JP7558204B2 - 遅延放出ソフトゲルカプセル - Google Patents
遅延放出ソフトゲルカプセル Download PDFInfo
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- JP7558204B2 JP7558204B2 JP2021571794A JP2021571794A JP7558204B2 JP 7558204 B2 JP7558204 B2 JP 7558204B2 JP 2021571794 A JP2021571794 A JP 2021571794A JP 2021571794 A JP2021571794 A JP 2021571794A JP 7558204 B2 JP7558204 B2 JP 7558204B2
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- JP
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- Prior art keywords
- dependent
- delayed release
- minutes
- shell composition
- pectin
- Prior art date
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- 235000019148 tocotrienols Nutrition 0.000 description 1
- 229960002905 tolfenamic acid Drugs 0.000 description 1
- YEZNLOUZAIOMLT-UHFFFAOYSA-N tolfenamic acid Chemical compound CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O YEZNLOUZAIOMLT-UHFFFAOYSA-N 0.000 description 1
- 229960001017 tolmetin Drugs 0.000 description 1
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- 229960003386 triazolam Drugs 0.000 description 1
- JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 description 1
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- 235000001019 trigonella foenum-graecum Nutrition 0.000 description 1
- FQCQGOZEWWPOKI-UHFFFAOYSA-K trisalicylate-choline Chemical compound [Mg+2].C[N+](C)(C)CCO.OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O FQCQGOZEWWPOKI-UHFFFAOYSA-K 0.000 description 1
- 235000013976 turmeric Nutrition 0.000 description 1
- 229960002004 valdecoxib Drugs 0.000 description 1
- LNPDTQAFDNKSHK-UHFFFAOYSA-N valdecoxib Chemical compound CC=1ON=C(C=2C=CC=CC=2)C=1C1=CC=C(S(N)(=O)=O)C=C1 LNPDTQAFDNKSHK-UHFFFAOYSA-N 0.000 description 1
- 235000016788 valerian Nutrition 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- GPPXJZIENCGNKB-UHFFFAOYSA-N vanadium Chemical compound [V]#[V] GPPXJZIENCGNKB-UHFFFAOYSA-N 0.000 description 1
- UUUGYDOQQLOJQA-UHFFFAOYSA-L vanadyl sulfate Chemical compound [V+2]=O.[O-]S([O-])(=O)=O UUUGYDOQQLOJQA-UHFFFAOYSA-L 0.000 description 1
- 229940041260 vanadyl sulfate Drugs 0.000 description 1
- 229910000352 vanadyl sulfate Inorganic materials 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000009492 vitamin B5 Nutrition 0.000 description 1
- 239000011675 vitamin B5 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000008170 walnut oil Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000001841 zingiber officinale Substances 0.000 description 1
- 229960003414 zomepirac Drugs 0.000 description 1
- ZXVNMYWKKDOREA-UHFFFAOYSA-N zomepirac Chemical compound C1=C(CC(O)=O)N(C)C(C(=O)C=2C=CC(Cl)=CC=2)=C1C ZXVNMYWKKDOREA-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962856601P | 2019-06-03 | 2019-06-03 | |
| US62/856,601 | 2019-06-03 | ||
| PCT/US2020/035666 WO2020247352A1 (en) | 2019-06-03 | 2020-06-02 | Delayed release softgel capsules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022535539A JP2022535539A (ja) | 2022-08-09 |
| JPWO2020247352A5 JPWO2020247352A5 (enExample) | 2023-06-09 |
| JP7558204B2 true JP7558204B2 (ja) | 2024-09-30 |
Family
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| JP2021571794A Active JP7558204B2 (ja) | 2019-06-03 | 2020-06-02 | 遅延放出ソフトゲルカプセル |
Country Status (14)
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|---|---|
| US (1) | US20220354800A1 (enExample) |
| EP (1) | EP3976022A4 (enExample) |
| JP (1) | JP7558204B2 (enExample) |
| KR (1) | KR20220024189A (enExample) |
| CN (1) | CN114072138A (enExample) |
| AR (1) | AR119075A1 (enExample) |
| AU (1) | AU2020288165A1 (enExample) |
| BR (1) | BR112021024375A2 (enExample) |
| CA (1) | CA3142702A1 (enExample) |
| CO (1) | CO2021018071A2 (enExample) |
| IL (1) | IL288653A (enExample) |
| MX (1) | MX2021014922A (enExample) |
| TW (1) | TW202110426A (enExample) |
| WO (1) | WO2020247352A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021024375A2 (pt) * | 2019-06-03 | 2022-04-19 | Scherer Technologies Llc R P | Cápsulas de softgel de liberação retardada |
| KR20230018445A (ko) * | 2020-06-02 | 2023-02-07 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 지연 방출 소프트겔 캡슐 |
| KR20230106642A (ko) * | 2020-11-11 | 2023-07-13 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 지연 방출 소프트겔 캡슐 |
| JP2024512659A (ja) * | 2021-04-01 | 2024-03-19 | アール．ピー．シェーラー テクノロジーズ，エルエルシー | 医薬製剤におけるアニオン性キレート剤としてのリン脂質 |
| MX2024000409A (es) * | 2021-07-06 | 2024-01-29 | Scherer Technologies Llc R P | Capsula de gelatina blanda. |
| JP2025506678A (ja) * | 2022-02-18 | 2025-03-13 | アール．ピー．シェーラー テクノロジーズ，エルエルシー | 調節放出バルプロ酸ソフトゲルカプセル |
| DE102022104553A1 (de) * | 2022-02-25 | 2023-08-31 | Gelita Ag | Magensaftresistente Kapsel und deren Verwendung |
| WO2023244533A1 (en) * | 2022-06-13 | 2023-12-21 | R.P. Scherer Technologies, Llc | Enteric bisacodyl softgel capsule |
| WO2024112786A1 (en) * | 2022-11-23 | 2024-05-30 | R.P. Scherer Technologies, Llc | Softgel capsule and method of marking a softgel capsule |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120301546A1 (en) | 2011-05-26 | 2012-11-29 | Hassan Emadeldin M | Acid-resistant soft gel compositions |
| CN104644609A (zh) | 2015-01-28 | 2015-05-27 | 龙标兵 | 一种功能性咀嚼型软胶囊皮 |
| JP2018531985A (ja) | 2015-10-30 | 2018-11-01 | アール．ピー． シェーラー テクノロジーズ エルエルシー | 延長放出性フィルムコーティングカプセル |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4778676A (en) * | 1985-12-20 | 1988-10-18 | Warner-Lambert Company | Confectionery delivery system for actives |
| EP1184033A1 (en) * | 2000-09-01 | 2002-03-06 | Warner-Lambert Company | Pectin film compositions |
| AU2002366038B2 (en) * | 2001-11-22 | 2007-08-02 | Morishita Jintan Co., Ltd. | Non-gelatinous capsule film compositions and capsules using the same |
| US20040224020A1 (en) * | 2002-12-18 | 2004-11-11 | Schoenhard Grant L. | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
| CN101292965B (zh) | 2007-04-24 | 2011-12-07 | 沈阳皓天万嘉医药科技有限公司 | 一种类β-胡萝卜素微囊及其制备方法 |
| US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| CN101461792A (zh) * | 2008-12-30 | 2009-06-24 | 吴国庆 | 明胶肠溶胶囊壳材料 |
| CA2805127A1 (en) * | 2009-08-05 | 2011-02-10 | 7267207 Canada Limited Corporation | Process for preparation of over-the-counter gelatin or pectin-based drug delivery |
| IT1401313B1 (it) * | 2010-08-05 | 2013-07-18 | Perfetti Van Melle Spa | Caramelle gelatinose con ripieno fluido e metodo di ottenimento |
| CN102813275B (zh) * | 2011-06-10 | 2015-09-30 | 杭州养生堂保健品有限公司 | 一种咀嚼型软胶囊皮和咀嚼型软胶囊 |
| JP5876695B2 (ja) * | 2011-09-29 | 2016-03-02 | 森下仁丹株式会社 | シームレスカプセルおよびその製造方法 |
| AR089441A1 (es) * | 2011-12-22 | 2014-08-20 | Baes Erik | Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica |
| KR102229492B1 (ko) * | 2013-01-05 | 2021-03-17 | 앤지 파마 유에스 엘엘씨 | 바이구아나이드를 포함하는 지연-방출 조성물 |
| WO2015200149A1 (en) * | 2014-06-23 | 2015-12-30 | Banner Life Sciences Llc | All natural enteric soft capsules comprising active ingredients |
| KR102305346B1 (ko) * | 2014-09-11 | 2021-09-28 | 겔리타 아게 | 젤라틴/펙틴 입자 |
| KR101917334B1 (ko) * | 2014-10-06 | 2018-11-09 | 후지 캡슐 가부시키가이샤 | 장용성 심리스 소프트 캡슐의 제조 방법 |
| CN108578381A (zh) * | 2018-02-27 | 2018-09-28 | 广州彤博士健康科技有限公司 | 可咀嚼性软胶囊外皮的配方及制备方法 |
| BR112021024375A2 (pt) * | 2019-06-03 | 2022-04-19 | Scherer Technologies Llc R P | Cápsulas de softgel de liberação retardada |
-
2020
- 2020-06-02 BR BR112021024375A patent/BR112021024375A2/pt unknown
- 2020-06-02 WO PCT/US2020/035666 patent/WO2020247352A1/en not_active Ceased
- 2020-06-02 CA CA3142702A patent/CA3142702A1/en active Pending
- 2020-06-02 MX MX2021014922A patent/MX2021014922A/es unknown
- 2020-06-02 JP JP2021571794A patent/JP7558204B2/ja active Active
- 2020-06-02 CN CN202080048407.5A patent/CN114072138A/zh active Pending
- 2020-06-02 US US17/596,059 patent/US20220354800A1/en active Pending
- 2020-06-02 AU AU2020288165A patent/AU2020288165A1/en active Pending
- 2020-06-02 KR KR1020217042800A patent/KR20220024189A/ko active Pending
- 2020-06-02 EP EP20819025.6A patent/EP3976022A4/en active Pending
- 2020-06-03 TW TW109118670A patent/TW202110426A/zh unknown
- 2020-06-03 AR ARP200101562A patent/AR119075A1/es unknown
-
2021
- 2021-12-02 IL IL288653A patent/IL288653A/en unknown
- 2021-12-29 CO CONC2021/0018071A patent/CO2021018071A2/es unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120301546A1 (en) | 2011-05-26 | 2012-11-29 | Hassan Emadeldin M | Acid-resistant soft gel compositions |
| CN104644609A (zh) | 2015-01-28 | 2015-05-27 | 龙标兵 | 一种功能性咀嚼型软胶囊皮 |
| JP2018531985A (ja) | 2015-10-30 | 2018-11-01 | アール．ピー． シェーラー テクノロジーズ エルエルシー | 延長放出性フィルムコーティングカプセル |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3976022A1 (en) | 2022-04-06 |
| AR119075A1 (es) | 2021-11-24 |
| KR20220024189A (ko) | 2022-03-03 |
| WO2020247352A1 (en) | 2020-12-10 |
| IL288653A (en) | 2022-02-01 |
| CA3142702A1 (en) | 2020-12-10 |
| JP2022535539A (ja) | 2022-08-09 |
| US20220354800A1 (en) | 2022-11-10 |
| MX2021014922A (es) | 2022-03-11 |
| EP3976022A4 (en) | 2023-06-14 |
| AU2020288165A1 (en) | 2022-01-06 |
| BR112021024375A2 (pt) | 2022-04-19 |
| TW202110426A (zh) | 2021-03-16 |
| CO2021018071A2 (es) | 2022-04-19 |
| CN114072138A (zh) | 2022-02-18 |
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