JP7422666B2 - 睡眠時無呼吸を治療するための方法および組成物 - Google Patents
睡眠時無呼吸を治療するための方法および組成物 Download PDFInfo
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- JP7422666B2 JP7422666B2 JP2020542075A JP2020542075A JP7422666B2 JP 7422666 B2 JP7422666 B2 JP 7422666B2 JP 2020542075 A JP2020542075 A JP 2020542075A JP 2020542075 A JP2020542075 A JP 2020542075A JP 7422666 B2 JP7422666 B2 JP 7422666B2
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- oxybutynin
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- atomoxetine
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| EP4635514A3 (en) | 2019-02-08 | 2025-12-24 | The Brigham & Women's Hospital, Inc. | Methods and compositions for treating sleep apnea |
| WO2021091902A1 (en) * | 2019-11-04 | 2021-05-14 | Apnimed, Inc. (Delaware) | Combination pharmacological interventions for multiple mechanisms of obstructive sleep apnea |
| CN116391233A (zh) * | 2020-09-30 | 2023-07-04 | 皇家飞利浦有限公司 | 用于执行剂量滴定的方法和系统 |
| WO2022187420A1 (en) * | 2021-03-04 | 2022-09-09 | Apnimed, Inc. (Delaware) | Combination of reboxetine and a muscarinic receptor antagonist (mra) for use in treating sleep apnea |
| GEAP202416361A (en) * | 2021-03-24 | 2024-04-25 | Apnimed Inc Delaware | Methods and compositions for treating sleep apnea |
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| KR20240021920A (ko) * | 2021-06-17 | 2024-02-19 | 애프니메드, 인코포레이티드 (델라웨어) | 수면 무호흡증을 치료하기 위한 노르에피네프린 재흡수 억제제 |
| US20250049779A1 (en) | 2021-12-22 | 2025-02-13 | Bayer Aktiengesellschaft | Combination of an a2-adrenoceptor subtype c (alpha-2c) antagonist with a norepinephrine reuptake inhibitor for the treatment of sleep apnea |
| MX2024007767A (es) | 2021-12-22 | 2024-07-04 | Bayer Ag | Combinacion de un antagonista del adrenoceptor a2 subtipo c (alfa-2c) con un antagonista del receptor muscarinico para el tratamiento de la apnea del sue?o. |
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| JP2012176958A (ja) | 2012-04-20 | 2012-09-13 | Watson Pharmaceuticals Inc | （ｒ）−オキシブチニンおよび（ｒ）−デスエチルオキシブチニンによる平滑筋機能亢進の処置 |
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Patent Citations (3)
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| JP2003523382A (ja) | 2000-02-24 | 2003-08-05 | ファルマシア・アンド・アップジョン・カンパニー | 新規な薬物の組合せ |
| JP2012176958A (ja) | 2012-04-20 | 2012-09-13 | Watson Pharmaceuticals Inc | （ｒ）−オキシブチニンおよび（ｒ）−デスエチルオキシブチニンによる平滑筋機能亢進の処置 |
| JP2020517719A (ja) | 2017-04-28 | 2020-06-18 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | 睡眠時無呼吸を治療する方法及び組成物 |
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| Atomoxetine and Oxybutynin in Obstructive Sleep Apnea (ATOSA) / Study NCT02908529 on Date: January 17, 2018 (v3)，ClinicalTrials.gov archive [online]，U. S. National Library of Medicine，2018年01月17日，https://clinicaltrials.gov/ct2/history/NCT02908529?A=3&B=3&C=merged#StudyPageTop |
| The Journal of Pharmacology and Experimental Therapeutics，1991年，Vol.256, No.2，p.562-567 |
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