JP7533830B2 - 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物 - Google Patents

破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物 Download PDF

Info

Publication number
JP7533830B2
JP7533830B2 JP2023522277A JP2023522277A JP7533830B2 JP 7533830 B2 JP7533830 B2 JP 7533830B2 JP 2023522277 A JP2023522277 A JP 2023522277A JP 2023522277 A JP2023522277 A JP 2023522277A JP 7533830 B2 JP7533830 B2 JP 7533830B2
Authority
JP
Japan
Prior art keywords
composition
cells
processed product
osteoclasts
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2023522277A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022244447A1 (https=
Inventor
翼 中嶋
幸平 北村
寛子 中井
義隆 廣▲瀬▼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
House Wellness Foods Corp
Original Assignee
House Wellness Foods Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by House Wellness Foods Corp filed Critical House Wellness Foods Corp
Publication of JPWO2022244447A1 publication Critical patent/JPWO2022244447A1/ja
Priority to JP2024052694A priority Critical patent/JP7586361B2/ja
Application granted granted Critical
Publication of JP7533830B2 publication Critical patent/JP7533830B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/72Undefined extracts from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2023522277A 2021-05-17 2022-03-22 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物 Active JP7533830B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024052694A JP7586361B2 (ja) 2021-05-17 2024-03-28 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021083347 2021-05-17
JP2021083347 2021-05-17
PCT/JP2022/013051 WO2022244447A1 (ja) 2021-05-17 2022-03-22 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024052694A Division JP7586361B2 (ja) 2021-05-17 2024-03-28 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物

Publications (2)

Publication Number Publication Date
JPWO2022244447A1 JPWO2022244447A1 (https=) 2022-11-24
JP7533830B2 true JP7533830B2 (ja) 2024-08-14

Family

ID=84141538

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023522277A Active JP7533830B2 (ja) 2021-05-17 2022-03-22 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物
JP2024052694A Active JP7586361B2 (ja) 2021-05-17 2024-03-28 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024052694A Active JP7586361B2 (ja) 2021-05-17 2024-03-28 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物

Country Status (6)

Country Link
US (1) US20240252559A1 (https=)
EP (2) EP4700115A2 (https=)
JP (2) JP7533830B2 (https=)
CN (1) CN117279521A (https=)
TW (1) TW202313077A (https=)
WO (1) WO2022244447A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010095465A (ja) 2008-10-16 2010-04-30 House Wellness Foods Kk 乳酸菌含有免疫賦活用組成物
JP2015096476A (ja) 2013-11-15 2015-05-21 株式会社東洋新薬 コラーゲン産生促進用組成物、コラーゲン吸収促進用組成物、抗肥満用組成物
JP2017114814A (ja) 2015-12-24 2017-06-29 丸善製薬株式会社 化粧料
WO2019045037A1 (ja) 2017-09-01 2019-03-07 ハウスウェルネスフーズ株式会社 ヒアルロン酸産生促進用組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4064515B2 (ja) * 1998-02-13 2008-03-19 ハウスウェルネスフーズ株式会社 Il−12産生誘導組成物
JP5207313B2 (ja) 2008-05-30 2013-06-12 有限会社バイオメディカルリサーチグループ 乳酸菌配合物及びその製造方法
JP2010235534A (ja) 2009-03-31 2010-10-21 Fancl Corp 骨粗鬆症の予防又は治療用剤
KR101402926B1 (ko) * 2012-05-25 2014-06-03 한국 한의학 연구원 황련해독탕의 유산균 발효물을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학적 조성물 및 건강기능식품
KR101554875B1 (ko) * 2015-01-09 2015-09-24 (주) 와이디생명과학 락토바실러스 플란타룸 yd-212 균주 및 이를 이용하여 제조되는 발효물을 포함하는 조성물
KR20160086249A (ko) * 2015-07-27 2016-07-19 (주) 와이디생명과학 락토바실러스 플란타룸 yd-212 균주 및 이를 이용하여 제조되는 발효물을 포함하는 조성물

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010095465A (ja) 2008-10-16 2010-04-30 House Wellness Foods Kk 乳酸菌含有免疫賦活用組成物
JP2015096476A (ja) 2013-11-15 2015-05-21 株式会社東洋新薬 コラーゲン産生促進用組成物、コラーゲン吸収促進用組成物、抗肥満用組成物
JP2017114814A (ja) 2015-12-24 2017-06-29 丸善製薬株式会社 化粧料
WO2019045037A1 (ja) 2017-09-01 2019-03-07 ハウスウェルネスフーズ株式会社 ヒアルロン酸産生促進用組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
木元広実,Lactococcus lactis H61 の老化抑制効果と作用機構の解明に向けて,日本乳酸菌学会誌,2018年,29(2),pp.69-78

Also Published As

Publication number Publication date
EP4342535A1 (en) 2024-03-27
EP4342535A4 (en) 2025-04-23
JP2024075769A (ja) 2024-06-04
EP4700115A2 (en) 2026-02-25
JP7586361B2 (ja) 2024-11-19
CN117279521A (zh) 2023-12-22
JPWO2022244447A1 (https=) 2022-11-24
TW202313077A (zh) 2023-04-01
US20240252559A1 (en) 2024-08-01
WO2022244447A1 (ja) 2022-11-24

Similar Documents

Publication Publication Date Title
TWI594758B (zh) 包含雙歧桿菌的組合物、其製備方法及其用途
JP6551934B2 (ja) ビフィドバクテリウム属細菌および/または乳酸菌の増殖促進および/または減少抑制剤
JP2019513786A (ja) 除脂肪体重を増加させるためのビフィズス菌(Bifidobacterium)
CN114786692A (zh) 用于调节肠道免疫的新型益生菌组合物
JP2017197486A (ja) インターフェロンλ誘導剤
TW201701891A (zh) 大腸炎抑制劑
WO2015046407A1 (ja) 免疫疾患予防剤
TW200804591A (en) Lactic acid bacterium having immunoregulatory activity derived from moromi for wine fermentation
WO2020067422A1 (ja) T細胞を活性化するための組成物
JP5229977B2 (ja) 血中アディポネクチン濃度増加促進及び/又は減少抑制剤
JP5209294B2 (ja) インターロイキン12産生促進剤
JP7586361B2 (ja) 破骨前駆細胞の破骨細胞への分化抑制用組成物及び骨代謝改善用組成物
TWI705135B (zh) 抗齲齒劑及抗齲齒用組成物
WO2025022830A1 (ja) 免疫機能を相乗的に増強する組成物
TW202218552A (zh) 包含乳酸菌與脂肪酸的飼料及組成物
JP7331310B2 (ja) 免疫賦活活性を有する乳酸菌又はその処理物の保存時間経過による免疫賦活活性の低下を抑制するための組成物
JP7299744B2 (ja) 血中尿酸値低減用組成物、及び高尿酸血症予防又は改善用組成物、並びに、該組成物を用いた医薬品組成物及び飲食品組成物
TW201818828A (zh) 抑制腸道內乳桿菌屬乳酸菌減少用之組成物
JP7706190B2 (ja) ブラウティア属細菌
JP7706191B2 (ja) ブラウティア属細菌を用いた免疫賦活剤
JP7663240B2 (ja) 腸管免疫賦活剤及びIgA産生促進剤
JP7333732B2 (ja) 筋肉量及び/又は筋力の維持、或いは筋肉量及び/又は筋力の低下抑制用組成物、並びに、該組成物を用いた医薬品組成物及び飲食品組成物
JP7309436B2 (ja) 腎機能障害予防又は改善用組成物、並びに、該腎機能障害予防又は改善用組成物を用いた医薬品組成物及び飲食品組成物
JP7326075B2 (ja) 腎機能障害の予防又は改善用組成物、並びに、該組成物を用いた医薬品組成物及び飲食品組成物
TW202419100A (zh) 腸道障壁功能提升用及腸道上皮緊密連接增強用組成物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20230824

A625 Written request for application examination (by other person)

Free format text: JAPANESE INTERMEDIATE CODE: A625

Effective date: 20230920

A625 Written request for application examination (by other person)

Free format text: JAPANESE INTERMEDIATE CODE: A625

Effective date: 20231120

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20231121

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240130

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240328

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240702

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240716

R150 Certificate of patent or registration of utility model

Ref document number: 7533830

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150