JP7489326B2 - 組織の特性評価とスクリーニングのために改善したサイトメトリー - Google Patents

組織の特性評価とスクリーニングのために改善したサイトメトリー Download PDF

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JP7489326B2
JP7489326B2 JP2020563650A JP2020563650A JP7489326B2 JP 7489326 B2 JP7489326 B2 JP 7489326B2 JP 2020563650 A JP2020563650 A JP 2020563650A JP 2020563650 A JP2020563650 A JP 2020563650A JP 7489326 B2 JP7489326 B2 JP 7489326B2
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JP2021524911A5 (OSRAM
JP2021524911A (ja
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ナラカン アルヴィンダン，
スティーブン メヒ，
グアンチン オウ，
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ファイヴ プライム セラピューティクス インク
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G02—OPTICS
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    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B15/00—Optical objectives with means for varying the magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0088—Inverse microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00418—Means for dispensing and evacuation of reagents using pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B13/00—Optical objectives specially designed for the purposes specified below
    • G02B13/22—Telecentric objectives or lens systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes

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  • Health & Medical Sciences (AREA)
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  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
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  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2020563650A 2018-05-25 2019-05-23 組織の特性評価とスクリーニングのために改善したサイトメトリー Active JP7489326B2 (ja)

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JP2023214695A JP7827683B2 (ja) 2018-05-25 2023-12-20 組織の特性評価とスクリーニングのために改善したサイトメトリー

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US201862676620P 2018-05-25 2018-05-25
US62/676,620 2018-05-25
PCT/US2019/033755 WO2019226897A2 (en) 2018-05-25 2019-05-23 Enhanced cytometry for tissue characterization and screening

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JP2021524911A5 JP2021524911A5 (OSRAM) 2022-05-31
JP7489326B2 true JP7489326B2 (ja) 2024-05-23

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JP2023214695A Active JP7827683B2 (ja) 2018-05-25 2023-12-20 組織の特性評価とスクリーニングのために改善したサイトメトリー

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US (2) US12235264B2 (OSRAM)
EP (1) EP3803397A2 (OSRAM)
JP (2) JP7489326B2 (OSRAM)
CN (1) CN112470004A (OSRAM)
WO (1) WO2019226897A2 (OSRAM)

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US11346763B2 (en) 2019-12-18 2022-05-31 Jiangnan University Apparatus and method for microbial cell counting
CN110846217B (zh) * 2019-12-18 2024-07-05 江南大学 用于微生物细胞计数的仪器及方法
EP4337933A4 (en) 2021-05-14 2024-10-23 Becton, Dickinson and Company LIGHT DETECTION SYSTEMS BY SPECTRAL DISCRIMINATION AND METHODS OF USE THEREOF
WO2026008821A1 (en) * 2024-07-05 2026-01-08 Miltenyi Biotec B.V. & Co. KG Method for continuous single molecule localization of conventional fluorescent antibody probes

Citations (11)

* Cited by examiner, † Cited by third party
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JP2002544476A (ja) 1999-05-12 2002-12-24 アクララ バイオサイエンシーズ， インコーポレイテッド 微量流体デバイスにおける多重方式蛍光検出
JP2004093558A (ja) 2002-07-12 2004-03-25 Mitsubishi Chemicals Corp 分析用チップ、分析用チップユニット及び分析装置ならびに分析用チップの作製方法
WO2005031322A1 (ja) 2003-09-26 2005-04-07 Nikon Corporation 環境保持装置および環境制御型分析装置
JP2007278984A (ja) 2006-04-11 2007-10-25 Hamamatsu Photonics Kk 光測定装置、光測定方法、及び光測定プログラム
JP2008224465A (ja) 2007-03-14 2008-09-25 National Institute Of Advanced Industrial & Technology 微粒子測定方法及び装置
JP2009015047A (ja) 2007-07-05 2009-01-22 Nikon Corp 顕微鏡装置、及び観察方法
JP2010032513A (ja) 2008-07-25 2010-02-12 F Hoffmann-La Roche Ag 蛍光検出のための励起および結像光学素子
JP2013150567A (ja) 2012-01-25 2013-08-08 Hitachi High-Technologies Corp 核酸分析用反応デバイス、及び核酸分析装置
JP2014081321A (ja) 2012-10-18 2014-05-08 Fujikura Ltd 流路デバイス及び分析方法
JP2017049069A (ja) 2015-08-31 2017-03-09 国立研究開発法人理化学研究所 撮像装置、及び、生体情報取得装置
JP2018504628A (ja) 2015-01-26 2018-02-15 カリフォルニア インスティチュート オブ テクノロジー マルチウェル・フーリエ・タイコグラフィー撮像及び蛍光撮像

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101419170A (zh) * 1996-08-16 2009-04-29 Ge保健尼亚加拉公司 用于分析井板、凝胶和斑点的数字成像系统
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
EP3943915A3 (en) * 2014-05-12 2022-05-25 Cellomics, Inc Automated imaging of chromophore labeled samples

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002544476A (ja) 1999-05-12 2002-12-24 アクララ バイオサイエンシーズ， インコーポレイテッド 微量流体デバイスにおける多重方式蛍光検出
JP2004093558A (ja) 2002-07-12 2004-03-25 Mitsubishi Chemicals Corp 分析用チップ、分析用チップユニット及び分析装置ならびに分析用チップの作製方法
WO2005031322A1 (ja) 2003-09-26 2005-04-07 Nikon Corporation 環境保持装置および環境制御型分析装置
JP2007278984A (ja) 2006-04-11 2007-10-25 Hamamatsu Photonics Kk 光測定装置、光測定方法、及び光測定プログラム
JP2008224465A (ja) 2007-03-14 2008-09-25 National Institute Of Advanced Industrial & Technology 微粒子測定方法及び装置
JP2009015047A (ja) 2007-07-05 2009-01-22 Nikon Corp 顕微鏡装置、及び観察方法
JP2010032513A (ja) 2008-07-25 2010-02-12 F Hoffmann-La Roche Ag 蛍光検出のための励起および結像光学素子
JP2013150567A (ja) 2012-01-25 2013-08-08 Hitachi High-Technologies Corp 核酸分析用反応デバイス、及び核酸分析装置
JP2014081321A (ja) 2012-10-18 2014-05-08 Fujikura Ltd 流路デバイス及び分析方法
JP2018504628A (ja) 2015-01-26 2018-02-15 カリフォルニア インスティチュート オブ テクノロジー マルチウェル・フーリエ・タイコグラフィー撮像及び蛍光撮像
JP2017049069A (ja) 2015-08-31 2017-03-09 国立研究開発法人理化学研究所 撮像装置、及び、生体情報取得装置

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JP2024023740A (ja) 2024-02-21
US20250164475A1 (en) 2025-05-22
US12235264B2 (en) 2025-02-25
WO2019226897A3 (en) 2019-12-26
EP3803397A2 (en) 2021-04-14
US20210215687A1 (en) 2021-07-15
CN112470004A (zh) 2021-03-09
JP7827683B2 (ja) 2026-03-10
JP2021524911A (ja) 2021-09-16
WO2019226897A2 (en) 2019-11-28

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