MX2020008086A - Metodos y composiciones para tratar la apnea del sue?o. - Google Patents

Metodos y composiciones para tratar la apnea del sue?o.

Info

Publication number
MX2020008086A
MX2020008086A MX2020008086A MX2020008086A MX2020008086A MX 2020008086 A MX2020008086 A MX 2020008086A MX 2020008086 A MX2020008086 A MX 2020008086A MX 2020008086 A MX2020008086 A MX 2020008086A MX 2020008086 A MX2020008086 A MX 2020008086A
Authority
MX
Mexico
Prior art keywords
methods
sleep apnea
compositions
treating sleep
nri
Prior art date
Application number
MX2020008086A
Other languages
English (en)
Inventor
Lawrence G Miller
Barry Wohl
Walter J Lunsmann
Original Assignee
Apnimed Inc Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apnimed Inc Delaware filed Critical Apnimed Inc Delaware
Publication of MX2020008086A publication Critical patent/MX2020008086A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

En general, la invención se refiere a composiciones farmacéuticas que comprenden (R)-oxibutinina y un inhibidor de la recaptación de la norepinefrina (IRN), y a métodos para tratar la apnea del sueño que comprenden administrar (R)-oxibutinina y un inhibidor de la recaptación de la norepinefrina (IRN). En algunas realizaciones, el IRN es atomoxetina.
MX2020008086A 2018-01-30 2019-01-30 Metodos y composiciones para tratar la apnea del sue?o. MX2020008086A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862623892P 2018-01-30 2018-01-30
PCT/US2019/015781 WO2019152475A1 (en) 2018-01-30 2019-01-30 Methods and compositions for treating sleep apnea

Publications (1)

Publication Number Publication Date
MX2020008086A true MX2020008086A (es) 2021-02-15

Family

ID=65441079

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020008086A MX2020008086A (es) 2018-01-30 2019-01-30 Metodos y composiciones para tratar la apnea del sue?o.

Country Status (14)

Country Link
US (2) US11911351B2 (es)
EP (1) EP3746126A1 (es)
JP (2) JP7422666B2 (es)
KR (1) KR20200115598A (es)
CN (1) CN111670050A (es)
AU (1) AU2019214891A1 (es)
BR (1) BR112020015316A2 (es)
CA (1) CA3089712A1 (es)
EA (1) EA202091597A1 (es)
IL (1) IL276247A (es)
MA (1) MA52861A (es)
MX (1) MX2020008086A (es)
SG (1) SG11202007226UA (es)
WO (1) WO2019152475A1 (es)

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KR20240042261A (ko) * 2017-04-28 2024-04-01 더 브리검 앤드 우먼즈 하스피털, 인크. 수면 무호흡을 치료하기 위한 방법 및 조성물
US20220362221A1 (en) * 2019-11-04 2022-11-17 Apnimed, Inc. (Delaware) Combination pharmacological interventions for multiple mechanisms of obstructive sleep apnea
JP2024508498A (ja) * 2021-03-04 2024-02-27 アプニメッド，インコーポレイテッド（デラウェア） 睡眠時無呼吸の治療における使用のためのレボキセチン及びムスカリン受容体拮抗薬（ｍｒａ）の組み合わせ
WO2022204228A1 (en) * 2021-03-24 2022-09-29 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea
KR20240004600A (ko) 2021-05-04 2024-01-11 애프니메드, 인코포레이티드 (델라웨어) (r)-옥시부티닌 d-말레이트의 고체 형태
BR112023026158A2 (pt) * 2021-06-17 2024-03-05 Apnimed Inc Delaware Inibidores da recaptação de norepinefrina para tratamento da apneia do sono
TW202342033A (zh) 2021-12-22 2023-11-01 德商拜耳廠股份有限公司 用於治療睡眠呼吸中止之α２－腎上腺素受體亞型Ｃ（α－２Ｃ）拮抗劑與正腎上腺素再吸收抑制劑之組合
TW202342011A (zh) 2021-12-22 2023-11-01 德商拜耳廠股份有限公司 用於治療睡眠呼吸中止之α２－腎上腺素受體亞型Ｃ（α－２Ｃ）拮抗劑與蕈毒鹼受體拮抗劑之組合
WO2023219991A1 (en) * 2022-05-13 2023-11-16 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea

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Also Published As

Publication number Publication date
US11911351B2 (en) 2024-02-27
US20210038541A1 (en) 2021-02-11
US20220378724A1 (en) 2022-12-01
JP2021516218A (ja) 2021-07-01
IL276247A (en) 2020-09-30
CA3089712A1 (en) 2019-08-08
MA52861A (fr) 2021-05-05
KR20200115598A (ko) 2020-10-07
SG11202007226UA (en) 2020-08-28
WO2019152475A1 (en) 2019-08-08
JP2023181322A (ja) 2023-12-21
EA202091597A1 (ru) 2020-10-22
JP7422666B2 (ja) 2024-01-26
CN111670050A (zh) 2020-09-15
EP3746126A1 (en) 2020-12-09
BR112020015316A2 (pt) 2020-12-08
AU2019214891A1 (en) 2020-08-20

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