JP7466876B2 - 自己組織化ペプチド - Google Patents

自己組織化ペプチド Download PDF

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Publication number
JP7466876B2
JP7466876B2 JP2021502130A JP2021502130A JP7466876B2 JP 7466876 B2 JP7466876 B2 JP 7466876B2 JP 2021502130 A JP2021502130 A JP 2021502130A JP 2021502130 A JP2021502130 A JP 2021502130A JP 7466876 B2 JP7466876 B2 JP 7466876B2
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Prior art keywords
sol
peptide
rada
gel transition
gel
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JP2021502130A
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Japanese (ja)
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JPWO2020171161A5 (https=
JPWO2020171161A1 (https=
Inventor
貴博 村岡
敦也 石田
逸樹 味岡
豪 渡辺
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Kitasato Institute
Tokyo University of Agriculture and Technology NUC
Tokyo Medical and Dental University NUC
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Kitasato Institute
Tokyo University of Agriculture and Technology NUC
Tokyo Medical and Dental University NUC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021502130A 2019-02-20 2020-02-20 自己組織化ペプチド Active JP7466876B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019028845 2019-02-20
JP2019028845 2019-02-20
PCT/JP2020/006745 WO2020171161A1 (ja) 2019-02-20 2020-02-20 自己組織化ペプチド

Publications (3)

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JPWO2020171161A1 JPWO2020171161A1 (https=) 2020-08-27
JPWO2020171161A5 JPWO2020171161A5 (https=) 2023-02-17
JP7466876B2 true JP7466876B2 (ja) 2024-04-15

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Family Applications (1)

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JP2021502130A Active JP7466876B2 (ja) 2019-02-20 2020-02-20 自己組織化ペプチド

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JP (1) JP7466876B2 (https=)
WO (1) WO2020171161A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230203116A1 (en) * 2020-07-30 2023-06-29 National University Corporation Tokyo Medical And Dental University Self-assembling peptide
CN113621028A (zh) * 2021-07-27 2021-11-09 南通大学 一种多肽自组装水凝胶支架及其应用
WO2023171577A1 (ja) * 2022-03-07 2023-09-14 公立大学法人名古屋市立大学 ニューロンの移動促進剤およびその利用
WO2023210774A1 (ja) * 2022-04-27 2023-11-02 国立研究開発法人科学技術振興機構 化合物及びその使用
CN117126244A (zh) * 2022-05-19 2023-11-28 南京海润医药有限公司 一种固相片段缩合制备自组装肽rada16的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515796A (ja) 2001-02-06 2005-06-02 マサチューセッツ　インスティテュート　オブ　テクノロジー ペプチド足場での組織細胞のカプセル化およびその使用
JP2008505919A (ja) 2004-07-06 2008-02-28 スリーディー マトリックス， インコーポレイテッド 精製両親媒性ペプチド組成物およびその使用
JP2008526749A (ja) 2005-01-04 2008-07-24 ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド 自己アセンブリするペプチドナノファイバーを用いたｐｄｇｆの徐放性の送達
JP2010504972A (ja) 2006-09-26 2010-02-18 マサチューセッツ・インスティテュート・オブ・テクノロジー 修飾自己組織化ペプチド

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515796A (ja) 2001-02-06 2005-06-02 マサチューセッツ　インスティテュート　オブ　テクノロジー ペプチド足場での組織細胞のカプセル化およびその使用
JP2008505919A (ja) 2004-07-06 2008-02-28 スリーディー マトリックス， インコーポレイテッド 精製両親媒性ペプチド組成物およびその使用
JP2008526749A (ja) 2005-01-04 2008-07-24 ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド 自己アセンブリするペプチドナノファイバーを用いたｐｄｇｆの徐放性の送達
JP2010504972A (ja) 2006-09-26 2010-02-18 マサチューセッツ・インスティテュート・オブ・テクノロジー 修飾自己組織化ペプチド

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WO2020171161A1 (ja) 2020-08-27
JPWO2020171161A1 (https=) 2020-08-27

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