圣和药业股份有限公司 一种抗Claudin18.2抗体及其应用
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